Abirat Tablet

Abiraterone Acetate (250mg)

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Abirat Tablet is used in the treatment of cancer of the prostate gland. It may also be used to treat other conditions, as determined by the doctor. It is sometimes used with certain other medicines as part of combination chemotherapy.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 25 Nov 2025 | 03:05 PM (IST)

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General Information

Contains

Abiraterone Acetate (250mg)

Marketer

Khandelwal Laboratories Pvt Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Abirat Tablet should be taken on an empty stomach, either one hour before or at least two hours after a meal. Taking it with food may increase the blood levels of Abirat Tablet, which may cause side effects. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits, but do not stop taking it unless your doctor tells you to.

The most common side effects of Abirat Tablet include vomiting, decreased potassium level in blood, edema (swelling), decreased white blood cell count, and fatigue. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. Other than this, the yellowing of the skin, loss of appetite, shortness of breath, dark urine, and nausea can happen, which indicate some liver problems. Your doctor might check you for liver function, blood pressure, and the level of potassium in your blood.

Before taking Abirat Tablet, tell your doctor if you have high blood pressure, heart problems, liver or kidney problems, or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medication, so let your doctor know about all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. It may harm your baby. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. You may be asked to undergo regular monitoring of your blood glucose level while on treatment.

Uses of Abirat Tablet

Prostate cancer

Benefits of Abirat Tablet

Prostate cancer
Prostate gland is a small walnut-sized gland that produces a fluid called seminal fluid that nourishes and transports sperms in males. The most common symptom of prostate cancer is difficulty with urination, but sometimes there are no symptoms at all. Abirat Tablet decreases or stops the growth of cancer cells by decreasing the amount of testosterone (natural hormone in males) in men. This also relieves difficulty in passing urine and makes it easier for you to urinate.

Side effects of Abirat Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Abirat

Edema (swelling)
Vomiting
Decreased potassium level in blood
Fatigue
Anemia (low number of red blood cells)
Urinary tract infection
Diarrhea
High blood pressure
Cough
Joint swelling
Nausea
Hot flashes
Headache
Increased glucose level in blood

How to use Abirat Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Abirat Tablet is to be taken on an empty stomach.

How Abirat Tablet works

Abirat Tablet works by blocking an enzyme called CYP17, which is involved in the production of androgens (male hormones like testosterone). Since many prostate cancers rely on these hormones to grow, reducing their levels helps slow down or stop the cancer's progression. Essentially, Abirat Tablet cuts off the fuel supply that the cancer needs to thrive.

All substitutes for Abirat Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Abirat Tablet is usually taken with another medicine called prednisolone to reduce unwanted side effects.
It should be taken on an empty stomach, either one hour before or at least two hours after a meal.
Always use effective birth control measures to prevent pregnancy while taking this medicine.
Your doctor may regularly monitor your liver function, blood pressure, and the level of potassium in your blood while you are having treatment with this medicine.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Abirat Tablet. Please consult your doctor.

Pregnancy

UNSAFE

Abirat Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.

Breast feeding

UNSAFE

Abirat Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

SAFE

Abirat Tablet does not usually affect your ability to drive.

Kidney

CAUTION

Abirat Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.

Liver

CAUTION

Abirat Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Abirat with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe