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ACTAMIDE 250MG TABLET

Written By Dr. Sakshi Jain, MS, BDS
Reviewed By Dr. Mekhala Chandra, MD, MBBS
Last updated on 20 Jan 2026 | 11:47 AM (IST)
ACTAMIDE 250MG TABLET is a medicine used to reduce pressure in the eyes. This pressure can be caused by or lead to an illness called glaucoma. If the pressure in your eye is too high, it can damage your sight. ACTAMIDE 250MG TABLET works by decreasing the amount of fluid inside the eye.
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General Information

The content is shown in English
ACTAMIDE 250MG TABLET image
ACTAMIDE 250MG TABLET image

Product introduction

You can take ACTAMIDE 250MG TABLET with or without food. The dose will depend on your condition and how you respond to the medicine. Try to take it at the same time each day. It is important to keep taking this medicine until your doctor tells you not to. Use this medicine regularly to get the most benefit from it, even if you feel well.


The most common side effect is headache. Other side effects include feeling tired, dizziness, and a change in taste. Make sure you read the leaflet that comes with your medicines and tell your doctor if you are bothered by side effects or if they do not go away. It may be possible to adjust your dose or try a different medicine. It is also reported to cause choroidal effusion (fluid buildup between the choroid and sclera) or choroidal detachment (separation of the choroid from the sclera due to fluid accumulation) in some people. If you experience such reactions, inform your doctor.


Avoid using this medicine if you have a known history of allergic reaction to any of the components of this medicine. Let your doctor also know about all the medicines you are taking to make sure it is safe for you. Additionally, let your doctor know if you have kidney or liver disease, heart trouble, or diabetes before taking the medicine. Pregnant and breastfeeding women should consult their doctor before using this medicine, as it may cause harmful effects to the mother or the developing baby.

Uses of Actamide Tablet

Benefits of Actamide Tablet

Treatment of Glaucoma
Glaucoma is a condition where increased pressure in the eye (intraocular pressure) can damage the optic nerve, leading to vision loss if untreated. ACTAMIDE 250MG TABLET is used to help lower this pressure by reducing the production of fluid inside the eye. This helps protect the optic nerve, slows down disease progression, and preserves vision.

Side effects of Actamide Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Actamide
  • Headache
  • Dizziness
  • Tiredness
  • Taste change

How to use Actamide Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. ACTAMIDE 250MG TABLET may be taken with or without food.

How Actamide Tablet works

ACTAMIDE 250MG TABLET is a carbonic anhydrase inhibitor. It works in glaucoma by decreasing the production of aqueous humour (fluid in the eye), thereby lowering the increased eye pressure.

Quick tips

  • ACTAMIDE 250MG TABLET helps lower high pressure in the eye and reduces the risk of vision loss.
  • Usually used in combination with other anti-glaucoma medications.
  • Take it as per the dose and duration suggested by your doctor.
  • Use caution while driving or doing anything that requires concentration, as ACTAMIDE 250MG TABLET can make you very drowsy.
  • It may cause a tingling sensation in the hands and feet. Take potassium-rich foods (bananas and coconut water), and get potassium levels checked regularly.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with ACTAMIDE 250MG TABLET. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of ACTAMIDE 250MG TABLET during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

SAFE IF PRESCRIBED
ACTAMIDE 250MG TABLET may be safe to use during breastfeeding. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Driving

Driving

UNSAFE
ACTAMIDE 250MG TABLET may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
ACTAMIDE 250MG TABLET should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Liver

Liver

UNSAFE
ACTAMIDE 250MG TABLET is unsafe to use in patients with liver disease and should be avoided.

Interaction with drugs

Taking Actamide with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Phenobarbitone (Oral Route)

If concurrent use is essential, watch out for symptoms such as fatigue, muscle pain, joint pain, or numbness, and consult your doctor if you experience them. They may adjust the dose of Acetazolamide accordingly.
Severe

Phenytoin (Oral Route)

If concurrent use is essential, watch out for symptoms such as blurred vision, sedation, drowsiness, impaired coordination, or impairment of visual coordination, and consult your doctor if you experience them. Your doctor may monitor and adjust the doses as per the observations.
Severe

Phenytoin (Injection Route)

If concurrent use is essential, watch out for symptoms such as blurred vision, sedation, drowsiness, impaired coordination, or impairment of visual coordination, and consult your doctor if you experience them. Your doctor may monitor and adjust the doses as per the observations.
Severe

Phenobarbitone (Injection Route)

If concurrent use is essential, watch out for symptoms such as fatigue, muscle pain, joint pain, or numbness, and consult your doctor if you experience them. They may adjust the dose of Acetazolamide accordingly.
Severe

Primidone (Oral Route)

If concurrent use is essential, watch out for symptoms such as fatigue, muscle pain, joint pain, or numbness, and consult your doctor if you experience them. They may adjust the dose of Acetazolamide accordingly. Acetazolamide may reduce blood levels of Primidone.

Frequently asked questions

ACTAMIDE 250MG TABLET reduces the pressure inside the eyes, known as intraocular pressure. This helps to reduce the risk of damage to the optic nerve responsible for normal vision. If the pressure in the eye is not controlled, it can gradually lead to blindness. ACTAMIDE 250MG TABLET effectively controls ocular hypertension and certain types of glaucoma by decreasing the pressure in the eyes.
You should not take ACTAMIDE 250MG TABLET if you have or ever had cirrhosis, severe liver or kidney disease, an electrolyte imbalance, adrenal gland failure, or an allergy to ACTAMIDE 250MG TABLET or sulfa drugs. Also, let your doctor know if you are pregnant, planning to conceive, or are breastfeeding to avoid any harmful effects on your baby.
ACTAMIDE 250MG TABLET is effective if used in the dose and duration advised by your doctor. Do not stop taking it even if you see improvement in your condition. If you stop using ACTAMIDE 250MG TABLET too early, the symptoms may return or worsen.
No, you should not stop using ACTAMIDE 250MG TABLET suddenly without talking to your doctor. This is because if you stop the medication before completing the treatment, your symptoms may return or even worsen. Use ACTAMIDE 250MG TABLET in the dose and duration advised by your doctor to get the maximum benefit of ACTAMIDE 250MG TABLET.
If you forget a dose of ACTAMIDE 250MG TABLET, take it as soon as you remember. However, if it is almost time for your next dose, take it in the regular schedule instead of taking the missed dose. Do not double the dose to make up for the missed one, as this may increase the chances of developing side effects.

Fact Box

Chemical Class

Thiadiazole sulfonamides

Habit Forming

No

Therapeutic Class

OPHTHAL

Action Class

Carbonic Anhydrase Inhibitors (CAIs)

References

  1. Reilly RF, Jackson EK. Regulation of Renal Function and Vascular Volume. In: Brunton LL, Chabner BA, Knollmann BC,12th ed. editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 677-81.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 12-13.
  3. Acetazolamide [EMC SmPC]. London, UK: ADVANZ Pharma; 2018. [Accessed 22 Jan. 2019] (online) Available from:
  4. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 04 Apr. 2019] (online) Available from:
  5. Acetazolamide [Drug Label]. North Wales, PA: Teva Pharmaceuticals USA, Inc.; 2022. [Accessed 25 Jul. 2024] (online) Available from:
  6. Acetazolamide [Prescribing Information]. Midrand, South Africa: Adcock Ingram Limited; 2024.
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Micro Labs Ltd
Address: 27, RACE COURSE ROAD, BANGALORE-560 001, INDIA

Vendor Details

Country of origin: India
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