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6-MP 50mg Tablet

Mercaptopurine (50mg)

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6-MP 50mg Tablet is used in the treatment of blood cancer. It works by decreasing the number of red blood cells that are produced by the body. Thereby preventing the cancer cells from growing and multiplying.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 29 Apr 2026 | 01:01 PM (IST)

₹52.8

₹56.06

6% off

10 tablets

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General Information

Contains

Mercaptopurine (50mg)

Marketer

Zydus Lifesciences Ltd

Storage

Store below 25°C

The content is shown in English

Product introduction

6-MP 50mg Tablet can be taken with or without food, or you can have it one hour before or two hours after the meal. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits, but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include nausea, vomiting, rash, diarrhea, and loss of appetite. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby increasing your susceptibility to infections. Regular blood tests are required to check your blood cells, along with heart, liver, and blood uric acid levels. You have to avoid driving or attention-seeking activities if you experience dizziness while taking this medicine.

Before taking it, tell your doctor if you have heart disease, liver or kidney problems, or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine, so let your doctor know about all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of 6-MP Tablet

Treatment of Blood cancer

Benefits of 6-MP Tablet

Treatment of Blood cancer
Blood cancer, also called leukemia, is a cancer of the blood-forming tissues that decreases the body's ability to fight infection. 6-MP 50mg Tablet kills or stops the growth of cancer cells and prevents the multiplication of cancer cells. It is an effective medicine, but you should discuss the side effects and benefits of this medicine with your doctor. Let your doctor know if any of the side effects bother you.

Side effects of 6-MP Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of 6-MP

Nausea
Vomiting
Rash
Decreased white blood cell count (neutrophils)
Intestinal ulcer
Anemia (low number of red blood cells)
Increased bilirubin in the blood
Low blood platelets
Increased transaminase level in blood
Diarrhea
Loss of appetite

How to use 6-MP Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. 6-MP 50mg Tablet may be taken with or without food.

How 6-MP Tablet works

6-MP 50mg Tablet interferes with the growth of DNA and RNA of the cancer cells by substituting their building blocks. It prevents the cancer cells from growing and multiplying.

Quick tips

Do not drive or do anything requiring concentration until you know how it affects you.
Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine.
Your doctor may get regular blood and urine tests done to monitor your blood cells and kidney and liver function during treatment with this medicine.
Inform your doctor immediately if you notice any signs of infection, such as fever, sore throat, rash, or severe diarrhea.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with 6-MP 50mg Tablet. Please consult your doctor.

Pregnancy

UNSAFE

6-MP 50mg Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.

Breast feeding

UNSAFE

6-MP 50mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

CONSULT YOUR DOCTOR

It is not known whether 6-MP 50mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney

CAUTION

6-MP 50mg Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

CAUTION

6-MP 50mg Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
Inform your doctor if you develop any signs and symptoms of jaundice while taking this medicine.

Interaction with drugs

Taking 6-MP with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Filgrastim (Injection Route)

Do not consume Filgrastim from 24 hours before or 24 hours after taking Mercaptopurine. Please consult with your doctor. Mercaptopurine may reduce the efficacy of Filgrastim.

Severe

Pegfilgrastim (Injection Route)

Do not consume Mercaptopurine from 14 days before until 24 days after taking Pegfilgrastim. Please consult your doctor.

Severe

Sargramostim (Injection Route)

Do not consume Mercaptopurine from 1 day before until 1 day after taking Sargramostim. Please consult your doctor.

Severe

Lenograstim (Injection Route)

Do not consume Lenograstim from 24 hours before until 24 hours after undergoing cytotoxic chemotherapy.

Severe

Molgramostim (Injection Route)

Do not consume Mercaptopurine from 1 day before until 1 day after taking Molgramostim. Please consult your doctor.

Frequently asked questions

What is 6-MP 50mg Tablet used for?

6-MP 50mg Tablet is a chemotherapy medicine used to treat a blood cancer called acute lymphoblastic leukemia (ALL). It helps stop the growth of cancer cells and is often used during the maintenance phase of treatment.

What are the serious side effects of 6-MP 50mg Tablet?

Serious side effects of 6-MP 50mg Tablet include low blood counts (increasing risk of infection, bleeding, or anemia), liver damage (jaundice, stomach pain), new types of cancer (like lymphoma), and severe infections. Contact your doctor if you notice signs like yellowing of the skin or eyes, bruising easily, or fever.

Can 6-MP 50mg Tablet cause birth defects?

Yes, 6-MP 50mg Tablet can harm an unborn baby. Women who are pregnant or trying to get pregnant should avoid this medication. Use effective birth control during the treatment and for a few months (6 months for women, 3 months for men) after the treatment.

What tests might be needed before taking 6-MP 50mg Tablet?

Your doctor may test for certain gene (TPMT or NUDT15) deficiencies, which affect how your body breaks down 6-MP 50mg Tablet. If you have a deficiency, you may need a lower dose to avoid serious side effects like low blood cell counts.

Can 6-MP 50mg Tablet cause new cancers?

In rare cases, yes. 6-MP 50mg Tablet can increase the risk of secondary cancers such as lymphoma, especially when used with other immune-suppressing medications.

Does 6-MP 50mg Tablet cause hair loss?

6-MP 50mg Tablet may cause hair loss or thinning. However, this side effect is not so common but is possible depending upon the condition, its severity, dose, and duration. Higher doses and/or longer duration may increase the chance of hair loss.

How long does 6-MP 50mg Tablet take to show results?

The exact time 6-MP 50mg Tablet takes to show results is not known. However, you may start experiencing some improvement in your symptoms in a few months or with regular prescribed usage.

Does 6-MP 50mg Tablet affect my liver?

Liver toxicity is a common side effect of 6-MP 50mg Tablet. Your doctor may frequently perform liver function tests during 6-MP 50mg Tablet treatment and may modify the 6-MP 50mg Tablet dose based on the liver enzyme levels.

Why am I not feeling hungry after taking 6-MP 50mg Tablet?

Loss of appetite is a common side effect of 6-MP 50mg Tablet treatment. Inform your doctor if it becomes severe or if you notice any weight loss.

How to store 6-MP 50mg Tablet?

You should store 6-MP 50mg Tablet below room temperature. Keep 6-MP 50mg Tablet in a child-resistant container away from light and moisture. Additionally, 6-MP 50mg Tablet is a toxic medicine and special handling procedures should be followed as mentioned in the package label/insert.

Fact Box

Chemical Class

Purinethiones

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Antimetabolites

Related lab tests

Complete Blood Count

Peripheral Smear Examination

References

Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 948.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 864-66.
Mercaptopurine. Dublin, Ireland: Aspen; 2012 [revised 17 Dec. 2018]. [Accessed 29 Jan. 2019] (online) Available from:
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Mercaptopurine. [Updated 2020 Jan 20]. [Accessed 18 Feb. 2020] (online) Available from:
Mercaptopurine monohydrate [Product Information]. Dublin, Ireland: Nova Laboratories Ireland Ltd.; [Accessed 02 Apr. 2025] (online) Available from:
Mercaptopurine monohydrate [Product Information]. Berkeley Heights, NJ: Hikma Pharmaceuticals USA Inc.; [Accessed 02 Apr. 2025] (online) Available from:

User feedback

Patients taking 6-MP 50mg Tablet

Once A Day

100%

What are you using 6-MP Tablet for?

Blood cancer

71%

Others

26%

Ovarian cancer

How much was the improvement?

Excellent

57%

Average

32%

Poor

12%

What were the side-effects while using 6-MP 50mg Tablet?

Decreased white blood cell count (neutrophils)

33%

Nausea

33%

Vomiting

17%

No Side Effect

17%

How do you take 6-MP Tablet?

Empty stomach

67%

With food

33%

Please rate 6-MP 50mg Tablet on price

Not Expensive

46%

Expensive

33%

Average

21%

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Zydus Lifesciences Ltd
Address: Zydus Tower, Satellite Cross Roads,Ahmedabad – 380015 Gujarat, India.

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver 6-MP 50mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

Why we need a prescription?

6-MP 50mg Tablet

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General Information

Contains

Marketer

Storage

Product introduction

Uses of 6-MP Tablet

Benefits of 6-MP Tablet

Side effects of 6-MP Tablet

How to use 6-MP Tablet

How 6-MP Tablet works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Filgrastim (Injection Route)

Pegfilgrastim (Injection Route)

Sargramostim (Injection Route)

Lenograstim (Injection Route)

Molgramostim (Injection Route)

Frequently asked questions

What is 6-MP 50mg Tablet used for?

What are the serious side effects of 6-MP 50mg Tablet?

Can 6-MP 50mg Tablet cause birth defects?

What tests might be needed before taking 6-MP 50mg Tablet?

Can 6-MP 50mg Tablet cause new cancers?

Does 6-MP 50mg Tablet cause hair loss?

How long does 6-MP 50mg Tablet take to show results?

Does 6-MP 50mg Tablet affect my liver?

Why am I not feeling hungry after taking 6-MP 50mg Tablet?

How to store 6-MP 50mg Tablet?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Complete Blood Count

Peripheral Smear Examination

References

User feedback

Patients taking 6-MP 50mg Tablet

What are you using 6-MP Tablet for?

How much was the improvement?

What were the side-effects while using 6-MP 50mg Tablet?

How do you take 6-MP Tablet?

Please rate 6-MP 50mg Tablet on price

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

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