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Acnetoin Plus Gel is a combination medicine that is used to treats acne. It minimizes excessive oil production, thus reduces inflammation. It also prevents the growth of the microorganisms that cause acne. This also helps to prevent pimples, blackheads, and whiteheads on the skin.

Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 12 Mar 2026 | 12:42 PM (IST)
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Product introduction

Acnetoin Plus Gel is only meant for external use and should be used as advised by your doctor. A thin layer of the medicine should be applied only to the affected areas of the skin with clean and dry hands. Wash your hands before and after applying the medicine. If it gets into your eyes, nose, mouth, or vagina rinse with water. It may take several days to weeks for your symptoms to improve, but you should keep using this medicine regularly. The course of the treatment should be completed to ensure better efficacy of the medicine. If your condition does not improve or gets worse, you should talk to your doctor.

This is usually a safe medicine, however, it may cause dryness, peeling, redness, and burning sensation at the application site. These side effects are usually mild and self-limiting. Most of these side effects can be prevented by using a skin moisturizer and drinking plenty of water. Serious side effects are rare. You must consult the doctor if you experience any allergic reaction (rashes, itching, swelling, shortness of breath, etc.).

Before using this medicine, it is important to tell your doctor if you are taking or have recently taken any other medicines for the same disease or other diseases. Pregnant and breastfeeding women should use this medicine with proper consultation and caution. If you are a known allergic to the medicine, you must refrain from using this medicine and consult your doctor. During the course of the treatment, do not touch, prick or scratch the infected skin areas as this may worsen or spread the acne. Avoid unnecessary sun exposure and use a sunscreen before stepping out in the sun. It is also advised, not to receive any cosmetic procedures without asking your doctor.

Uses of Acnetoin Plus Gel

Benefits of Acnetoin Plus Gel

Treatment of Acne
Acnetoin Plus Gel helps treat and control acne or pimples. It has a mild drying effect that reduces excess oil production in the face. This helps to unblock pores and prevent further acne breakouts. It also kills and stops the growth of bacteria causing acne. Acnetoin Plus Gel usually takes a few weeks to have a noticeable effect so keep using it even if it appears not to be working. Using this medicine will help improve your mood and uplift your confidence as acne reduces.

Side effects of Acnetoin Plus Gel

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Acnetoin Plus
  • Skin peeling
  • Itching
  • Stinging sensation
  • Erythema (skin redness)
  • Burning sensation at the site of application

How to use Acnetoin Plus Gel

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the gel. Wash your hands after applying, unless hands are the affected area.

How Acnetoin Plus Gel works

Acnetoin Plus Gel is a combination of two medicines: Clindamycin and Isotretinoin which treat pimples (acne). Clindamycin is an antibiotic which works by penetrating into the skin and killing acne-causing bacteria. Isotretinoin is a form of vitamin A. It works by reducing oil production in the skin, replenishes acne-prone skin and helps keep your pores open.

Quick tips

  • It may take several weeks to show its action. Keep using it as suggested by your doctor.
  • Wash your skin with a mild cleanser and pat it dry before applying Acnetoin Plus Gel.
  • Apply it as a thin layer onto a clean, dry, unbroken infected area of skin.
  • It may cause minor burning, stinging or irritation when applied. Inform your doctor if this does not go away.
  • Avoid contact with your eyes, nose or mouth. Rinse it off with water if you accidentally get the cream in these areas.
  • Use moisturizer regularly to overcome the skin dryness during the course of treatment.

Safety advice

Alcohol

Alcohol

No interaction found/established
Pregnancy

Pregnancy

UNSAFE
Acnetoin Plus Gel is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Acnetoin Plus Gel may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

No interaction found/established
Kidney

Kidney

No interaction found/established
Liver

Liver

No interaction found/established

Frequently asked questions

Acnetoin Plus Gel is mainly used for treating moderate to severe acne by reducing bacteria and lowering oil production in the skin.
After using Acnetoin Plus Gel, you can expect some skin dryness, peeling, redness, or mild burning as the skin adjusts to this medicine.
No, avoid applying Acnetoin Plus Gel on broken, damaged, or sunburned areas to prevent irritation.
You should avoid harsh or irritating products like strong cleansers or alcohol-based items without a doctor's approval.
Acnetoin Plus Gel, by controlling acne and inflammation, can help reduce the risk of scarring over time.
Yes, Acnetoin Plus Gel increases sun sensitivity, so use sunscreen and protective clothing outdoors.

Fact Box

Habit Forming

No

Therapeutic Class

DERMA
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Leeford Healthcare Ltd
Address: 203, Mangalam, Kulupwadi, Borivali (E), Mumbai-400066

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Acnetoin Plus Gel. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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