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Clokeran 2 Tablet

Prescription Required
SALT COMPOSITION
Storage
Store in a refrigerator (2 - 8°C). Do not freeze.

Product introduction

Clokeran 2 Tablet is used in the treatment of some cancers of blood and lymphatic system. It may be also used to treat other kinds of cancer, as determined by the doctor. It is used alone or in combination with other cancer medicines.

Clokeran 2 Tablet should be taken empty stomach, or 1 hour before and 2 hours after a meal. But, try to have it at the same time every day for most benefits. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include anemia (low number of red blood cells), decreased blood cells (red cells, white cells, and platelets) decreased white blood cell count, infection,  nausea and vomiting. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them.

Inform your doctor if you have a medical history, of bleeding disorders, heart or liver disease, radiation treatment or any infection. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is known to reduce the number of blood cells in your blood thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with kidney, liver and heart function during treatment with this medicine. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Clokeran Tablet

Benefits of Clokeran Tablet

In Blood cancer

Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body's ability to fight infection. Clokeran 2 Tablet kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

In Hodgkin’s disease

Hodgkin’s disease is a type of lymphoma, which is a blood cancer that starts in the lymphatic system. The lymphatic system helps the immune system get rid of waste and fight infections. Clokeran 2 Tablet kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. Take it as prescribed and follow your doctor’s instructions carefully.

Side effects of Clokeran Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Clokeran

  • Anemia (low number of red blood cells)
  • Decreased blood cells (red cells, white cells, and platelets)
  • Decreased white blood cell count (neutrophils)
  • Decreased white blood cell count
  • Bone marrow suppression
  • Nausea
  • Vomiting
  • Diarrhea
  • Mouth ulcer

How to use Clokeran Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Clokeran 2 Tablet is to be taken empty stomach.

How Clokeran Tablet works

Clokeran 2 Tablet is an anti-cancer medication. It works by damaging the genetic material (DNA and RNA) of the cancer cells. This stops their growth and multiplication.

Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Clokeran 2 Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Clokeran 2 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
UNSAFE
Clokeran 2 Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
CONSULT YOUR DOCTOR
It is not known whether Clokeran 2 Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
CAUTION
Clokeran 2 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Clokeran 2 Tablet may be needed. Please consult your doctor.
Careful monitoring by a doctor is important as kidney disease patients are at an increased risk of bone marrow depression and inflammation and infections of urinary bladder while taking this medicine.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Clokeran 2 Tablet in patients with liver disease. Please consult your doctor.

What if you forget to take Clokeran Tablet?

If you miss a dose of Clokeran 2 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Clokeran 2 Tablet
₹31.03/Tablet
Halkeran 2 Tablet
Halsted Pharma Private Limited
₹40.4/tablet
30% costlier

Quick tips

  • Clokeran 2 Tablet should be taken one hour before a meal or two hours after a meal. 

Fact Box

Chemical Class
Nitrogen Mustard Compounds
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Alkylating agent

Patient concerns

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Can blood cancer patients 1st stage do sex with normal girl Sir a blood cancer patients do sex with normal girl can any problem or cause doing with girl or side effect give suggestions Thanks
Dr. Vijay Sharnangat
Medical Oncology and Hematology
Wait till blood cancer gets cured.
Is chest cancer a fetal disease
Dr. Vijay Sharnangat
Medical Oncology and Hematology
If it is not localised
arrow

User feedback


FAQs

Q. How is Clokeran 2 Tablet administered?

Clokeran 2 Tablet is administered orally in tablet form.

Q. Why is Clokeran 2 Tablet toxic to cancer cells/ how does Clokeran 2 Tablet work?

Clokeran 2 Tablet belongs to a class of drugs called nitrogen mustard derivatives which kill the cancer cells by interfering with DNA replication, and also by directly slowing or stopping their growth.

Q. Does Clokeran 2 Tablet cause hair loss/constipation?

No, hair loss or constipation has not been reported with the use of Clokeran 2 Tablet.

Q. What is Clokeran 2 Tablet used for?

Clokeran 2 Tablet is used to treat some types of blood cancers like Hodgkin's disease (cancer that starts in blood cells that are part of immune system), certain forms of non-Hodgkin's lymphoma, chronic lymphocytic leukemia (disease where the bone marrow produces a large number of abnormal white cells. It is also used to treat Waldenstrom's macroglobulinaemia (rare blood condition involving the release of an abnormal protein, macroglobulin, into the blood).

Q. How is Clokeran 2 Tablet excreted?

Clokeran 2 Tablet is metabolized in liver to form nontoxic compounds which are excreted in urine.

Q. Does Clokeran 2 Tablet need to be refrigerated?

Clokeran 2 Tablet has to be stored in a refrigerator at a temperature between 2 °C – 8 °C.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1684.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 243-44.
  3. Chlorambucil. Dublin, Ireland: Aspen; 2006 [revised Mar. 2015]. [Accessed 26 Mar. 2019] (online) Available from:External Link
  4. Chlorambucil. Research Triangle Park, NC: GlaxoSmithKline; [Accessed 26 Mar. 2019] (online) Available from:External Link
  5. Medscape. Chlorambucil. [Accessed 26 Mar. 2019] (online) Available from:External Link

Marketer details

Name: Natco Pharma Ltd
Address: Natco House, Road No.2, Banjara Hills, Hyderabad-500 034, India
Country of origin: India
Expires on or after: January, 2025

A licensed vendor partner from your nearest location will deliver Clokeran 2 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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30.0 tablets in 1 strip
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