Busulmax 60 Injection
Prescription RequiredProduct introduction
Busulmax 60 Injection is used in the treatment of some cancers of blood like chronic myeloid leukaemia. It is used in combination with other cancer medicines during hematopoietic progenitor cell transplantation (HPCT). It may also be used to treat some other types of cancer.
Busulmax 60 Injection is given as an injection into veins by the healthcare provider. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include decreased blood cells (red cells, white cells, and platelets), nausea, vomiting, and loss of appetite. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them.
Inform your doctor if you have a medical history, of bleeding disorders, heart or liver disease, radiation treatment or any infection. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. Inform your doctor immediately if you notice unusual bruising or bleeding or if you have dark, tarry, or bloody stools and sore throat. This medicine is known to reduce the number of blood cells in your blood thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with kidney, liver and heart function during treatment with this medicine. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Uses of Busulmax Injection
Benefits of Busulmax Injection
In Blood cancer (Chronic myeloid leukaemia)
Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body's ability to fight infection. Busulmax 60 Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
Side effects of Busulmax Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Busulmax
- Decreased blood cells (red cells, white cells, and platelets)
- Nausea
- Abdominal pain
- Vomiting
- Loss of appetite
- Anxiety
- Decreased magnesium level in blood
- Decreased potassium level in blood
- Diarrhea
- Fever
- Headache
- Increased glucose level in blood
- Insomnia (difficulty in sleeping)
- Stomatitis (Inflammation of the mouth)
How to use Busulmax Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Busulmax 60 Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Busulmax 60 Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
UNSAFE
Busulmax 60 Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
CONSULT YOUR DOCTOR
It is not known whether Busulmax 60 Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
SAFE IF PRESCRIBED
Busulmax 60 Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Busulmax 60 Injection may not be needed in these patients. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Busulmax 60 Injection in patients with liver disease. Please consult your doctor.
What if you forget to take Busulmax Injection?
If you miss a dose of Busulmax 60 Injection, contact your doctor as soon as possible. They will advise you on how to proceed, which may include rescheduling the missed dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
- Busulmax 60 Injection is given as an injection into the vein by a healthcare provider.
- Do not skip any dose and complete the course as suggested by your doctor.
- Use an effective method of birth control to avoid pregnancy while taking this medication.
- Your doctor may get regular blood tests done to monitor the levels of blood cells in your blood.
- Inform your doctor immediately if you notice unusual bruising or bleeding or if you have dark, tarry, or bloody stools and sore throat.
Fact Box
Chemical Class
Organosulfonic Acid Esters Derivative {Alkylating Agent
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Alkylating Agents
Interaction with drugs
Taking Busulmax with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Do not consume Busulfan from 1 day before until 1 day after taking Sargramostim. Please consult your doctor.
Concurrent use may cause a decrease in the ability of the bone marrow
Do not consume Lenograstim from 24 hours before until 24 hours after undergoing cytotoxic chemotherapy.
Concurrent use may cause a decrease in the ability of the bone marrow to pr
Do not consume Filgrastim from 24 hours before or 24 hours after taking Busulfan. Please consult with your doctor. Busulfan may reduce the efficacy of Filgrastim.
Do not consume Busulfan from 14 days before until 24 days after taking Pegfilgrastim. Please consult your doctor.
Concurrent use may cause a decrease in the ability of the bone ma
Do not consume Busulfan from 1 day before until 1 day after taking Molgramostim. Please consult your doctor.
Concurrent use may cause a decrease in the ability of the bone marrow
Patient concerns
FAQs
Does Busulmax 60 Injection cause hair loss?
Yes, Busulmax 60 Injection can cause hair loss.
Is Busulmax 60 Injection a vesicant?
Yes. Busulmax 60 Injection is a vesicant (irritant).
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1685-86.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 171-72.
- Busulfan. Greenville, North Carolina: DSM Pharmaceuticals, Inc.; 1999 [revised Jan. 2015]. [Accessed 26 Mar. 2019] (online) Avaialble from:
- Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Busulfan. [Updated 2018 Oct 31]. [Accessed 18 Feb. 2020] (online) Available from:
Marketer details
Name: GLS Pharma Ltd.
Address: R-4, Khirki Main Road, Malviya Nagar New Delhi- 110 017, (India)
Country of origin: India
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