Cislieva Injection

Reviewed By Dr. Rajeev Sharma, MBA, MBBS

Last updated on 14 Dec 2025 | 01:00 AM (IST)

Cislieva Injection is a prescription medicine used in the treatment of ovarian, cervical, and testicular cancers. It works by stopping or slowing down the growth of cancer cells in the body.

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Cislieva Injection

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Stritin 50mg Injection

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Cisplatin (50mg)

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General Information

Contains

Cisplatin (50mg)

Marketer

Allieva Pharma

Storage

Store below 30°C

The content is shown in English

Product introduction

Cislieva Injection is given as an injection into veins by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Injection site reaction (pain, swelling, redness), nausea, and vomiting are some common side effects of this medicine. Hearing problems or ear damage is a serious side effect of this medicine, hence your doctor might get a hearing test both before and during treatment with this medicine. It may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver, and kidney function.

Before taking this medicine, let your doctor if you have or had kidney disease as the medicine affects the functioning of the kidney. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. It may cause infertility in men, hence they should seek medical advice about sperm freezing before beginning treatment.

Uses of Cislieva Injection

Benefits of Cislieva Injection

Ovarian cancer
Cislieva Injection is used to treat ovarian cancer by helping destroy cancer cells and slow disease progression. It supports tumor shrinkage and enhances the effectiveness of surgery or other therapies.

Cervical cancer
In cervical cancer, Cislieva Injection helps control the spread of abnormal cells and improves outcomes when used alongside radiation or in advanced-stage treatment plans.

Testicular cancer
Cislieva Injection is highly effective in treating testicular cancer by targeting and killing cancer cells. It plays a key role in achieving high cure rates, especially when combined with other chemotherapy drugs.

How to use Cislieva Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Cislieva Injection works

Cislieva Injection is an anti-cancer medication. It works by damaging the genetic material (DNA and RNA) of the cancer cells which stops their growth and multiplication.

All substitutes for Cislieva Injection

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Cislieva Injection is given as an injection under the supervision of a doctor.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Cislieva Injection. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Cislieva Injection is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

UNSAFE

Cislieva Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

UNSAFE

Cislieva Injection may cause side effects that could affect your ability to drive.
Cislieva Injection may cause side effects such as feeling sleepy and/or vomiting which could affect your ability to drive.

Kidney

CAUTION

Cislieva Injection should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Use of Cislieva Injection is not recommended in patients with severe kidney disease.

Liver

SAFE IF PRESCRIBED

Cislieva Injection is probably safe to use in patients with liver disease. Limited data suggest dose adjustment may not be needed.

Interaction with drugs

Taking Cislieva with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Vancomycin (Injection Route)

If concurrent use is essential, your doctor may closely monitor your kidney's functioning and overall treatment.

Severe

Pemetrexed (Injection Route)

If concurrent use is essential, watch out for symptoms such as nausea, vomiting, diarrhea, mouth sores, fatigue, hair loss, rash, numbness or tingling in the hands & feet and consult your doctor if you experience them. They may adjust the doses as per the observations. Pemetrexed may increase the metabolism of Cisplatin.

Severe

Cholera Vaccine (Inactivated) (Oral Route)

Do not use Cisplatin with Cholera Vaccine (Inactivated). If Cisplatin is essential, ensure a gap of At least 6 months after discontinuing Cholera Vaccine (Inactivated). Please consult your doctor. Cisplatin may reduce efficacy of Cholera Vaccine (Inactivated).

Severe

Furosemide (Oral Route)

Your doctor may regularly monitor and check your hearing ability.

Severe

Furosemide (Injection Route)

Your doctor may regularly monitor and check your hearing ability.

Frequently asked questions

Is Cislieva Injection an anticancer medicine?

Yes, Cislieva Injection is an anticancer medicine that is used for the treatment of ovarian, cervical, and testicular cancer.

How will you know that Cislieva Injection is working?

Keep taking this medicine exactly as directed until your doctor tells you to stop. Regular scans will reveal whether your tumor is responding to the treatment. Your doctor will determine when those scans should be scheduled.

Are there any serious side effects of Cislieva Injection?

You need to seek medical help immediately if you notice severe allergic reactions like rashes, difficulty breathing, swelling of face, lips, tongue, change in heartbeats, uncontrollable nausea and vomiting, reduced urination, swelling of feet or lower legs, pain in the lower back or side, muscle cramps, paralysis or numbness of the face, arm or leg and unusual bleeding such as bleeding gum, blood in urine or stools.

Does Cislieva Injection cause hair loss?

Yes, while taking this medicine, your hair may become brittle and break. You may also experience patchy hair loss or thinning. These conditions tend to resolve once treatment is stopped. Be gentle when brushing and washing hair to manage hair loss.

Are there any precautions for tingling sensation and numbness in my arms and legs?

This medicine causes tingling, numbness, pain, or burning sensation in your arms or legs. Be careful when moving around, as the numbness may make it harder to walk, feel your hands or feet, or increase your risk of falls. Talk to your doctor if you feel these symptoms. You may need to change your dose or schedule.

I have noticed some changes in my skin after taking Cislieva Injection? What should I do?

Use a moisturizer to get relief from rashes, dry and itchy skin. Avoid direct sunlight, wear protective clothing, and use sunscreen with (SPF more than 15) whenever you step outdoors. Do not go swimming if you have a rash because the chlorine in the water can make it worse. Avoid hot water bath and wear loose and cotton fabric clothes. Your skin will tend to become better once treatment is stopped.

I am experiencing nausea and vomiting. Is this due to Cislieva Injection?

Nausea and vomiting are some of the common side-effects of this medicine. Your doctor might prescribe you medications to prevent you from feeling sick. Your symptoms will be better managed if you take your medication regularly to prevent sickness rather than use it only when sickness occurs. Along with that, eat smaller, more frequent meals to reduce the feeling of nausea. Avoid food that is salty, spicy, fried, or fatty, and drink plenty of water.

Can I drink alcohol while taking Cislieva Injection?

Avoid alcohol while on treatment with this medicine. This is because side effects like dizziness and drowsiness might become worse.

What precautions should I take to reduce the chances of getting infected during treatment with Cislieva Injection?

Since Cislieva Injection lowers the number of white blood cells and platelets in your blood, it puts you at risk of getting an infection or bleeding. In order to prevent, avoid people who have infections. Check with your doctor immediately if you think you may be getting an infection, or if you get a fever, chills, cough; be careful not to cut yourself when you are using sharp objects such as a razor or nail cutters, and use a toothbrush with soft bristles to prevent bleeding from gums.

Fact Box

Chemical Class

Transition metal chlorides

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Platinum-Based Alkylating Agents

Related lab tests

Beta Human Chorionic Gonodotropin,Tumor marker

Human Papilloma Virus

Papanicolaou (PAP) Cytology

References

Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1689.
Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 944.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 279-80.
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 26 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Allieva Pharma
Address: 14/16/1, GROUND FLOOR, SAHIBABAD INDUSTRIAL AREA, GHAZIABAD, U.P.-201010

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Provide right medicines

Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose

In accordance with the law

Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945

Cislieva Injection

Save more with additional offers

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Cislieva Injection

Benefits of Cislieva Injection

How to use Cislieva Injection

How Cislieva Injection works

All substitutes for Cislieva Injection

Celplat 50mg Injection

Stritin 50mg Injection

Sancis 50mg Injection

Cismax 50mg Injection

Cisbet 50mg Injection

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Vancomycin (Injection Route)

Pemetrexed (Injection Route)

Cholera Vaccine (Inactivated) (Oral Route)

Furosemide (Oral Route)

Furosemide (Injection Route)

Frequently asked questions

Is Cislieva Injection an anticancer medicine?

How will you know that Cislieva Injection is working?

Are there any serious side effects of Cislieva Injection?

Does Cislieva Injection cause hair loss?

Are there any precautions for tingling sensation and numbness in my arms and legs?

I have noticed some changes in my skin after taking Cislieva Injection? What should I do?

I am experiencing nausea and vomiting. Is this due to Cislieva Injection?

Can I drink alcohol while taking Cislieva Injection?

What precautions should I take to reduce the chances of getting infected during treatment with Cislieva Injection?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Beta Human Chorionic Gonodotropin,Tumor marker

Human Papilloma Virus

Papanicolaou (PAP) Cytology

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests