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Bleochem 15IU Injection

Written By Dr. Subita Alagh, BDS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 23 Dec 2025 | 11:04 PM (IST)
Bleochem 15IU Injection is a medicine used for treatment of cancer in various parts of the body such as cervical, cancer of the mouth, nasopharynx and paranasal sinuses, larynx, esophagus, and skin. It works by interfering with the growth of cancer cells, which are eventually destroyed.
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General Information

Contains

Bleomycin (15IU)

Marketer

Biochem Pharmaceutical Industries

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.
The content is shown in English
Bleochem 15IU Injection image
Bleochem 15IU Injection image

Product introduction

Bleochem 15IU Injection may be used alone or with other medicines as part of combination therapy. It is given under the supervision of a healthcare professional and should not be self-administered. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. You should avoid drinking alcohol as it may increase your risk of liver damage.

The most common side effects of this medicine include fever, loss of appetite, loss of hair, weight loss, nausea, inflammation of the lungs (interstitial pneumonia), shortness of breath or cough. If they do not go away or get worse, tell your doctor. There may be ways of preventing or reducing these effects. It is very strong medicine and some people may develop serious side effects while taking it. This medicine may lower your ability to fight infections and lead to problems with your blood, liver or kidneys. Your doctor will advise you regular blood tests to check for these.

Before taking it, tell your doctor if you have stomach, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. It may harm your baby. You and your partner should avoid becoming pregnant or fathering a child for several months after your treatment with it has stopped. Your doctor may perform several tests such as blood tests, X-rays and physical examinations both before and during treatment with this medicine.

Uses of Bleochem Injection

Benefits of Bleochem Injection

Cervical cancer
Bleochem 15IU Injection is an anti-cancer medicine that is used to kill cancerous cells in various kinds of cancer such as cervical cancer, cancer of mouth, nasopharynx and paranasal sinuses, larynx, oesophagus and skin cancer. It may be given alone or in combination with other medicines. It has a lot of side effects and you must discuss the risks and benefits with your doctor before starting treatment with this medicine. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Side effects of Bleochem Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Bleochem
  • Fever
  • Hair loss
  • Interstitial pneumonia
  • Loss of appetite
  • Low blood platelets
  • Nail discoloration
  • Nausea
  • Pulmonary fibrosis
  • Rigors
  • Scratch dermatitis
  • Skin pigmentation
  • Stomatitis (Inflammation of the mouth)
  • Vomiting
  • Weight loss

How to use Bleochem Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Bleochem Injection works

Bleochem 15IU Injection is an anti-cancer medication. It works by damaging the genetic material (DNA) of the cancer cells and stops their growth and multiplication.

All substitutes for Bleochem 15IU Injection

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

  • Bleochem 15IU Injection is given as an injection into the veins, muscles or under the skin by the healthcare provider.
  • Do not skip any dose and complete the course as suggested by your doctor.
  • Use an effective method of birth control to avoid pregnancy while taking this medication.
  • You may need to have blood tests to monitor your blood cells, liver function and kidney function during treatment.
  • Inform your doctor immediately if you experience coughing, shortness of breath and cracking sound while breathing.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Bleochem 15IU Injection. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Bleochem 15IU Injection is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Bleochem 15IU Injection may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

UNSAFE
Bleochem 15IU Injection may cause side effects that could affect your ability to drive.
Some have reported of feeling tired or weak after the treatment, avoid driving if you experience such symptoms.
Kidney

Kidney

CAUTION
Bleochem 15IU Injection should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Liver

Liver

SAFE IF PRESCRIBED
Bleochem 15IU Injection is probably safe to use in patients with liver disease. Limited data suggest dose adjustment may not be needed.

Interaction with drugs

Taking Bleochem with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Cholera Vaccine (Inactivated) (Oral Route)

Do not use Bleomycin with Cholera Vaccine (Inactivated). If Bleomycin is essential, ensure a gap of At least 6 months after discontinuing Cholera Vaccine (Inactivated). Please consult your doctor.
Severe

Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted) (Injection Route)

Do not use Bleomycin with Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted). If Bleomycin is essential, ensure a gap of At least 6 months after discontinuing Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted). Please consult your doctor.
Severe

Purified Vi Polysaccharide Typhoid Vaccine (Injection Route)

Do not use Bleomycin with Purified Vi Polysaccharide Typhoid Vaccine. If Bleomycin is essential, ensure a gap of At least 6 months after discontinuing Purified Vi Polysaccharide Typhoid Vaccine. Please consult your doctor.
Severe

Natalizumab (Injection Route)

Do not consume Natalizumab with Bleomycin.
Moderate

Digoxin (Oral Route)

Please consult your doctor for dose-related advice. Digoxin may raise blood levels of the active form of Bleomycin.

Frequently asked questions

Bleochem 15IU Injection is used to treat squamous cell cancers, certain types of blood cancers, skin cancers and cancer of the thyroid, bladder, lungs, abdomen or genitals.
Yes. Bleochem 15IU Injection may cause pulmonary fibrosis, nausea and hair loss. If you notice any such symptoms, please consult your doctor.
Pulmonary fibrosis (scarring of the tissue of the lungs) is one of the side effects of Bleochem 15IU Injection. It is reportedly caused by lack of an enzyme that metabolises Bleochem 15IU Injection in the lungs.

Fact Box

Chemical Class

Hybrid glycopeptides

Habit Forming

No

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Cytotoxic Alkaloids

References

  1. Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1716-18.
  2. Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 952-53.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 149-50.
  4. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Bleomycin. [Updated 2018 Dec 3]. [Accessed 18 Feb. 2020] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Biochem Pharmaceutical Industries
Address: BIOCHEM PHARMA, LG 113 / A, Xth Central Mall, Mahavir Nagar, 90ft Road, Next to D Mart, Kandivali - West, Mumbai - 400067.

Vendor Details

Country of origin: India
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