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Clindamycin + Isotretinoin

Written By Dr. Lipika KhuranaReviewed By Dr. Rajeev Sharma
Last updated 25 Nov 2025 | 09:37 AM (UTC)

Clindamycin + Isotretinoin Uses

Clindamycin+Isotretinoin is used in the treatment of acne.

How Clindamycin + Isotretinoin works

Clindamycin + Isotretinoin is a combination of two medicines: Clindamycin and Isotretinoin which treat pimples (acne). Clindamycin is an antibiotic which works by penetrating into the skin and killing acne-causing bacteria. Isotretinoin is a form of vitamin A. It works by reducing oil production in the skin, replenishes acne-prone skin and helps keep your pores open.

Common side effects of Clindamycin + Isotretinoin

Skin peeling, Itching, Stinging sensation, Erythema (skin redness), Burning sensation at the site of application
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Expert advice for Clindamycin + Isotretinoin

  • It may take several weeks to show its action. Keep using it as suggested by your doctor.
  • Wash your skin with a mild cleanser and pat it dry before applying Clindamycin + Isotretinoin.
  • Apply it as a thin layer onto a clean, dry, unbroken infected area of skin.
  • It may cause minor burning, stinging or irritation when applied. Inform your doctor if this does not go away.
  • Avoid contact with your eyes, nose or mouth. Rinse it off with water if you accidentally get the cream in these areas.
  • Use moisturizer regularly to overcome the skin dryness during the course of treatment.