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Choltran 5mg Tablet

Written By Dr. Syeda Aafia, MBA, BDS
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS
Last updated on 02 Apr 2026 | 05:32 PM (IST)
Choltran 5mg Tablet is used to lower cholesterol and reduce the risk of heart disease. Cholesterol is a fatty substance that builds up in your blood vessels and causes narrowing of blood vessels, which may lead to cardiac problems.
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General Information

The content is shown in English
Choltran 5mg Tablet image
Choltran 5mg Tablet image

Product introduction

Choltran 5mg Tablet may also be used to treat skin itching seen in certain types of liver disease and to relieve some types of diarrhea. This medicine may be used alone or in combination with other medicines. It may be taken with a meal or on an empty stomach. You can take it at any time of day, but try to take it at the same time each day. Most people with high cholesterol do not feel ill, but if you stop taking this medicine, your condition could get worse unless the doctor suggests it.


The most common side effect of this medicine is constipation. However, some patients in rare cases may also experience nausea, vomiting, diarrhea, bloating, or indigestion. Before taking it, let your doctor know if you are suffering from any liver or kidney disease.


It is important to have your cholesterol levels checked regularly. Choltran 5mg Tablet is only one part of a treatment program, which should also include a healthy diet, regular exercise, smoking cessation, moderation of alcohol intake, and weight reduction. You can eat normally while taking this medicine, but try to avoid foods high in fat. Pregnant and breastfeeding women should consult their doctor before taking this medicine to make sure it is safe for them.

Uses of Choltran Tablet

Benefits of Choltran Tablet

High cholesterol
Choltran 5mg Tablet helps lower high cholesterol levels, especially for those who need extra support beyond diet and lifestyle changes. It works by reducing harmful cholesterol in the blood, which can lower the risk of heart disease and other cardiovascular problems. By keeping cholesterol levels in check, Choltran 5mg Tablet helps protect heart health and supports overall well-being.

Side effects of Choltran Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Choltran
  • Constipation

How to use Choltran Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Choltran 5mg Tablet may be taken with or without food.

How Choltran Tablet works

Choltran 5mg Tablet helps lower cholesterol by reducing the amount of cholesterol absorbed in the body. It works by trapping bile acids, which are made from cholesterol, in the intestine. Since the body needs bile acids for digestion, it uses more cholesterol to make new ones. This process helps lower bad cholesterol (LDL) levels in the blood and supports overall health.

Quick tips

  • Take Choltran 5mg Tablet with a full glass of water after taking food.
  • It may interfere with the absorption of vitamins such as A, D, and K. Take supplements of these vitamins as suggested by your doctor.
  • It can delay or decrease the absorption of certain medicines. Any other medicine should be taken 1 hour before or 4 hours after taking Choltran 5mg Tablet.

Safety advice

Alcohol

Alcohol

UNSAFE
It is unsafe to consume alcohol with Choltran 5mg Tablet
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Choltran 5mg Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

SAFE IF PRESCRIBED
Available human data suggest that the drug does not pass into breast milk in clinically significant amounts and is unlikely to harm the infant.
Driving

Driving

SAFE
Choltran 5mg Tablet does not usually affect your ability to drive.
Kidney

Kidney

SAFE IF PRESCRIBED
Choltran 5mg Tablet is safe to use in patients with kidney disease. No dose adjustment is recommended.
Liver

Liver

CONSULT YOUR DOCTOR
There is limited data available on the use of Choltran 5mg Tablet in patients with liver disease.

Interaction with drugs

Taking Choltran with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Raloxifene (Oral Route)

Do not consume Raloxifene with Cholestyramine.
Moderate

Paracetamol (Oral Route)

If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations. Paracetamol may increase the effect of Cholestyramine.
Moderate

Chloroquine (Oral Route)

To take Chloroquine, ensure a gap of 1 hour before or 6 hours after taking Cholestyramine.
Moderate

Dexamethasone (Oral Route)

To take Dexamethasone, ensure a gap of 1 hour before and 6 hours after taking Cholestyramine.
Moderate

Ursodeoxycholic Acid (Oral Route)

Ensure a gap of at least 2 hours between taking Ursodeoxycholic Acid and Cholestyramine. Your doctor may monitor the effects of Ursodeoxycholic Acid. Cholestyramine may reduce blood levels of Ursodeoxycholic Acid.

Frequently asked questions

You should not take Choltran 5mg Tablet if you have a blockage in your stomach or intestines. Consult your doctor in case of any doubts.
Choltran 5mg Tablet helps lower high cholesterol and thus the risk of heart diseases. If you stop taking this medicine, your blood cholesterol levels may increase again. Your doctor may advise you to follow a special diet and lifestyle to help prevent this from happening. Never stop taking this medicine without consulting your doctor.
Choltran 5mg Tablet works by binding to bile acid (fluid secreted by the liver ) in your intestines. Once it attaches to the bile acid, it forms a complex and is removed from your body. As a result of this, the bile acid levels are lowered which makes your liver convert more cholesterol into bile acid in order to replace what was lost. This lowers the amount of cholesterol in your body.
Constipation is a very common side effect of this medicine because of the way it works. Normally, bile acids in the intestine help control how much water is in your stool which in turn regulates your bowel movement. By binding to bile acid, this medication may remove some water in your stool, causing constipation. To get relief from constipation, increase your water intake and include fiber-rich food like green vegetables, fruits, cereals in your diet.
Cholesterol is a waxy fat, or lipid, which moves throughout your body in your blood. Your liver makes cholesterol, but you can also get it from foods. There are two types of cholesterol HDL (high-density lipoprotein) or the good cholesterol and LDL (low-density lipoprotein) or the bad cholesterol.
LDL or low-density lipoprotein is called bad cholesterol because it causes a buildup of cholesterol in the blood. This leads to blockage in the heart and is a direct cause of heart attacks, strokes, and peripheral artery disease.
HDL or high-density lipoprotein is also called as good cholesterol because it carries cholesterol from your blood to your liver to be removed. This reduces the risk of heart diseases.
You can book a lipid profile test with any accredited laboratory. This test helps you monitor your total cholesterol, LDL levels, HDL levels, triglycerides, and the ratio between cholesterol and HDL. You may need to fast for a period of 10-12 hours before giving your blood sample to the laboratory. After receiving your test report, consult a doctor to help you evaluate your test results.
Your total cholesterol level should be 125 to 200mg/dL, LDL should be less than 100mg/dL and HDL should be 40mg/dL or higher.
If you have a high cholesterol level, it builds upon the walls of your arteries. This condition causes arteries to become narrow, and the narrowed blood vessels reduce blood flow to the heart. This can lead to a heart attack or stroke.
Medication is typically prescribed when your cholesterol levels are high enough (LDL level greater than 190mg/dL) to increase your risk for heart disease or if you already have a history of a heart attack or stroke. Always consult your doctor before taking any medications.
Some of the most common symptoms of high cholesterol are chest pain, pain in the neck, jaw, upper abdomen, or back, extreme fatigue, difficulty breathing, numbness or coldness in your extremities.
Some of the foods with high cholesterol are red meat like lamb, pork, packaged food, fried foods, full-fat dairy, processed meat (sausage, bacon), etc.
Along with taking Choltran 5mg Tablet, taking a low-fat diet, regular exercise, reducing body weight, and limiting alcohol consumption can help improve the effectiveness of this medicine and lower cholesterol levels.

Fact Box

Chemical Class

Anion exchange resins

Habit Forming

No

Therapeutic Class

CARDIAC

Action Class

Bile Acid Sequestrants (BASs)

References

  1. Bersot TP. Drug Therapy for Hypercholesterolemia and Dyslipidemia. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 898-99.
  2. Malloy MJ, Kane JP. Agents Used in Dyslipidemia. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 615-16.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 258.
  4. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Cholestyramine. [Updated 2018 Oct 31]. [Accessed 19 Feb. 2020] (online) Available from:
  5. Central Drugs Standard Control Organisation (CDSCO). Cholestyramine. [Accessed 15 Mar. 2019] (online) Available from:
  6. Cholestyramine [Product Information]. Spring Valley, NY: Par Pharmaceutical Inc; 2005. [Accessed 25 Jul. 2024] (online) Available from:
  7. Cholestyramine [Product Information]. Kelambakkam, India: Par Formulations Private Limited.; 2023. [Accessed 08 Mar. 2025] (online) Available from:
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User feedback

Twice A Day
31%
Once A Day
31%
Thrice A Day
23%
Four Times A Day
15%
High cholesterol
50%
Others
50%
Poor
100%
Constipation
100%
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Ajanta Pharma Limited
Address: Ajanta House, Charkop, Kandivli West, Mumbai 400 067, India

Vendor Details

Country of origin: India
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