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18 Feb 2020 | 05:25 PM (IST)
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Bioglandin 500mcg Injection

Prescription Required
Store in a refrigerator (2 - 8°C). Do not freeze.



Bioglandin 500mcg Injection is used to treat erectile dysfunction (inability to maintain erection for intercourse) in men. It increases blood flow in the penis on sexual stimulation to achieve and maintain an erection suitable for sexual activity.

Bioglandin 500mcg Injection is a prescription medicine that is to be taken only with a valid doctor’s prescription. It is very important to read the label before taking the medicine for an accurate administration of the injection. The medicine is to be taken before you plan any sexual activity. It must be used as per the label or as guided by the doctor. You must receive the medicine in the dose and duration as per the prescription. Long-term use of this medicine is not recommended unless your doctor asks you to do so.

This medicine is usually safe, but it may cause pain at the site of injection (penis pain) and prolonged erection. If you experience any other side effects inform the doctor without delay.

Before receiving the treatment, inform your doctor if you are on any medication for any other health condition. Patients with heart or blood pressure disorder must be cautious while receiving the prescription and they must receive regular follow-ups as per the doctor’s advice.

Uses of Bioglandin Injection

  • Patent ductus arteriosus (PDA)

Side effects of Bioglandin Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Bioglandin

  • Injection site pain
  • Arrhythmia (irregular heartbeats)
  • Apnea (absence of breathing)
  • Diarrhea
  • Fever
  • Flushing (sense of warmth in the face, ears, neck and trunk)
  • Seizure
  • Sepsis

How to cope with side effects?

The occurrence of side effects varies from person to person. The following are a few ways of dealing with some of the common side effects. However, consult your doctor if these persist.

  • Coping with Injection site pain
    Try to change the area of injection and the exact site of injection each time. Apply a cold compress to the injection site. These symptoms are usually mild and should only last a few hours. You can ask your doctor to recommend a medicine if it is bothering you.
  • Coping with Arrhythmia (irregular heartbeats)
    Changes to your heart rhythm can be treated with a variety of medicines. You should ask your doctor whether you need medication or not. You can also try to prevent arrhythmias by limiting the amount of alcohol you drink and quitting smoking. Cut down the amount of coffee, tea or cola you drink. Lose weight if you need to. In general, keeping active, eating a healthy well-balanced diet, and having your blood pressure and cholesterol level under control is good for any heart condition. Your doctor will probably want you to get follow-up tests while taking this medicine and advise you accordingly.
  • Coping with Diarrhea
    Keep up your intake of fluids and electrolytes (sugars and salts) to avoid getting dehydrated. Eat less fiber (avoid raw fruits, fruit juice and vegetables). Talk to your doctor about possible medication to manage diarrhea. Ask about reducing the dosage of your drug or other suitable treatments.
  • Coping with Flushing (sense of warmth in the face, ears, neck and trunk)
    Sip cold or iced drinks. Try cutting down on coffee, tea and alcohol. It might help to keep the room cool and use a fan. You could also spray cool water on your face. Wear layers of light clothing that you can easily take off if you overheat. Breathe deeply and try to relax. Have a lukewarm shower or bath instead of a hot one. Avoid smoking and cut down on alcohol. The flushing should go away after a few days. If it does not go away or causes problems, contact your doctor. There may be medicines that can help.
  • Coping with Seizure
    Having a fit or seizure can be dangerous. It often needs urgent medical help. Do not stop taking this medicine suddenly. Ask your doctor about gradually reducing the dose of your medicine or stopping the treatment. You can help yourself avoid having a seizure by taking your medicine in the right doses at the right time(s). Make sure you get enough sleep, as lack of sleep can trigger a seizure. Keep active and manage your stress levels.

How to use Bioglandin Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Bioglandin Injection works

Bioglandin 500mcg Injection is similar to a natural substance in the body called prostaglandin E1. It works by improving blood flow in newborn babies born with heart defects. When it is administered in the penis, it acts locally to relax the blood vessels and increases blood flow in the penis. This results in prolonged persistence of the penile erection that is adequate for sexual activity.

Safety Advice

It is not known whether it is safe to consume alcohol with Bioglandin 500mcg Injection. Please consult your doctor.
Bioglandin 500mcg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Information regarding the use of Bioglandin 500mcg Injection during breastfeeding is not available. Please consult your doctor.
Bioglandin 500mcg Injection may cause side effects which could affect your ability to drive.
Bioglandin 500mcg Injection may make you feel dizzy or faint. This may affect your driving ability.
There is limited information available on the use of Bioglandin 500mcg Injection in patients with kidney disease. Please consult your doctor.
There is limited information available on the use of Bioglandin 500mcg Injection in patients with liver disease. Please consult your doctor.

What if you forget to take Bioglandin Injection?

If you miss a dose of Bioglandin 500mcg Injection, please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Bioglandin 500mcg Injection
₹106.31/ml of Injection
save 98%
Prostal Injection
Celon Laboratories Ltd
₹5517/ml of Injection
save 6%
Alpostin 500mcg Injection
Samarth Life Sciences Pvt Ltd
₹6663.28/ml of Injection
14% costlier
₹9000/ml of Injection
54% costlier

Quick Tips

  • Bioglandin 500mcg Injection helps to keep a blood vessel called the ductus arteriosus open in babies born with a heart defect, until the defect can be corrected with surgery.
  • It is given into one of the baby's veins using a drip (intravenous infusion).
  • It is administered only by well trained healthcare professionals and in facilities with immediate access to paediatric intensive care.

Fact Box

Chemical Class
Prostaglandin E1 (PGE1) Analogue
Habit Forming

Patient Concerns

Actually my baby is 1 month and 15 days. Two holes detect in heart of my baby from birth. Her weight is 3 kg at present and 2.5 kg birth time. So please suggest we should what to do.
Dr. Nabajit Talukdar
Currently nothing review echo after 3 months n see d status of pda
Which medicine we use. In PDA
Dr. Saurabh Arora
No medicine per say symptoms relieve only get it closed
Do you have any questions related to Bioglandin 500mcg Injection ?

User Feedback


Q. Is Bioglandin safe/ why does Bioglandin cause apnea?

Bioglandin is safe if used at recommended dosage and duration. Apnea is not reported as side effect when used for the treatment of erectile dysfunction. Always consult your doctor before its use

Q. How effective is Bioglandin/ does Bioglandin work/ does Bioglandin gel work?

Bioglandin is effective if used at recommended dosage and duration as advised by your doctor

Q. How is Bioglandin administered?

Bioglandin is either injected into the penis or used as a urethral suppository (pellet to be placed into the urinary opening of the penis). Consult your doctor regarding administration of alprostadi

Q. How is Bioglandin stored?

Bioglandin injections (with suspensions) can be stored below or at 25°C for 24 hrs. Urethral stick in unopened pouches is stored in a refrigerator (2-8oC). Prior to use you may remove them from the refrigerator and store them at room temperature (not above 30oC) for a maximum of 14 days.

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1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.


  1. Smyth EM, Grosser T, FitzGerald GA. Lipid-Derived Autacoids: Eicosanoids and Platelet-Activating Factor. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 952.
  2. Smyth EM, FitzGerald GA. The Eicosanoids: Prostaglandins, Tromboxanes, Leukotriens, & Related Compounds. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 325-26.
  3. Alprostadil. [Accessed 04 Apr. 2019] (online) Available from:External Link
  4. Alprostadil. Sandwich, Kent: 2010 [revised Mar. 2017]. [Accessed 04 Apr. 2019] (online) Available from:External Link
  5. Alprostadil. Chesterbrook, Pennsylvania: Auxilium Pharmaceuticals, Inc.; 2015. [Accessed 01 Feb. 2019] (online) Available from:External Link

Manufacturer/Marketer Address

FC/B-1 (Extn.), Mohan Co-operative Industrial Estate Mathura Road, New Delhi - 110 044
Country of Origin: India
Best Price
MRP5850  Get 15% OFF
1 Injection in 1 vial


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