Abirapro 250mg Tablet is used in the treatment of cancer of the prostate gland. It may be also used to treat other conditions, as determined by the doctor. It is sometimes used with certain other medicines as part of combination chemotherapy.

Abirapro 250mg Tablet should not be taken on an empty stomach. Taking it with food may cause side effects. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include vomiting, decreased potassium level in blood, edema (swelling), decreased white blood cell count, fatigue and increased liver enzymes. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. Other than this, yellowing of skin, loss of appetite, shortness of breath, dark urine and nausea can happen, which indicate some liver problem. Your doctor might check you for liver function, blood pressure, and the level of potassium in your blood.

Before taking it, tell your doctor if have high blood pressure, heart problem, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. It may harm your baby. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. You may be asked for regular monitoring of blood glucose level while on treatment.

Uses of Abirapro Tablet

Prostate cancer

Benefits of Abirapro Tablet

In Prostate cancer

Prostate gland is a small walnut-sized gland that produces a fluid called seminal fluid that nourishes and transports sperms in males. The most common symptom of prostate cancer is difficulty with urination, but sometimes there are no symptoms at all. Abirapro 250mg Tablet decreases or stops the growth of cancer cells by decreasing the amount of testosterone (natural hormone in males) in men. This also relieves difficulty in passing urine and makes it easier for you to urinate.

Side effects of Abirapro Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Abirapro

Edema (swelling)
Vomiting
Decreased potassium level in blood
Decreased white blood cell count
Fatigue
Increased liver enzymes
Anemia (low number of red blood cells)
Urinary tract infection
Diarrhea
High blood pressure
Cough
Hypercholesterolemia (high cholesterol)
Joint swelling
Increased levels of blood fat
Altered blood sugar level

How to use Abirapro Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Abirapro 250mg Tablet is to be taken empty stomach.

How Abirapro Tablet works

Abirapro 250mg Tablet is an anticancer medication. It works by preventing androgen (male hormone) production in man. This is done by inhibiting an enzyme (CYP17) that is responsible for the production of androgen. This is how it slows down the growth of prostate cancer.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Abirapro 250mg Tablet. Please consult your doctor.

Pregnancy

UNSAFE

Abirapro 250mg Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.

Breast feeding

UNSAFE

Abirapro 250mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

SAFE

Abirapro 250mg Tablet does not usually affect your ability to drive.

Kidney

SAFE IF PRESCRIBED

Abirapro 250mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Abirapro 250mg Tablet is recommended.
Because of the limited information, cautious use of Abirapro 250mg Tablet is recommended in patients with severe kidney disease.

Liver

CAUTION

Abirapro 250mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Abirapro 250mg Tablet may be needed. Please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Abirapro 250mg Tablet

₹164.88/Tablet

Zelgor 250mg Tablet

Sun Pharmaceutical Industries Ltd

₹98.58/tablet

40% cheaper

Abitate 250mg Tablet

RPG Life Sciences Ltd

₹119.6/tablet

27% cheaper

Xbira 250mg Tablet

Cipla Ltd

₹120.81/tablet

27% cheaper

Zecyte 250mg Tablet

Cipla Ltd

₹130/tablet

21% cheaper

Abura Tablet

MSN Laboratories

₹130.33/tablet

21% cheaper

View all substitutes

Quick tips

Abirapro 250mg Tablet treats prostate cancer that has spread to other parts of the body.
It is usually taken with another medicine called prednisolone to reduce unwanted side effects.
It must be taken on an empty stomach. Don't eat any food for at least 2 hours before or 1 hour after your dose.
Always use effective birth control measures to prevent pregnancy while taking this medicine.
Your doctor may regularly monitor your liver function, blood pressure, and the level of potassium in your blood while you are having treatment with this medicine.

Fact Box

Chemical Class

Androstene Derivative

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Anticancer-others

Patient concerns

I have problem of frequent urination at night. My father had same at his time.Doctor told me that I am having BPH.Also I went through PSA whose result is 1.8 increased prostate gland size is 40 which came in ultrasound report .When doctor did some test by inserting his finger in my rectal area I felt abnormal pain.doctor asked me to go for a culture test so as to check which can be the best medicine for BPH for me. Kindly suggest if it can be something else like prostate cancer.

Dr. Vijay Sharnangat

Medical Oncology and Hematology

May not be prostate cancer, it is only begnin enlargement of prostate.

Do i have prostrate cancer. Married but now having difficulty in having relation with wife. Penis not hard in the morning. Having problem with self spontaneous erection. Please help. God Bless.

Dr. Sanjay Singh Rai

Medical Oncology and Hematology

Not a symptom of prostate cancer

User feedback

Patients taking Abirapro 250mg Tablet

Once A Day

100%

What are you using Abirapro Tablet for?

Prostate canc*

100%

*Prostate cancer

How much was the improvement?

Excellent

50%

Average

33%

Poor

17%

What were the side-effects while using Abirapro 250mg Tablet?

Urinary tract*

14%

Vomiting

14%

Headache

14%

Joint pain

14%

High blood pr*

14%

*Urinary tract infection, High blood pressure

How do you take Abirapro Tablet?

With food

100%

Please rate Abirapro 250mg Tablet on price

Expensive

78%

Average

22%

FAQs

Q. Can Abirapro 250mg Tablet cure prostate cancer?

Abirapro 250mg Tablet does not cure cancer but helps in prolonging and improving the life of the patient. Moreover, when prostate cancer is treated with Abirapro 250mg Tablet then the frequency of fractures is relatively less. Similarly, the increase in pain is less common with Abirapro 250mg Tablet.

Q. Is Abirapro 250mg Tablet a chemotherapy drug?

Abirapro 250mg Tablet is a hormonal treatment not a chemotherapy drug. It is used to treat prostate cancer in adult men that has spread to other parts of the body. Abirapro 250mg Tablet stops your body from making testosterone. This can slow down the growth of prostate cancer.

Q. Why do I need to take prednisolone with Abirapro 250mg Tablet?

Your doctor will always prescribe prednisolone with Abirapro 250mg Tablet. Taking these two medicines together lowers the risk of getting high blood pressure, fluid retention (having too much water in your body), or having reduced levels of potassium in your blood, which can occur due to Abirapro 250mg Tablet.

Q. Does Abirapro 250mg Tablet affect liver?

Abirapro 250mg Tablet can cause severe liver problems. In very rare cases, Abirapro 250mg Tablet may even cause failure of the liver to function (called acute liver failure), which can even lead to death. Tell your doctor if you experience yellowing of the skin or eyes, darkening of the urine, or severe nausea or vomiting, as these could be signs or symptoms of liver problems.

Q. How frequently should the liver investigations be done?

Liver enzymes should be measured prior to starting the treatment, every two weeks for the first three months into the treatment, and monthly thereafter. If you develop clinical symptoms or signs suggestive of liver toxicity, liver enzymes should be measured immediately. If the liver enzyme levels are increased beyond certain levels, your doctor may temporarily discontinue the treatment with Abirapro 250mg Tablet.

Q. How to take Abirapro 250mg Tablet?

Abirapro 250mg Tablet should be taken on an empty stomach with water 1 hour before eating or at least 2 hours after eating. Taking it with food may cause increased and variable levels of Abirapro 250mg Tablet in your blood which can be harmful. Remember not to crush or chew the tablet.

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Prostate Specific Antigen (Total) PSA

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 4-5.
Abiraterone acetate. High Wycombe, Buckinghamshire: Janssen-Cilag Ltd.; 2017. [Accessed 26 Mar. 2019] (online) Available from:
Abiraterone Acetate. Patheon Inc.: Mississauga, Canada; 2011 [revised May 2016]. [Accessed 26 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:

Manufacturer/Marketer address

Glenmark Pharmaceuticals Limited, B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai – 400 026.

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.