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Bufatas IV 6mg Injection

Busulfan (6mg)
Genuine
Authenticity Assured
Prescription
required
Cold stored
Stored between 2-8°C
Bufatas IV 6mg Injection is used in the treatment of some cancers of blood like chronic myeloid leukaemia. It is used in combination with other cancer medicines during hematopoietic progenitor cell transplantation (HPCT). It may also be used to treat some other types of cancer.

Written By Dr. Subita Alagh, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 17 Jul 2026 | 01:03 AM (IST)
₹8894 MRP ₹1057516% off 
 
 
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Bufatas IV 6mg Injection
Bufatas IV 6mg Injection
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BU Stim 6mg Injection
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General Information

Contains

Busulfan (6mg)

Marketer

Intas Pharmaceuticals Ltd

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.
The content is shown in English
Bufatas IV 6mg Injection image
Bufatas IV 6mg Injection image

Product introduction

Bufatas IV 6mg Injection is given as an injection into veins by the healthcare provider. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include decreased blood cells (red cells, white cells, and platelets), nausea, vomiting, and loss of appetite. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them.

Inform your doctor if you have a medical history, of bleeding disorders, heart or liver disease, radiation treatment or any infection. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using.  Inform your doctor immediately if you notice unusual bruising or bleeding or if you have dark, tarry, or bloody stools and sore throat. This medicine is known to reduce the number of blood cells in your blood thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with kidney, liver and heart function during treatment with this medicine. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Bufatas Injection

Benefits of Bufatas Injection

Blood cancer (Chronic myeloid leukaemia)
Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body's ability to fight infection. Bufatas IV 6mg Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Side effects of Bufatas Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Bufatas
  • Decreased magnesium level in blood
  • Decreased blood cells (red cells, white cells, and platelets)
  • Nausea
  • Abdominal pain
  • Vomiting
  • Loss of appetite
  • Anxiety
  • Decreased potassium level in blood
  • Diarrhea
  • Fever
  • Headache
  • Increased glucose level in blood
  • Insomnia (difficulty in sleeping)
  • Stomatitis (Inflammation of the mouth)

How to use Bufatas Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Bufatas Injection works

Bufatas IV 6mg Injection works by damaging the DNA of rapidly dividing cells, especially cancerous blood cells in the bone marrow. This stops these abnormal cells from growing and multiplying. It reduces the number of cancer cells produced in the bone marrow, this medicine helps control chronic myeloid leukaemia and slows the progression of the disease.

All substitutes for Bufatas IV 6mg Injection

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

  • Bufatas IV 6mg Injection is given as an injection into the vein by a healthcare provider.
  • Do not skip any dose and complete the course as suggested by your doctor.
  • Use an effective method of birth control to avoid pregnancy while taking this medication.
  • Your doctor may get regular blood tests done to monitor the levels of blood cells in your blood.
  • Inform your doctor immediately if you notice unusual bruising or bleeding or if you have dark, tarry, or bloody stools and sore throat.
     

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Bufatas IV 6mg Injection. Please consult your doctor.
Pregnancy

Pregnancy

UNSAFE
Bufatas IV 6mg Injection is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.
Breast feeding

Breast feeding

UNSAFE
Bufatas IV 6mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving

Driving

SAFE
Bufatas IV 6mg Injection does not usually affect your ability to drive.
Kidney

Kidney

CONSULT YOUR DOCTOR
There is limited data available on the use of Bufatas IV 6mg Injection in patients with kidney disease. Please consult your doctor.
Liver

Liver

CAUTION
Bufatas IV 6mg Injection should be used with caution in patients with severe liver disease. Dose adjustment may be needed.
All

Interaction with drugs

Taking Bufatas with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Pegfilgrastim (Injection Route)

Do not consume Busulfan from 14 days before until 24 days after taking Pegfilgrastim. Please consult your doctor.
Severe

Sargramostim (Injection Route)

Do not consume Busulfan from 1 day before until 1 day after taking Sargramostim. Please consult your doctor.
Severe

Lenograstim (Injection Route)

Do not consume Lenograstim from 24 hours before until 24 hours after undergoing cytotoxic chemotherapy.
Severe

Molgramostim (Injection Route)

Do not consume Busulfan from 1 day before until 1 day after taking Molgramostim. Please consult your doctor.
Severe

Natalizumab (Injection Route)

Do not consume Natalizumab with Busulfan.

Frequently asked questions

Yes, Bufatas IV 6mg Injection can cause hair loss.
Yes. Bufatas IV 6mg Injection is a vesicant (irritant).

Fact Box

Chemical Class

Organosulfonic acid esters

Habit Forming

No

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Alkylating Agents

References

  1. Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1685-86.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 171-72.
  3. Busulfan. Greenville, North Carolina: DSM Pharmaceuticals, Inc.; 1999 [revised Jan. 2015]. [Accessed 26 Mar. 2019] (online) Avaialble from:
  4. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Busulfan. [Updated 2018 Oct 31]. [Accessed 18 Feb. 2020] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Intas Pharmaceuticals Ltd
Address: Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.

Vendor Details

Country of origin: India
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