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MMST, MBBS
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MD (Pharmacology), MBBS
Last updated on:
15 Jul 2019 | 05:17 PM (IST)
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Celkeran 5 mg Tablet


Overview

Uses of Celkeran Tablet

Celkeran Tablet side effects

Common
  • Nausea
  • Vomiting
  • Mouth ulcer
  • Anemia (low number of red blood cells)
  • Decreased blood cells (red cells, white cells, and platelets)
  • Bone-marrow suppression
  • Decreased white blood cell count
  • Diarrhea
  • Decreased white blood cell count (neutrophils)

How to use Celkeran Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Celkeran 5 mg Tablet is to be taken empty stomach.

How Celkeran Tablet works

Celkeran 5 mg Tablet is an anti-cancer medication. It works by damaging the genetic material (DNA and RNA) of the cancer cells. This stops their growth and multiplication.

Celkeran Tablet related warnings

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Celkeran 5 mg Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Celkeran 5 mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Lactation
UNSAFE
Celkeran 5 mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
CONSULT YOUR DOCTOR
It is not known whether Celkeran 5 mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
CAUTION
Celkeran 5 mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Celkeran 5 mg Tablet may be needed. Please consult your doctor.
Careful monitoring by a doctor is important as kidney disease patients are at an increased risk of bone marrow depression and inflammation and infections of urinary bladder while taking this medicine.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Celkeran 5 mg Tablet in patients with liver disease. Please consult your doctor.

What if you miss a dose of Celkeran Tablet?

If you miss a dose of Celkeran 5 mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Celkeran 5 mg Tablet
₹77.48/Tablet
Clokeran 5mg Tablet
Natco Pharma Ltd
₹73/Tablet
save 6%
Chloramax 5 Tablet
GLS Pharma Ltd.
₹79/Tablet
2% costlier
Radix AQ 5mg Tablet
GLS Pharma Ltd.
₹79/Tablet
2% costlier

Expert Advice

  • Do not receive live vaccine (such as measles, mumps, rubella and others) while using chlorambucil, and avoid contact with anyone who has recently received a live vaccine as there are chances that the virus could be passed on to you.
  • You may be regularly monitored for blood count while taking chlorambucil.
  • Do not take chlorambucil if you have recently undergone radiotherapy or received other cytotoxic agents.
  • Caution has to be followed if you have a liver or kidney problems. 
  • Regular monitoring is required if your child is having nephrotic syndrome; or if you have been prescribed high pulse dosing regimens and have a history of seizure disorder.
  • Do not take chlorambucil if you have rare hereditary problems of glucose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption should not take this medication.
  • Tell your doctor if you are or planning to become pregnant or are breastfeeding.

Patient Concerns

Questions Related to Celkeran

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suggest any medicine to recover from low haemoglobin .I have blood cancer and heart problems too. My haemoglobin remains between 8 - 10 .Suggest me some remedy to rise and maintain the minimum haemoglobin of 12 ?
Dr. Aanchal Maheshwari
Ayurveda
Regularly take kwath of bhuiamla 20 ml twice, tablet abhrlauh 20 ml twice after meal
I tested for lymphomb test , it show that my white blood cell are multiply than i feel itchy skin and lumps on my skin , if i take deflazacort and levocetrizine than i feel batter but steroid can not take more , so is there any prrmantely solution of this promblemDoctors said that it is one blood cancer type disease
Dr. Vijay Sharnangat
Cancer Specialist
Get evaluated for that
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Do you have any questions related to Celkeran 5 mg Tablet?

User Feedback


FAQs

Q. How is Celkeran administered?

Celkeran is administered orally in tablet form

Q. Why is Celkeran toxic to cancer cells/ how does Celkeran work?

Celkeran belongs to a class of drugs called nitrogen mustard derivatives which kill the cancer cells by interfering with DNA replication, and also by directly slowing or stopping their growth

Q. Does Celkeran cause hair loss/constipation?

No, hair loss or constipation has not been reported with the use of Celkeran.

Q. What is Celkeran used for?

Celkeran is used to treat some types of blood cancers like Hodgkin's disease (cancer that starts in blood cells that are part of immune system), certain forms of non-Hodgkin's lymphoma, chronic lymphocytic leukemia (disease where the bone marrow produces a large number of abnormal white cells. It is also used to treat Waldenstrom's macroglobulinaemia (rare blood condition involving the release of an abnormal protein, macroglobulin, into the blood)

Q. How is Celkeran excreted?

Celkeran is metabolized in liver to form nontoxic compounds which are excreted in urine

Q. Does Celkeran need to be refrigerated?

Celkeran has to be stored in a refrigerator at 2 °C – 8 °C

Related Products

Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1684.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 243-44.
  3. Chlorambucil. Dublin, Ireland: Aspen; 2006 [revised Mar. 2015]. [Accessed 26 Mar. 2019] (online) Available from:External Link
  4. Chlorambucil. Research Triangle Park, NC: GlaxoSmithKline; [Accessed 26 Mar. 2019] (online) Available from:External Link
  5. Medscape. Chlorambucil. [Accessed 26 Mar. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
Plot No 264, Patrika Nagar Madhapur, Hitech City Hyderabad, Telangana India - 500081
Best Price
₹1859.6
MRP2324.5  Get 20% OFF
30 tablets in 1 strip
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