Axzyb Tablet

Written By Dr. Subita Alagh, BDS

Reviewed By Dr. Rajeev Sharma, MBA, MBBS

Last updated on 30 Jan 2026 | 03:40 PM (IST)

Axzyb Tablet is an anti-cancer medicine used in the treatment of kidney cancer.

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₹3587 MRP ₹3937.59% off

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Same composition alternative:

Inlyta 5mg Tablet

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Axzyb Tablet

bottle of 30 tablets

₹3587

~~₹3937.5~~

Same composition

Inlyta 5mg Tablet

box of 28 tablets

Axitinib (5mg)

by Pfizer Ltd

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₹68475

₹2445.54 per tablet

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General Information

Contains

Axitinib (5mg)

Marketer

Glenmark Pharmaceuticals Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Axzyb Tablet can be taken with or without food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include high blood pressure, joint pain, and loss of appetite. Diarrhea, shortness of breath, can be serious sometimes so take medicine to treat it as prescribed by the doctor or stay hydrated. Your doctor may advise for regular blood pressure checkups while you are taking this medicine. Inform your doctor if you notice a severe headache, confusion, problems with your eyesight, nausea or vomiting.

Before taking it, tell your doctor if you have thyroid problems, liver or bleeding problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by females during treatment is important to avoid pregnancy.

Uses of Axzyb Tablet

Kidney cancer

Benefits of Axzyb Tablet

Kidney cancer
Kidney cancer occurs when abnormal cells in the kidneys grow uncontrollably, often forming a tumor that can interfere with kidney function and spread to other organs. Axzyb Tablet works by slowing the growth of cancer cells and reducing the blood supply to the tumor. It helps control tumor progression, relieves symptoms, and improves survival outcomes in patients with advanced kidney cancer.

Side effects of Axzyb Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Axzyb

Dizziness
Nausea
Dry skin
Vomiting
Constipation
Decreased appetite
Muscle pain
Anemia (low number of red blood cells)
Headache
Weight loss
Weakness
Nosebleeds
Ringing in ear
Diarrhea
Voice change
Palmar-plantar erythrodysesthesia syndrome
Increased creatinine level in blood
Low bicarbonate levels in blood
Increased lipase in the blood
Elevated levels of serum amylase
Decreased calcium level in blood
Upper abdominal pain
Dehydration
Piles
Blood in urine
Pulmonary embolism
Rectal bleeding
Breathlessness
Fatigue
High blood pressure

How to use Axzyb Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Axzyb Tablet may be taken with or without food.

How Axzyb Tablet works

Axzyb Tablet is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.

All substitutes for Axzyb Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Take it with or without food, preferably at the same time each day.
Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if it doesn't stop or if you find blood in your stools.
Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for a month after you stop taking it.
Monitor your blood pressure regularly while taking this medication. Inform your doctor if you notice symptoms of very high blood pressure such as severe headache, confusion, problems with your eyesight, nausea or vomiting.
It may cause serious bleeding problem. Inform your doctor if you get headaches, stomach pain or if you notice blood in your urine or stools.
Do not take this medicine if you are pregnant, planning to conceive or breastfeeding.
Take it with or without food, preferably at the same time each day.
Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if it doesn't stop or if you find blood in your stools.
Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for a month after you stop taking it.
Monitor your blood pressure regularly while taking this medication. Inform your doctor if you notice symptoms of very high blood pressure such as severe headache, confusion, problems with your eyesight, nausea or vomiting.
It may cause serious bleeding problem. Inform your doctor if you get headaches, stomach pain or if you notice blood in your urine or stools.
Do not take this medicine if you are pregnant, planning to conceive or breastfeeding.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Axzyb Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Axzyb Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CONSULT YOUR DOCTOR

Axzyb Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

UNSAFE

Axzyb Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

SAFE IF PRESCRIBED

Axzyb Tablet is safe to use in patients with kidney disease. No dose adjustment is recommended.

Liver

CONSULT YOUR DOCTOR

There is limited data available on the use of Axzyb Tablet in patients with liver disease.
Limited information is available on the use of Axzyb Tablet in patients with the severe liver disease.

Interaction with drugs

Taking Axzyb with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Life-threatening

Acenocoumarol (Oral Route)

If concurrent use is essential, watch out for bleeding and consult your doctor immediately. Your doctor may frequently monitor your blood clotting time.

Life-threatening

Phenindione (Oral Route)

If concurrent use is essential, watch out for bleeding and consult your doctor immediately. Your doctor may frequently monitor your blood clotting time.

Life-threatening

Warfarin (Oral Route)

If concurrent use is essential, watch out for bleeding and consult your doctor immediately. Your doctor may frequently monitor your blood clotting time.

Severe

Atazanavir (Oral Route)

Atazanavir may raise blood levels of Axitinib. Atazanavir may raise blood levels of Axitinib.

Severe

Bosentan (Oral Route)

Bosentan may reduce blood levels of Axitinib. Bosentan may reduce blood levels of Axitinib.

Frequently asked questions

What are the possible signs and symptoms of kidney cancer?

Some possible signs and symptoms of kidney cancer include blood in the urine (hematuria) which may appear dark red, orange, or pink. As kidney cancer progresses, it may produce other symptoms such as persistent pain, pressure just below the ribs, or intense fatigue.

How long should I take the Axzyb Tablet?

The duration of treatment varies from person to person. Your doctor will decide treatment duration based on your condition, response to treatment, and tolerance to side effects. Your doctor may decrease your dose or stop your treatment temporarily or permanently if you experience side effects.

When should I call my doctor right away?

Get medical help right away if you have signs of allergic reaction such as rash, hives, itching, and blisters. Also, let your doctor know if you notice bleeding or blood in your cough, very high blood pressure, signs of thyroid problems such as a change in weight, nervousness, restlessness, weakness, thinning of hair after taking Axzyb Tablet. Also, if you feel sudden mood changes, fast heart rate, change in voice, fever, or chills, visit your doctor without delay.

What lab tests are important before starting Axzyb Tablet?

Your doctor may advise you to undergo lab or medical tests such as blood pressure, thyroid function, kidney function, liver or pancreatic function tests, complete blood counts, urine tests, blood mineral levels including sodium or potassium before starting this medication. Women of childbearing age should have a pregnancy test before starting this medicine.

Who should not take the Axzyb Tablet?

People who are allergic to axitinib or any other ingredient of this medicine should not take Axzyb Tablet. Talk to your doctor if you are not sure.

Does Axzyb Tablet affect fertility?

Yes, this medicine may cause fertility issues in males as well as females. Talk to your doctor before starting your treatment to know about ways to preserve fertility.

I feel exhausted after starting treatment with Axzyb Tablet. What should I do?

General tiredness/fatigue is a common side effect experienced during treatment with Axzyb Tablet. You may need to adjust your schedule to manage fatigue. Take ample amounts of rest and do not indulge in physically exhausting activities. Exercise, such as walking, can help cope up with fatigue.

How do I know if I have developed thyroid problems after taking Axzyb Tablet?

Regular monitoring of thyroid function is recommended before as well as during your treatment with Axzyb Tablet. Your doctor will advise blood tests to assess the same. Tell your doctor if you have symptoms such as feeling more tired than usual, weight gain or loss, sensitivity to hot or cold weather, hair loss, voice changes (such as deepening of the voice), muscle cramps, and aches.

What is Reversible Posterior Leukoencephalopathy Syndrome?

Reversible Posterior Leukoencephalopathy Syndrome (RPLS) is a rare but serious neurological complication associated with the use of Axzyb Tablet. It is characterized by symptoms such as headaches, vision problems, mental changes, seizures, high blood pressure, weakness, and swelling in the brain. This condition is reversible and symptoms subsides once treated. Consult your doctor right away if you experience any of these worrisome episodes while taking Inlyta tablets.

I have swelling in my ankles and feet after I started taking Axzyb Tablets? What does this mean?

This medicine may cause side effects such as excessive tiredness, swelling of the abdomen, legs, or ankles, shortness of breath, or protruding neck veins. These are alarming and indicate chances of developing heart failure. The use of Axzyb Tablet is associated with an increased risk of heart failure events and these symptoms must therefore be taken seriously and addressed at the earliest. Tell your doctor without any delay if you notice any of these episodes.

How can I store Axzyb Tablet at home?

Store the medicine at room temperature at a dry place beyond the reach of the children and pets to avoid any accidental intake.

Fact Box

Chemical Class

Diarylthioethers

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Tyrosine Kinase Inhibitors (TKIs)

Related lab tests

Complete Blood Count

References

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 111-12.
Axitinib. Sandwich, Kent: Pfizer Limited; 2012 [revised Nov. 2018]. [Accessed 26 Mar. 2019] (online) Available from:
Axitinib. New York, New York: Pfizer Inc.; 2012 [revised Aug. 2014]. [Accessed 26 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Glenmark Pharmaceuticals Ltd
Address: Glenmark Pharmaceuticals Limited, B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai – 400 026.

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Provide right medicines

Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose

In accordance with the law

Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945

Axzyb Tablet

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Axzyb Tablet

Benefits of Axzyb Tablet

Side effects of Axzyb Tablet

How to use Axzyb Tablet

How Axzyb Tablet works

All substitutes for Axzyb Tablet

Axpero 5 Tablet

Inlyta 5mg Tablet

Inlyta 5mg Tablet

Inlyta 5mg Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Acenocoumarol (Oral Route)

Phenindione (Oral Route)

Warfarin (Oral Route)

Atazanavir (Oral Route)

Bosentan (Oral Route)

Frequently asked questions

What are the possible signs and symptoms of kidney cancer?

How long should I take the Axzyb Tablet?

When should I call my doctor right away?

What lab tests are important before starting Axzyb Tablet?

Who should not take the Axzyb Tablet?

Does Axzyb Tablet affect fertility?

I feel exhausted after starting treatment with Axzyb Tablet. What should I do?

How do I know if I have developed thyroid problems after taking Axzyb Tablet?

What is Reversible Posterior Leukoencephalopathy Syndrome?

I have swelling in my ankles and feet after I started taking Axzyb Tablets? What does this mean?

How can I store Axzyb Tablet at home?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Complete Blood Count

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests