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Afdol Injection

Written By Dr. Swati Mishra, BDS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 19 Sep 2025 | 03:31 PM (IST)
Afdol Injection is a pain-relieving medicine. It is used to manage persistent, moderate to severe chronic pain that requires continuous, around-the-clock treatment.
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General Information

Contains

Tramadol (NA)

Marketer

Anglo-French Drugs & Industries Ltd

Storage

Store below 30°C
The content is shown in English
Afdol Injection image
Afdol Injection image

Product introduction

Afdol Injection is generally administered by a healthcare professional. You should not self-administer this medicine at home. The dose and duration will depend on what you are taking it for and how well it helps your symptoms.

The most common side effects of this medicine include nausea, constipation, dry mouth, sleepiness, dizziness, and vomiting. If any of these side effects persist or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms.

Before using it, you should let your doctor know if you have problems with your heart, liver, or kidneys. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine.

If you are pregnant or breastfeeding, it is important to ask the advice of your doctor before taking this medicine. Your doctor may also regularly monitor your kidney function, liver function, and levels of blood components if you are taking this medicine for long-term treatment.

Uses of Afdol Injection

  • Moderate to severe pain

Benefits of Afdol Injection

Moderate to severe pain
Afdol Injection helps to relieve moderate to severe pain in conditions that affect joints and muscles. It works by blocking chemical messengers in the brain that tell us we have pain. It can help relieve pain in conditions like rheumatoid arthritis and osteoarthritis.
It is given as an injection by a doctor or nurse and should not be self-administered. The dose and duration will be decided by the doctor depending on the condition you are being treated for. This will help you to go about your daily activities more easily and have a better, more active, quality of life.

Side effects of Afdol Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Afdol
  • Nausea
  • Constipation
  • Sleepiness
  • Dizziness
  • Vomiting

How to use Afdol Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Afdol Injection works

Afdol Injection is an opioid analgesic (pain reliever) which works by blocking transmission of pain signals to the brain to lower pain perception.

Quick tips

  • Use only for severe acute pain for not more than 5 days.
  • Prolonged use may result in physical and psychological dependence even at recommended dosages.
  • Avoid driving or using machinery if you feel dizzy after taking Afdol Injection.
  • It is better to take with food to avoid an upset stomach.
  • Your doctor may adjust your dose if you have liver or kidney disease.

Safety advice

Alcohol

Alcohol

UNSAFE
It is unsafe to consume alcohol with Afdol Injection.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Afdol Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding

Breast feeding

SAFE IF PRESCRIBED
Afdol Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Consult a doctor immediately if the baby shows signs of increased sleepiness (more than usual), difficulty breastfeeding, breathing problems, or limpness.
Driving

Driving

UNSAFE
Afdol Injection may cause side effects which could affect your ability to drive.
Afdol Injection may cause side effects such as drowsiness and blurred vision. If this happens, do not drive.
Kidney

Kidney

CAUTION
Afdol Injection should be used with caution in patients with kidney disease. Dose adjustment of Afdol Injection may be needed. Please consult your doctor.
Liver

Liver

CAUTION
Afdol Injection should be used with caution in patients with liver disease. Dose adjustment of Afdol Injection may be needed. Please consult your doctor.

Interaction with drugs

Taking Afdol with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Life-threatening

Selegiline (Oral Route)

Do not consume Selegiline with Tramadol. If essential, watch out for symptoms such as fever, tremors, diarrhea or agitation. Please consult your doctor.
Life-threatening

Naltrexone (Oral Route)

Do not consume Naltrexone with Tramadol; watch out for symptoms such as breathlessness, increased heart rate, or headache. Naltrexone may reduce efficacy of Tramadol.
Life-threatening

Tranylcypromine (Oral Route)

Do not consume Tranylcypromine with Tramadol. If Tranylcypromine is essential, ensure a gap of At least 2 weeks between taking Tranylcypromine and Tramadol. Please consult your doctor.
Severe

Alprazolam (Oral Route)

If concurrent use is essential, watch out for symptoms of Alprazolam side effects such as drowsiness, excessive sedation, tiredness, dizziness or slurred speech and consult your doctor if you experience them. They may adjust the dose of Alprazolam as per the observations. It is advised to avoid driving or undertaking other tasks requiring skill and alertness.
Severe

Alprazolam (Injection Route)

If concurrent use is essential, watch out for symptoms of Alprazolam side effects such as drowsiness, excessive sedation, tiredness, dizziness or slurred speech and consult your doctor if you experience them. They may adjust the dose of Alprazolam as per the observations. It is advised to avoid driving or undertaking other tasks requiring skill and alertness.

Frequently asked questions

Afdol Injection may cause drowsiness and dizziness, especially in the beginning of the treatment. Do not drive or work with tools or machinery if your alertness is affected. It is not advisable to drink alcohol during treatment with this medicine as it might increase sleepiness.

Fact Box

Chemical Class

Anisole Derivative

Habit Forming

Yes

Therapeutic Class

PAIN ANALGESICS

Action Class

Opioids

References

  1. Schumacher MA, Basbaum AI, Way WL. Opioids Analgesics & Antagonists. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 547.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1384-86.
  3. ScienceDirect. Tramadol. [Accessed 02 Apr. 2019] (online) Available from:
  4. Central Drugs Standard Control Organisation (CDSCO). [Accessed 02 Apr. 2019] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Anglo-French Drugs & Industries Ltd
Address: No. 41, 3rd Cross, 5th Block, Rajajinagar, Bengaluru – 560 010, Karnataka , India

Vendor Details

Country of origin: India

Lab tests offered by us

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Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945
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