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Ampi Syrup

Written By Dr. Subita Alagh, BDS
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS
Last updated on 22 Jan 2026 | 11:00 AM (IST)
Ampi Syrup is an antibiotic medicine with versatile actions. It can treat a multitude of bacterial infections including those of the ears, eyes, nose, tonsils, tooth, throat, lungs, skin, bone, heart, gastrointestinal tract, and urinary tract. It may also be prescribed to treat typhoid fever in children.
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General Information

The content is shown in English
Ampi Syrup image
Ampi Syrup image

Your child’s medicine at a glance

Ampi Syrup works best on an empty stomach, so try to give it to your child ½ - 1 hour before they eat. However, give it with food if it upsets your child’s stomach. It is generally given three times a day. Stick to the dose, time, and way prescribed by the doctor as these depend on the severity of the infection, its type, and your child’s body weight and age. If your child vomits within 30 minutes of taking the medicine, repeat the dose when your child feels better. However, do not double the dose if it is the time for the next dose.

Ampi Syrup can cause some minor and temporary side effects such as nausea, vomiting, diarrhea, abdominal pain, and mild skin rash. These side effects should ideally subside on their own. But, in case these side effects persist or become bothersome for your child, report to the doctor without a delay.

Tell your child’s doctor if your child has had any previous episode of allergy, heart problem, blood disorder, birth defects, airway obstruction, lung anomaly, gastrointestinal problem, skin disorder, and kidney malfunction. Knowledge of your child’s medical history will help the dose make dose alterations and plan your child’s overall treatment.

Uses of Ampi Syrup in children

Benefits of Ampi Syrup for your child

Treatment of Typhoid fever
Typhoid fever is an infection of the gastrointestinal tract that spreads through contaminated food and water. Symptoms of such infection include high fever, headache, stomach pain, weakness, vomiting, and loose stools. Ampi Syrup is given to eradicate Salmonella typhi bacteria which is responsible for causing typhoid in children. Keep giving Ampi Syrup to your child as prescribed for it to be effective, even if the symptoms seem to disappear.

Side effects of Ampi Syrup in children

Ampi Syrup does not pose serious side effects and is well-tolerated by children. In case the side effects do occur, they’re likely to subside once the body adapts to the medicine. Consult your child’s doctor if these side effects persist or bother your child. The most common side effects include-
Common side effects of Ampi
  • Abdominal pain
  • Headache
  • Allergy

How can I give Ampi Syrup to my child?

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Ampi Syrup is to be taken on an empty stomach.

How Ampi Syrup works

Ampi Syrup is an antibiotic. It works by preventing the formation of the bacterial protective covering (cell wall) which is essential for the survival of the bacteria. By doing so, this medicine kills the infection-causing bacteria and prevents the infection from spreading without making them resistant to further treatment.

Quick tips

  • Complete the entire course of antibiotics without stopping the medicine in between. Doing so may cause the bacteria to multiply again, become resistant, or cause another infection.
  • Make sure your child drinks plenty of water if they develop diarrhea as a side effect.
  • Conditions like common cold and flu are caused by viruses. Never use this medicine for such conditions.
  • Give Ampi Syrup to your child only for their current infection. Avoid storing the medicine for future use as it is impossible to judge whether the same medicine would work for any future illnesses.
  • Stop this medicine and immediately report to your child’s doctor in case your child develops an itchy rash, facial swelling, or breathing difficulties while taking this medicine.
  • Ampi Syrup is used to treat infections caused by bacteria.
  • Finish the prescribed course, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.
  • Diarrhea may occur as a side effect. Taking probiotics along with Ampi Syrup may help. Talk to your doctor if you notice bloody stools or develop abdominal cramps.
  • Take it with food and plenty of fluids to avoid an upset stomach.
  • Stop taking this medicine and inform your doctor immediately if you develop an itchy rash, swelling of the face, throat or tongue or breathing difficulties while taking it.

Safety advice

Kidney

Kidney

CAUTION
Ampi Syrup should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Liver

Liver

SAFE IF PRESCRIBED
Ampi Syrup is probably safe to use in patients with liver disease. Limited data suggest dose adjustment may not be needed.

Interaction with drugs

Taking Ampi with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Cholera Vaccine (Inactivated) (Oral Route)

Do not consume Cholera Vaccine (Inactivated) two weeks before and at least 10 days after consuming Ampicillin. Please consult your doctor. Ampicillin may reduce the efficacy of Cholera Vaccine (Inactivated).
Severe

Purified Vi Polysaccharide Typhoid Vaccine (Injection Route)

Ampicillin may reduce the efficacy of Purified Vi Polysaccharide Typhoid Vaccine. Ampicillin may reduce the efficacy of Purified Vi Polysaccharide Typhoid Vaccine.
Moderate

Pemetrexed (Injection Route)

Your doctor may monitor your creatinine clearance along with your overall treatment and adjust the doses as per the observations. Ampicillin may slow down the removal of Pemetrexed from the body.
Moderate

Methotrexate (Oral Route)

Please consult with your doctor. Doctor may monitor liver function and blood cell counts. Ampicillin may reduce the efficacy of Methotrexate.
Moderate

Acenocoumarol (Oral Route)

Your doctor may monitor the blood's clotting ability within 3 days of starting or discontinuing Ampicillin.

Frequently asked questions

Giving your child Ampi Syrup for a long term can cause fungal infection (oral thrush) in the mouth and severe gastrointestinal infections (superinfections). Therefore, do not alter the dose and duration on your own and give Ampi Syrup to your child exactly as prescribed. Additionally, irregular treatment, repeated use, and misuse of Ampi Syrup can make the bacteria resistant.
Although rare, Ampi Syrup may cause some serious side effects such as skin rash, allergy, superinfection, bleeding problems, seizures, and blood cell abnormalities. If your child experiences any such symptoms, consult the doctor at the earliest.
Ampi Syrup can sometimes interact with other medicines or substances. Tell your doctor about any other medicines your child is taking before starting Ampi Syrup. Also, check with your child’s doctor before giving any medicine to your child.
Antibiotics usually do not interfere with the ingredients in vaccines or cause a bad reaction in a child who has just been vaccinated. However, children taking antibiotics should not get vaccinated until they recover from the illness. As soon as your child feels better, the vaccine can be given.
In the common cold, the mucus changes its color and thickens up with time, but this does not mean that your child needs antibiotics. Common cold symptoms often last for 7-10 days. In case they fail to clear up within this duration, reach out to your child’s doctor for guidance.
No, do not give this medicine to your child in this case as a high percentage of children with infectious mononucleosis develop a skin rash (erythematous rash) while taking Ampi Syrup.

Fact Box

Chemical Class

Penicillins

Habit Forming

No

Therapeutic Class

ANTI INFECTIVES

Action Class

Extended Spectrum Penicillins

References

  1. Petri WA Jr. Penicillins, Cephalosporins, and Other β -Lactam Antibiotics. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1487-90.
  2. Chambers HF, Deck DH. Beta-Lactam and Other Cell Wall- & Membrane-Active Antibiotics. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 780.
  3. University of Michigan: C.S. Mott Children’s Hospital. Ampicillin. [Updated 02 Feb. 2019]. [Accessed 16 Feb. 2021] (online) Available from:
  4. Pediatric Trials Network. The Ampicillin in Infants Study. [Accessed 16 Feb. 2021] (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Shalina Laboratories Pvt Ltd
Address: C/48/3, TTC Industrial Area, Pawane, Navi Mumbai - 400703

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Country of origin: India
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