Aravon Injection

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Introduction

Aravon Injection is used in the treatment of amyotrophic lateral sclerosis (a nervous system disease that weakens the muscles and impairs physical functions). It is an antioxidant that slows down nerve damage and prevents further progression of the disease.

Aravon Injection is administered as an injection under the supervision of a healthcare professional and should not be self-administered. It is given in cases where oral administration is not possible. Take this medicine in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember.

The most common side effects of this medicine are headache, bruising, and walking difficulties (gait disturbance).  You may also notice some injection site reactions such as pain, redness, or swelling. However, these are temporary and usually resolve on their own. Please consult your doctor if these do not subside or bother you. You should inform the doctor if you develop any allergic reactions like itching, swelling of the lips, tongue, or face, after taking the medication as these require immediate medical attention.

Uses of Aravon Injection

Benefits of Aravon Injection

In Amyotrophic lateral sclerosis (ALS)

Amyotrophic lateral sclerosis (ALS) is a disease of the nerves that restricts muscle movements and hence affects the physical functions of the affected person. Aravon Injection improves nerve activity and muscle strength. This helps the person to carry out the daily activities like walking, talking, chewing, etc, more conveniently. Hence, the person becomes more confident.

Side effects of Aravon Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Aravon

  • Bruise
  • Walking difficulties
  • Headache
  • Injection site reactions (pain, swelling, redness)

How to use Aravon Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Aravon Injection works

Aravon Injection is an antioxidant. It has nootropic (enrichment of nerves) and neuroprotective properties. It works by slowing the nerve damage caused by harmful chemicals (free radicals). This delays the progression of amyotrophic lateral sclerosis (ALS) symptoms by reducing the oxidative stress (an imbalance between free radicals and antioxidants) in the brain.

Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Aravon Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Aravon Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Aravon Injection during breastfeeding is not available. Please consult your doctor.
Driving
CONSULT YOUR DOCTOR
It is not known whether Aravon Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Aravon Injection in patients with kidney disease. Please consult your doctor.
Liver
CAUTION
Aravon Injection should be used with caution in patients with severe liver disease. Dose adjustment of Aravon Injection may be needed. Please consult your doctor.
Limited information is available on the use of Aravon Injection in these patients. No dose adjustment is recommended in patients with mild to moderate liver disease.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Aravon Injection
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Quick tips

  • Aravon Injection slows decline of physical function and helps relieve symptoms of amyotrophic lateral sclerosis (ALS) such as muscle cramps and fatigue.
  • It is given through a needle into a vein by your healthcare provider.
  • It takes about 60 minutes to receive a full dose of Aravon Injection.
  • Wear relaxed, loose-fitting clothing and keep yourself hydrated when treated with this medicine.
  • Inform your doctor if you are pregnant or breastfeeding.
  • Inform your doctor immediately  if you experience itching, swelling of the lips, tongue, or face, breathing problems or have trouble swallowing after receiving this medicine.
  • Inform your doctor if you have a known allergy to sulfa drugs.

Fact Box

Chemical Class
Pyrazolones Derivative
Habit Forming
No
Therapeutic Class
NEURO CNS
Action Class
Nootropic agent

Patient concerns

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FAQs

Q. What are the side effects of Aravon Injection?

The most common side effects of Aravon Injection include confusion, headache, and difficulty in walking. Other uncommon side effects are skin allergy (rash and itching), breathing difficulty, chest tightness, wheezing, coughing (especially in people with asthma), and fungal infections.

Q. How is Aravon Injection given?

Aravon Injection injection comes as a solution (liquid) to be injected intravenously (into a vein) over 60 minutes by a health care professional in a doctor's office or medical facility. During the initial stage of treatment, Aravon Injection is usually given once a day for the first 14 days of a 28-day cycle. After the first cycle, it is given once a day for the first 10 days of a 28-day cycle. Your doctor will decide how often you are to receive Aravon Injection based on your body's response to this medication.

Q. Can amyotrophic lateral sclerosis (ALS) be cured by Aravon Injection?

Aravon Injection injection is used to treat amyotrophic lateral sclerosis (ALS). ALS is a condition in which the nerves that control muscle movement slowly die, causing the muscles to shrink and weaken. Aravon Injection works by slowing the nerve damage associated with the worsening of ALS symptoms.

Q. What should I tell my doctor before taking Edaravone?

Inform your doctor or pharmacist if you are allergic to edaravone, any other medications, sodium bisulfite, or any of the ingredients in Aravon Injection injection. If you are taking or planning to take any other prescription and nonprescription medications, vitamins, and nutritional supplements inform your doctor beforehand. Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Tell your doctor if you have or have ever had asthma or if you are pregnant or planning to conceive, or are breastfeeding. If you become pregnant while receiving edaravone, call your doctor.

Q. Can ALS be prevented?

There are no studies to support if ALS can be prevented or not. However, one can reduce the possibility of acquiring the disease by knowing various risk factors. The risk factors associated with ALS include smoking and exposure to pesticides and insecticides. In addition to that, another report suggests that people who have served in the military can also have high risks of developing ALS.

Q. Who is more likely to get affected by ALS? Is it age or gender specific?

Caucasians and non-Hispanics are most likely to develop the disease. About 5 to 10 percent of all ALS cases are familial, which means that an individual inherits the disease from his or her parents. ALS can strike at any age, symptoms most commonly develop between the ages of 55 and 75. It is slightly more likely to develop in men than in women. However, as we age the difference between men and women disappears. Furthermore, some studies suggest that military veterans are about 1.5 to 2 times more likely to develop ALS because of toxin exposure during warfare.

Q. Why so many veterans and athletes get ALS?

Researchers have suggested that exposure to toxins during warfare, or strenuous physical activity, are possible reasons for why some veterans and athletes may be at increased risk of developing ALS.

Q. What are the early symptoms of ALS?

The early symptoms of ALS include muscle twitches in the arm, leg, shoulder, or tongue, muscle cramps, tight and stiff muscles (spasticity), muscle weakness affecting an arm, a leg, neck or diaphragm, slurred and nasal speech and difficulty in chewing or swallowing. For many individuals the first sign of ALS may appear in the hand or arm as they experience difficulty with simple tasks such as buttoning a shirt, writing, or turning a key in a lock. In other cases, symptoms initially affect one of the legs, and people experience awkwardness when walking or running or they notice that they are tripping or stumbling more often.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Radicava. Edaravone. [Accessed 24 Jan. 2019] (online) Available from:External Link
  2. Edaravone injection. Jersey City, New Jersey: MT Pharma America, Inc.; 2017 [revised May 2017]. [Accessed 22 Mar. 2019] (online) Available from:External Link
  3. Central Drugs Standard Control Organisation (CDSCO). [Accessed 22 Mar. 2019] (online) Available from:External Link

Manufacturer/Marketer address

90, Delhi - Jaipur Road, Sector 32, Gurugram, Haryana 122001
Country of origin: India

Expires on or after: June, 2024

A licensed vendor partner from your nearest location will deliver Aravon Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
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