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MMST, MBBS
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MD (Pharmacology), MBBS
Last updated
28 Dec 2022 | 11:09 AM (IST)

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Prostal Injection

Prescription Required
Manufacturer/ Marketer
SALT COMPOSITION
Storage
Store in a refrigerator (2 - 8°C). Do not freeze.

Product introduction

Prostal Injection is used to treat patent ductus arteriosus (PDA), a heart defect that occurs in newborns. It improves blood circulation in such babies and helps treat this defect.

Prostal Injection is given as an injection by a doctor or nurse and should not be used without medical supervision. The most common side effects of this medicine are interrupted breathing (apnea) and a high temperature for a short time period (transient pyrexia/fever). If your baby has these or any other side effects, let your doctor know.

All babies can have Prostal Injection if they need it. The doctor will carry out tests before deciding whether to give this medicine to your baby. However, if your baby develops any signs of allergy to this medicine, such as wheezing, breathlessness, swelling of the face, hands, itchy rash, or redness of the skin, it is advised to not use this medicine. Consult your doctor if you have any doubts.

Uses of Prostal Injection

  • Treatment of Patent ductus arteriosus (PDA)

Benefits of Prostal Injection

In Treatment of Patent ductus arteriosus (PDA)

Patent ductus arteriosus (PDA) is a persistent opening between the two major blood vessels leading from the heart. Usually this opening closes shortly after birth, but it can remain open and lead to this heart defect in babies. Prostal Injection improves blood flow in such babies who have PDA. It is given as an injection by a doctor or nurse in a hospital setup. Follow your doctor’s instructions carefully to get the most benefit.

Side effects of Prostal Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Prostal

  • Apnea (absence of breathing)
  • Fever

How to use Prostal Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Prostal Injection works

Prostal Injection is similar to a natural substance in the body called prostaglandin E1. It works by improving blood flow in newborn babies born with heart defects.

Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Prostal Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Information regarding the use of Prostal Injection during pregnancy is not available. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Prostal Injection during breastfeeding is not available. Please consult your doctor.
Driving
CONSULT YOUR DOCTOR
It is not known whether Prostal Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Prostal Injection in patients with kidney disease. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Prostal Injection in patients with liver disease. Please consult your doctor.

What if you forget to take Prostal Injection?

If you miss a dose of Prostal Injection, please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Prostal Injection
₹5186/Injection
₹106.31/injection
98% cheaper
₹5650/injection
2% costlier
Bioglandin 500mcg Injection
United Biotech Pvt Ltd
₹5850/injection
6% costlier
Alpostin 500mcg Injection
Samarth Life Sciences Pvt Ltd
₹6372/injection
16% costlier
₹9000/injection
63% costlier

Fact Box

Chemical Class
Prostaglandin E1 (PGE1) Analogue
Habit Forming
No
Therapeutic Class
CARDIAC
Action Class
Prostaglandin E1 (PGE1) analogue- ED

Patient concerns

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Actually my baby is 1 month and 15 days. Two holes detect in heart of my baby from birth. Her weight is 3 kg at present and 2.5 kg birth time. So please suggest we should what to do.
Dr. Nabajit Talukdar
Cardiology
Currently nothing review echo after 3 months n see d status of pda
Which medicine we use. In PDA
Dr. Saurabh Arora
Cardiology
No medicine per say symptoms relieve only get it closed
arrow

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Smyth EM, Grosser T, FitzGerald GA. Lipid-Derived Autacoids: Eicosanoids and Platelet-Activating Factor. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 952.
  2. Smyth EM, FitzGerald GA. The Eicosanoids: Prostaglandins, Tromboxanes, Leukotriens, & Related Compounds. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 325-26.
  3. Alprostadil [EMC SmPC]. Sandwich, Kent: Pfizer Limited; 2019. [Accessed 03 Mar. 2021] (online) Available from: External Link
  4. Drugs.com. Alprostadil. [Accessed 04 Apr. 2019] (online) Available from:External Link

Manufacturer/Marketer address

Plot No 264, Patrika Nagar Madhapur, Hitech City Hyderabad, Telangana India - 500081
Country of origin: India
5186
Inclusive of all taxes
MRP5517  6% OFF
1 ml in 1 vial
SOLD OUT
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