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Last updated on:
15 Jul 2019 | 01:01 PM (IST)
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Alphadex 100 mcg Injection


Overview

Uses of Alphadex Injection

Alphadex Injection side effects

Common
  • Dryness in mouth
  • Decreased blood pressure
  • Slow heart rate

How to use Alphadex Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Alphadex Injection works

Alphadex 100 mcg Injection works by modulating the action of certain chemical messengers in the brain that relieves pain and induces sleep.

Alphadex Injection related warnings

Alcohol
CAUTION
Alphadex 100 mcg Injection may cause excessive drowsiness and calmness with alcohol.
Pregnancy
WEIGH RISKS VS BENEFITS
Alphadex 100 mcg Injection may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the fetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Lactation
Alphadex 100 mcg Injection is probably safe to use during lactation. Limited human data suggests that the drug does not represent a significant risk to the baby.
Driving
Not relevant, as Alphadex 100 mcg Injection is intended for use in hospitalised patients.
Kidney
SAFE
Alphadex 100 mcg Injection is safe to use in patients with kidney disease. No dose adjustment of Alphadex 100 mcg Injection is recommended.
Liver
CAUTION
Alphadex 100 mcg Injection should be used with caution in patients with liver disease. Dose adjustment of Alphadex 100 mcg Injection may be needed. Please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Alphadex 100 mcg Injection
Dextomid 100mcg Injection
Neon Laboratories Ltd
₹390/ml of Injection
30% costlier
Dexem 100mcg Injection
Themis Medicare Ltd
₹345/ml of Injection
15% costlier
₹232/ml of Injection
save 23%
Dexmedine Injection
Samarth Life Sciences Pvt Ltd
₹200/ml of Injection
save 33%
Dexem 100mcg Injection
Themis Medicare Ltd
₹423.5/ml of Injection
41% costlier

Expert Advice

  • You may be monitored for change in heart rate and blood pressure during treatment with dexmedetomidine.
  • Dexmedetomidine should not be infused for periods >24 hours. It is not necessary to discontinue the drug prior to extubation (removal of tube placed in windpipe) provided that duration of infusion is ?24 hours.
  • Continuous cardiac and respiratory monitoring is recommended in patients receiving dexmedetomidine infusion.
  • Use with caution if you have abnormally slow heart rate, low blood pressure, low blood volume (e.g. after bleeding), certain heart disorders, neurological disorder (e.g. head or spinal cord injury or stroke), severe liver problems or have ever developed a serious fever after some medicines, especially anaesthetics.
  • Talk to your doctor if you are pregnant or planning to become pregnant. Do not breastfeed while on Dexmedetomidine.

FAQs

Q. What is Alphadex/Alphadex HCL used for?

Alphadex. Alphadex HCL is used to provide sedation (a state of calm, drowsiness or sleep) for adult patients in intensive care settings (i.e. in initially intubated and mechanically ventilated patients or non-intubated patients prior to and/or during surgical and other procedures)

Q. What class is Alphadex/ is Alphadex a controlled substance?

It is a sedative that belongs toclassof drugs called centrally active selective 2A agonists.It is not a controlled drug/substance

Q. Is Alphadex approved by FDA?

Yes, Alphadex approved by FDA

Q. Does Alphadex cause amnesia/pain on inje ction/bradycardia?

Alphadex is given as an infusion (drip) into veins. It may cause pain at injection site and low heart rate (bradycardia). It does not cause amnesia

Q. How does Alphadex work?

Alphadex activates the central 2A receptors which causes sedation and analgesia.

Related Products

Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Stahl SM, editor. Dextromethorphan. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 181-83.
  2. Patel PM, Patel HH, Roth DM. General Anesthetics and Therapeutic Gases. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 548-49.
  3. Biaggioni I, Robertson D. Adrenoreceptor Agonists & Sympathomimetic Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 140, 145.
  4. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 381-82.
  5. Dexmedetomidine hydrochloride. Lake Forest, Illinois: Hospira, Inc.; 1999 [revised Jun. 2013]. [Accessed 12 Feb. 2019] (online) Available from:External Link
  6. U.S. National Library of Medicine. Dexmedetomidine. [Accessed 22 Mar. 2019] (online) Available from:External Link
  7. Central Drugs Standard Control Organisation (CDSCO). [Accessed 22 Mar. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
Fusion House, Plot No. 22, H.No 8-2-350/B, Road No. 3, Banjara Hills, Hyderabad, Telangana-500034
A licensed pharmacy from your nearest location will deliver Alphadex 100mcg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your prescription and the availability of this medicine.
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