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Amotic Tablet

Written By Dr. Swati Mishra, BDS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 31 Mar 2026 | 02:31 PM (IST)
Amotic Tablet is a medicine used to control nausea and vomiting due to certain medical conditions like stomach upset. It is also used to prevent nausea and vomiting caused due to surgery, cancer drug therapy, or radiotherapy.
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₹41.5 MRP ₹45.9410% off 
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General Information

Contains

Ondansetron (4mg)

Marketer

Signature Phytochemical Industries

Storage

Store below 30°C
The content is shown in English
Amotic Tablet image
Amotic Tablet image

Product introduction

Amotic Tablet may be used alone or with other medications and can be taken with or without food. Your doctor will suggest the appropriate dose depending on what you are taking it for. The first dose is normally taken before the start of surgery, chemotherapy, or radiotherapy. After these treatments, take any further doses as prescribed by your doctor (normally only for a few days at most). Take it regularly at the same time(s) each day to get the most benefit. Be careful not to take too much.


Amotic Tablet does not relieve other side effects associated with cancer treatments. Also, it has little effect on vomiting caused by motion sickness. The most common side effects of taking this medicine include headache, diarrhea or constipation, and feeling tired. These symptoms should disappear when you stop taking the medicine. However, if these side effects bother you or do not go away, your doctor may be able to suggest ways of preventing or reducing them.


Before taking Amotic Tablet, tell your doctor if you have heart or liver problems or a blockage in your stomach or intestines. Also, tell your doctor about any other medicines you might be taking, especially medicines to treat epilepsy, heart problems, cancer, and depression. These may affect, or be affected by, this medicine. If you are pregnant or breastfeeding, ask for advice from your doctor.

Uses of Amotic Tablet

Benefits of Amotic Tablet

Treatment and prevention of Vomiting
Amotic Tablet is used to prevent and treat vomiting by blocking signals in the brain that trigger the vomiting reflex. It provides quick relief and helps patients feel more comfortable, especially after surgery, chemotherapy, or certain illnesses.
Treatment and prevention of Nausea
Amotic Tablet helps relieve nausea by blocking chemical signals in the brain that cause the feeling of sickness. It is especially useful for nausea related to chemotherapy, radiation therapy, or surgery, making patients feel more at ease.

Side effects of Amotic Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Amotic
  • Fatigue
  • Headache
  • Constipation
  • Diarrhea

How to use Amotic Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Amotic Tablet may be taken with or without food.

How Amotic Tablet works

Amotic Tablet is an antiemetic medication. It works by blocking the action of a chemical messenger (serotonin) in the brain that may cause nausea and vomiting during anti-cancer treatment (chemotherapy) or after surgery.

All substitutes for Amotic Tablet

For information purposes only. Consult a doctor before taking any medicine.

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Emeset 4 ODT Tablet

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Quick tips

  • You have been prescribed Amotic Tablet for the prevention of nausea and vomiting caused by surgery or due to chemotherapy and radiotherapy.
  • It is fast-acting and starts working within 30 minutes.
  • If you vomit within one hour of taking a dose, take another dose.
  • Avoid heavy meals and try eating small, nourishing snacks throughout the day. Also, sip water regularly to help avoid dehydration.

Safety advice

Alcohol

Alcohol

SAFE
Consuming alcohol with Amotic Tablet does not usually cause any harmful side effects.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Amotic Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

CAUTION
Amotic Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.
Driving

Driving

SAFE
Amotic Tablet does not usually affect your ability to drive.
Kidney

Kidney

CAUTION
Amotic Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
However, inform your doctor if you have an underlying kidney disease. Limited information is available in patients taking this medicine for more than one day.
Liver

Liver

CAUTION
Amotic Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Amotic with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Life-threatening

Disopyramide (Oral Route)

Do not consume Ondansetron with Disopyramide.
Life-threatening

Amiodarone (Oral Route)

Do not consume Ondansetron with Amiodarone.
Life-threatening

Amiodarone (Injection Route)

Do not consume Ondansetron with Amiodarone.
Life-threatening

Amisulpride (Oral Route)

Do not consume Ondansetron with Amisulpride.
Life-threatening

Amisulpride (Injection Route)

Do not consume Ondansetron with Amisulpride.

Frequently asked questions

Amotic Tablet starts working within half an hour to 2 hours. It dissolves rapidly into the bloodstream and starts showing its effect.
The most common side effects of Amotic Tablet are constipation, diarrhea, fatigue, and headache. However, these are usually not bothersome and resolve on their own after some time. Consult your doctor if these persist or worry you.
Amotic Tablet should be taken with a full glass of water, with or without food. It should be used exactly as per the dose and duration advised by the doctor. Usually, the first dose of Amotic Tablet is taken before the start of your surgery, chemotherapy, or radiation treatment.
No, Amotic Tablet is an antiemetic and not a steroid. Amotic Tablet is a selective 5-HT3 receptor antagonist. It is prescribed for the prevention and treatment of nausea and vomiting, which is commonly observed after surgery or due to cancer chemotherapy.
No, Amotic Tablet does not work for seasickness. This is because Amotic Tablet has very little effect on the nausea associated with motion sickness.

Fact Box

Chemical Class

Carbazoles

Habit Forming

No

Therapeutic Class

GASTRO INTESTINAL

Action Class

Serotonin 5-HT3 Receptor Antagonists

References

  1. Sharkey KA, Wallace JL. Treatment of Disorders of Bowel Motility and Water Flux; Anti-Emetics; Agents Used in Biliary and Pancreatic Disease. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1341-42.
  2. Katzung BG. Histamine, Serotonin, & the Ergot Alkaloids. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 285
  3. Ondansetron. Portage, IN: Monosol Rx, LLC; 1991 [revised Jul. 2010]. [Accessed 28 Mar. 2019] (online) Available from:
  4. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Ondansetron. [Updated 2019 Feb 7]. [Accessed 20 Feb. 2020] (online) Available from:
  5. Central Drugs Standard Control Organisation (CDSCO). [Accessed 28 Mar. 2019] (online) Available from:
  6. Ondansetron hydrochloride [Prescribing Information]. Research Triangle Park, NC: GlaxoSmithKline; 2016. [Accessed 25 Jul. 2024] (online) Available from:
  7. Ondansetron [Prescribing Information]. Mahwah, NJ: Glenmark Pharmaceuticals Inc.; 2021. [Accessed 19 Mar. 2025] (online) Available from:
  8. Ondansetron [Prescribing Information]. 2022. [Accessed 19 Mar. 2025] (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Signature Phytochemical Industries
Address: 122 MI, Selaqui Industrial Area,Dehradun,Uttarakhand - 248197

Vendor Details

Country of origin: India

Lab tests offered by us

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