Information about Alprostadil

Alprostadil Uses

Alprostadil is used in the treatment of patent ductus arteriosus. It may also be used in the treatment of erectile dysfunction.

How Alprostadil works

Alprostadil is similar to a natural substance in the body called prostaglandin E1. It works by improving blood flow in newborn babies born with heart defects. When it is administered in the penis, it acts locally to relax the blood vessels and increases blood flow in the penis. This results in prolonged persistence of the penile erection that is adequate for sexual activity.

Common side effects of Alprostadil

Apnea (absence of breathing), Fever, Seizure, Flushing (sense of warmth in the face, ears, neck and trunk), Arrhythmia (irregular heartbeats), Diarrhea, Sepsis
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Reviewed By
MD (Pharmacology), MBBS
Last updated
02 Mar 2021 | 11:22 AM (UTC)

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Available Medicine for Alprostadil

AlpostinSamarth Life Sciences Pvt Ltd
63721 variant(s)
BioglandinUnited Biotech Pvt Ltd
58501 variant(s)
Prostin VRMax India Ltd
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Expert advice for Alprostadil

  • Alprostadil helps to keep a blood vessel called the ductus arteriosus open in babies born with a heart defect, until the defect can be corrected with surgery.
  • It is given into one of the baby's veins using a drip (intravenous infusion).
  • It is administered only by well trained healthcare professionals and in facilities with immediate access to paediatric intensive care.

Frequently asked questions for Alprostadil


Q. Is Alprostadil safe? Does it cause apnea?

Alprostadil is safe if used at recommended dosage and duration. Apnea is not reported as side effect when used for the treatment of erectile dysfunction. Always consult your doctor before its use.

Q. How is Alprostadil administered?

Alprostadil is either injected into the penis or used as a urethral suppository (pellet to be placed into the urinary opening of the penis). Consult your doctor regarding administration of Alprostadil.

Q. How is Alprostadil stored?

Alprostadil injections (with suspensions) can be stored below or at 25°C for 24 hrs. Urethral stick in unopened pouches is stored in a refrigerator (2-8oC). Prior to use you may remove them from the refrigerator and store them at room temperature (not above 30oC) for a maximum of 14 days.


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