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Busulfan is used in the treatment of blood cancer

How it works

Busulfan works by damaging the genetic material (DNA) of the cancer cells and stops their growth and multiplication.

Common side effects

Reduced blood platelets, Rash, Headache, Dizziness, Severe ovarian failure, Convulsion, Myelosuppression, Coordination disorder, Increased magnesium level in blood, Insomnia, Mouth ulcer, Vomiting, Weakness, Sleepiness, Liver injury, Delayed puberty, Pneumonitis, Nausea, Decreased potassium level in blood, Abdominal pain, Infection, Premature menopause, Loss of appetite, Bone-marrow suppression, Brain swelling, Decreased white blood cell count, Cns toxicity, Suppression of spermatogenesis, Hair loss, Absence of menstrual periods, Jaundice, Fatigue, Fever, Anxiety, Increased liver enzymes, Anemia, Decreased blood cells (red cells, white cells, and platelets), Hallucination, Thrombophlebitis, Impotence, Blood in urine, Diarrhoea, Depression, Vertigo, Speech disorder, Confusion, Mucosal inflammation, Drowsiness, Gastritis, Decreased white blood cell count (neutrophils), Dark skin patches, Difficulty in urination, Constipation, Heart beat irregular, Stomatitis, Hemiparesis (weakness on one side of the body), Uncoordinated body movements, Leukemia, Viral infection, Decreased white blood cell count (lymphocytes), Increased glucose level in blood, Hemiplegia (paralysis of one side of the body)

Available Medicine

No medicine available

Expert advice

  • Seek immediate medical attention if you have unusual bruising or bleeding, or signs of infection (fever, chills, body aches) as busulfan can lower the ability of your blood to clot and body to fight infections.
  • Inform your doctor if you have thalassemia (abnormal hemoglobin in blood), gout (arthritis due to impaired metabolism of uric acid) or if you have had radiotherapy.
  • Do not receive live vaccine while using busulfan, and avoid contact with individuals who have recently received the same.
  • Tell your doctor if you are or planning to become pregnant or are breastfeeding.
  • Common Side Effects.

Frequently asked questions



Does busulfan cause hair loss?
Busulfan can cause hair loss


Is busulfan a vesicant?
Yes. Busulfan is a vesicant (irritant).

Content on this page was last updated on 23 February, 2017, by Dr. Varun Gupta (MD Pharmacology)