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MDS (Oral Pathology & Microbiology), BDS
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Last updated on:
14 Jun 2019 | 12:34 PM (IST)
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Amlodepin 5 mg Tablet


Overview

Introduction of Amlodepin Tablet

Amlodepin 5 mg Tablet is a medicine used to treat hypertension (high blood pressure) and angina (heart-related chest pain). It helps to lower high blood pressure, thus reducing the chances of future heart attack and stroke. This medicine should be used along with a proper diet, salt restriction, and regular exercise for best results. It should be taken regularly at a fixed time every day. This medicine should not be stopped abruptly. You may experience mild dizziness initially while taking this medicine, which improves with time. Swelling of the ankle may occur in some patients as a side effect.

Uses of Amlodepin Tablet

Amlodepin Tablet side effects

Common
  • Fatigue
  • Ankle swelling
  • Sleepiness
  • Flushing (sense of warmth in the face, ears, neck and trunk)
  • Headache
  • Nausea
  • Dizziness
  • Palpitations
  • Edema (swelling)
  • Abdominal pain

How to use Amlodepin Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Amlodepin 5 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Amlodepin Tablet works

Amlodepin 5 mg Tablet is a calcium channel blocker. It works by relaxing blood vessels which makes the heart more efficient at pumping blood throughout the body.

Amlodepin Tablet related warnings

Alcohol
CAUTION
It is unsafe to consume alcohol with Amlodepin 5 mg Tablet.
Pregnancy
WEIGH RISKS VS BENEFITS
Amlodepin 5 mg Tablet may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the fetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Lactation
Amlodepin 5 mg Tablet is probably safe to use during lactation. Limited human data suggests that the drug does not represent a significant risk to the baby.
Driving
Do not drive unless you are feeling well.
Amlodepin 5 mg Tablet may cause side effects such as dizziness, headaches, nausea or tiredness, all of which could affect your ability to concentrate and drive.
Kidney
SAFE
Amlodepin 5 mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Amlodepin 5 mg Tablet is recommended.
Liver
CAUTION
Amlodepin 5 mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Amlodepin 5 mg Tablet may be needed. Please consult your doctor.
Amlodepin 5 mg Tablet is started at a lower dose in patients with liver disease and further increased slowly with careful monitoring.

What if you miss a dose of Amlodepin Tablet?

If you miss a dose of Amlodepin 5 mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Amlodepin 5 mg Tablet
₹0.49/Tablet
Amlong Tablet
Micro Labs Ltd
₹2.74/Tablet
465% costlier
Amlokind 5 Tablet
Mankind Pharma Ltd
₹1.25/Tablet
157% costlier
Amlovas 5 Tablet
Macleods Pharmaceuticals Pvt Ltd
₹2.75/Tablet
465% costlier
₹2.86/Tablet
488% costlier
₹2.59/Tablet
433% costlier

Expert Advice

  • A sudden drop in your blood pressure may occur, especially when you first start taking Amlodepin 5 mg Tablet. To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
  • It can cause ankle or foot swelling. Raise your legs while you are sitting down. Talk to your doctor if it does not go away.
  • It may cause dizziness. Do not drive or perform activity require mental focus until you know how $affects you. 
  • Inform your doctor if you are pregnant, planning pregnancy or breastfeeding. 

Interaction with Drugs

Taking Amlodepin with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Stoin
SERIOUS
Brand(s): Zuroxy, Roxilim, Rox Thro
SERIOUS
Brand(s): Ranisol, Vepred
SERIOUS
Brand(s): Shinosun
SERIOUS
Brand(s): Indizole, Itracip, Itraspan
SERIOUS
Brand(s): Rosidoc, Rosustin, Rosucad
SERIOUS

Patient Concerns

Questions Related to Amlodepin

arrow
Blood pressure is high which medicine to give it is 164/92
Dr. Vikas Sharma
Neurologist
Amlodepin 5 mg of
right side of pain in chest below the brest it will be a some painclear take give &short period relief please suggestions me they permant advice it will be a Blood pressure problem it will be a taking amlodepin&Telmistarn tablet
Dr. Nabajit Talukdar
Heart Specialist
need to see u .u can see me at medanta opd call 9XXXXXX
arrow
Do you have any questions related to Amlodepin 5 mg Tablet?

User Feedback


FAQs

Q. What is Amlodepin used for?

Amlodepin is indicated for the treatment of high blood pressure (hypertension), angina pectoris (pain in the chest caused by blockages in the arteries leading to the heart) or chest pain classed as vasospastic angina pectoris (or Prinzmetal’s angina).

Q. Is Amlodepin a calcium channel blocker and how does it works?

Amlodepin is a calcium channel blocker. In patients with high blood pressure, it works by relaxing blood vessels, so that blood passes through them more easily. In patients with angina, it works by improving blood supply to the heart muscle, which then receives more oxygen, and hence, prevents chest pain. It does not provide immediate relief of chest pain from angina.

Q. Is Amlodepin safe?

Amlodepin is safe if used at prescribed doses for the prescribed duration as advised by your doctor.

Q. Can I take Amlodepin at night?

Amlodepin can be taken at night. You should take Amlodepin at the same time each day with a glass of water.

Q. Can I take Amlodepin and aspirin?

Amlodepin can be taken with aspirin. No drug-drug interactions have been reported between the two. However, interactions can occur. Please consult your doctor before taking the two medicines together.

Q. Can I take Amlodepin with sildenafil?

Both Amlodepin and sildenafil cause a lowering the blood pressure. So, taking the two medicines together could be harmful. Please consult your doctor before taking them together.

Q. Is Amlodepin safe for kidneys?

Amlodepin is not known to damage kidneys. However, Amlodepin can cause urinary disorders like difficulty in passing urine, increased the need to urinate at night, increased number of times of passing urine as an uncommon side effect.

Q. Does Amlodepin cause tachycardia?

Amlodepin can rarely cause changes in heart rate, which can be an increase (tachycardia) or a decrease in heart rate (bradycardia) or an irregular heart rate. Please consult your doctor if you experience any changes in your heart rate while taking Amlodepin.

Q. Does Amlodepin cause pedal edema (swelling of the ankles)?

Amlodepin can cause pedal edema (swelling of the ankles). Please consult your doctor if you have pedal edema while taking Amlodepin.

Q. Does Amlodepin increase creatinine?

Amlodepin has not been reported to increase creatinine levels. Please consult your doctor if you have increased creatinine levels while taking Amlodepin as it requires proper diagnosis and management.

Q. Does Amlodepin cause erectile dysfunction?

Erectile dysfunction is an uncommon side effect of Amlodepin. Please consult your doctor if you experience erectile dysfunction when you are taking Amlodepin.

Q. Does Amlodepin cause weight gain?

Amlodepin can cause changes in weight, it can either cause weight gain or weight loss. However, these changes are very rare. Please consult your doctor if you experience a change in weight while taking Amlodepin.

Q. Does Amlodepin cause joint pain (arthralgia)?

Amlodepin can cause joint pain (arthralgia). Please consult your doctor if you experience excessive joint pains while taking Amlodepin.

Q. Does Amlodepin cause cough?

Amlodepin can cause cough, but it is a very rare side effect. Please consult your doctor if you experience excessive coughing while taking Amlodepin.

Q. Does Amlodepin cause dry mouth?

Amlodepin can cause dry mouth as an uncommon side effect. Please consult your doctor if you experience excessive dryness of mouth after taking Amlodepin.

Q. Can I take Amlodepin without food?

Amlodepin can be taken before or after food and drinks. Amlodepin should be taken same time each day with a glass of water. Do not take Amlodepin with grapefruit juice.

Q. Can I take Amlodepin with ramipril?

Amlodepin and ramipril both have a blood pressure lowering effect. So, taking both the medicines together can be harmful. Please consult your doctor before taking the two medicines together.

Q. Can I take Amlodepin with simvastatin?

Amlodepin can increase the levels of simvastatin, causing an increased tendency towards myopathy (muscle pain) and rhabdomyolysis (increased breakdown of muscle). The dose of simvastatin may need to be reduced when giving along with Amlodepin . Please consult your doctor.

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Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Michel T, Hoffman BB. Treatment of Myocardial Ischemia and Hypertension. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 758-60.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 60-61.
  3. Opie LH. Calcium Channel Blockers. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. pp. 86-88.
  4. Amlodipine besylate. New York, New York: Pfizer; 2011. [Accessed 23 Jan. 2019] (online) Available from:External Link
  5. Amlodipine besylate. new York, New York: Pfizer Labs.; 1987 [revised May 2011]. [Accessed 14 Mar. 2019] (online) Available from:External Link
  6. Drugs.com. Amlodipine Pregnancy and Breastfeeding Warnings. [Accessed 14 Mar. 2019] (online) Available from:External Link
  7. U.S. National Library of Medicine. Amlodipine. [revised 03 Dec. 2018]. [Accessed 14 Mar. 2019] (online) Available from:External Link
  8. Central Drugs Standard Control Organisation (CDSCO). Amlodipine. [Accessed 14 Mar. 2019] (online) Available from:External Link
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