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Benzonix Gel is a topical medicine used for the treatment of acne vulgaris. It works by killing acne-causing bacteria on the skin and by helping to remove dead skin cells that block pores. This reduces the formation of pimples and blackheads and helps keep the skin clearer over time.

Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 29 Apr 2026 | 01:02 PM (IST)
₹56.8 MRP ₹6614% off 
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Benzonix Gel image
Benzonix Gel image

Product introduction

Use Benzonix Gel in the exact dose and duration prescribed by your doctor or follow the instructions provided in the leaflet. Wash and dry the affected area before application. It may take several weeks for your symptoms to improve. Keep using it as advised. Consult your doctor if your condition does not improve after a month of regular use.


Common side effects of Benzonix Gel include itching, stinging, peeling, and redness of the skin. They are not usually serious, but tell your doctor if they bother you or do not go away. You may need to apply a smaller amount or use it less often. It can also bleach hair and fabrics, including clothes, so be careful to avoid contact with these.


Benzonix Gel is meant for external use only and should be applied carefully to avoid irritation. Do not apply the medicine to broken or damaged skin. Also, keep the medicine away from the eyes, mouth, nose, and other sensitive areas. Sun exposure and UV light should be limited during treatment, as the skin becomes more sensitive to sunlight.

Uses of Benzonix Gel

Benefits of Benzonix Gel

Acne
Benzonix Gel is an antimicrobial agent that treats acne, commonly called pimples. It kills the acne-causing bacteria and prevents spots or pimples from appearing. It usually takes a few weeks to have a noticeable effect so keep using it even if it appears not to be working. Sometimes acne may get worse before it gets better, however, with proper use, your skin will get clearer. The earlier you start using it, the less likely you are to get scars. This medicine will help improve your mood and uplift your confidence as your skin becomes acne-free. It should not be used if you have eczema or sunburned skin.

Side effects of Benzonix Gel

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Benzonix
  • Dry skin
  • Erythema (skin redness)
  • Burning sensation
  • Itching
  • Skin irritation
  • Skin pain
  • Skin exfoliation

How to use Benzonix Gel

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the gel. Wash your hands after applying, unless hands are the affected area.

How Benzonix Gel works

Benzonix Gel works by releasing oxygen into the skin, which helps kill the bacteria involved in acne. It also helps loosen and remove dead skin cells that block pores, reducing the formation of pimples and blackheads and supporting clearer skin.

Quick tips

  • Do a small test on one or two spots for the first 3 days.
  • Start once daily and increase gradually only if needed and tolerated.
  • Avoid using other topical acne products on the same area unless your doctor advises.
  • Reduce to once daily or every other day if your skin becomes very dry or irritated.
  • Do not apply Benzonix Gel to sunburned or damaged skin.

Safety advice

Alcohol

Alcohol

No interaction found/established
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Benzonix Gel during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

SAFE IF PRESCRIBED
Benzonix Gel may be safe to use during breastfeeding. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Driving

Driving

No interaction found/established
Kidney

Kidney

No interaction found/established
Liver

Liver

No interaction found/established

Frequently asked questions

You should remove all of the make-up. Wash your hands and the affected area and gently dry. Put a thin layer of Benzonix Gel cream on the affected skin, using your fingertips. Apply it to the entire area affected by acne, not just each spot. After applying, wash your hands thoroughly with water.
The initial dose is preferably once daily in the evening. Later, the doctor will gradually increase the dose to twice daily (most probably morning and evening).
Benzonix Gel is usually applied once a day in the evening when starting treatment. After applying it, the area does not need to be washed off, so it can be left on overnight. If you notice significant irritation or discomfort, stop using it and consult your doctor.
You may see an improvement after 4-6 weeks of treatment. You may need to use this treatment for longer to see the full benefits. This is normal for acne treatments. If your acne does not get better after 1 month or if it gets worse, talk to your doctor immediately.
You may apply moisturizer an hour after applying Benzonix Gel. Consult your doctor in case of any doubt or concern.
You should discontinue Benzonix Gel and consult your doctor if you experience severe local irritation, which means severe redness, dryness and itching and stinging/burning sensation.
Use Benzonix Gel only on your skin. Keep it away from areas like your eyes, eyelids, lips, mouth and inside of the nose. If the medicine comes in contact with any of these areas, wash the affected area with water immediately. Avoid using Benzonix Gel on scratched or eroded skin and open wounds. Benzonix Gel can also make your skin more sensitive to sunlight. So, avoid the use of sunbeds/lamps and minimize the time you spend in the sun. Use sunscreen and wear protective clothing while using Benzonix Gel. Avoid contact with hair, clothes, and furniture as Benzonix Gel has bleaching properties.
You should remove all of the make-up. Wash your hands and the affected area and gently dry. Put a thin layer of Benzonix Gel cream on the affected skin, using your fingertips. Apply it to the entire area affected by acne, not just each spot. After applying, wash your hands thoroughly with water.
At the beginning of the treatment, Benzonix Gel is usually used once daily in the evening. The area is not washed off after application of Benzonix Gel, so it can be left overnight unless you experience irritation. However, if you experience irritation, consult your doctor.
You should discontinue Benzonix Gel and consult your doctor if you experience severe local irritation, which means severe redness, dryness and itching and stinging/burning sensation.
Use Benzonix Gel only on your skin. Keep it away from areas like your eyes, eyelids, lips, mouth and inside of the nose. If the medicine comes in contact with any of these areas, wash the affected area with water immediately. Avoid using Benzonix Gel on scratched or eroded skin and open wounds. Take care when using Benzonix Gel on sensitive areas of skin such as your neck. Benzonix Gel can make your skin more sensitive to the harmful effects of the sunlight. So, avoid the use of sunbeds/lamps and minimize the time you spend in the sun. You should use sunscreen and wear protective clothing while using Benzonix Gel. Avoid contact with hair as Benzonix Gel has bleaching properties. It can even bleach dyed or colored fabric, furniture or carpeting.
The initial dose is preferably once daily in the evening. Later, the doctor will gradually increase the dose to twice daily (most probably morning and evening).
You may see an improvement after 4-6 weeks of treatment. You may need to use this treatment for longer to see the full benefits. This is normal for acne treatments. If your acne does not get better after 1 month or if it gets worse, talk to your doctor immediately.
You may apply moisturizer an hour after applying Benzonix Gel. Consult your doctor in case of any doubt or concern.

Fact Box

Chemical Class

Benzoyl peroxides

Habit Forming

No

Therapeutic Class

DERMA

Action Class

Keratoplastic and Keratolytic Agents

References

  1. Robertson DB, Maibach HI. Dermatologic Pharmacology. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 1056-57.
  2. Sardana K, Madan A. How to Treat Acne. Sardana K, editor. In: Clinical Approach to Acne Vulgaris. 1st ed. New Delhi: CBS Publishers & Distributors Pvt. Ltd.; 2015. pp. 31-32.
  3. Benzoyl Peroxide [Product Information]. Minneapolis, MN: Padagis Israel Pharmaceuticals Ltd.; 2024.
  4. Benzoyl Peroxide [EMC SmPC]. London, England: Galderma (UK) Limited; 2023. [Accessed 15 Jan. 2026] (online) Available from:
  5. Central Drugs Standard Control Organisation (CDSCO): Benzoyl Peroxide. [Accessed 15 Jan. 2026] (online) Available from:
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User feedback

Once A Day
100%
Acne
86%
Others
14%
Average
100%
No Side Effect
100%
Average
100%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Canixa Life Sciences Pvt Ltd
Address: K. No. 312 & 313, Raipur Industrial Area, Bhagawanpur Roorkee, Dist. Haridwar, Uttarakhand

Vendor Details

Country of origin: India
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