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Neurokem 50 Capsule

Pregabalin (50mg)

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Neurokem 50 Capsule is a medicine used to relieve pain caused by nerve damage (neuropathic pain). The pain is caused by diabetes, shingles (herpes zoster infection), spinal cord injury, or other conditions. It is also used to treat widespread muscle pain and stiffness in people with fibromyalgia.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 12 May 2026 | 02:37 PM (IST)

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General Information

Contains

Pregabalin (50mg)

Marketer

Alkem Laboratories Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Neurokem 50 Capsule can be taken with or without food. The dose and duration of treatment may depend on the severity of your condition and your response to it. Your doctor may start this medicine at a low dose and gradually increase it. It may take a few weeks for the medicine to work properly. Follow your doctor’s instructions and continue taking it regularly until your doctor advises you to stop. The side effects of this medicine are usually mild and go away on their own. The most common ones are feeling sleepy or dizzy, dry mouth, blurred vision, weight gain, edema (swelling throughout the body), and difficulty concentrating. Let your doctor know if any of these side effects persist or worsen. Before taking Neurokem 50 Capsule, tell your doctor if you are pregnant, breastfeeding, or planning to become pregnant. Be careful while driving, as sleepiness, dizziness, and blurred vision may be seen as side effects. You should avoid drinking alcohol along with this medicine, as it may lead to excessive sleepiness and dizziness.

Uses of Neurokem Capsule

Treatment of Neuropathic pain : Neurokem 50 Capsule helps relieve pain associated with nerve damage or irritation. This includes pain associated with diabetes, shingles, spinal cord injury, or spinal nerve compression.
Treatment of Fibromyalgia : Neurokem 50 Capsule helps manage widespread musculoskeletal pain, tenderness, and stiffness. It also helps manage symptoms such as persistent fatigue, sleep disturbances, difficulty concentrating, and increased sensitivity to pain or touch.

Benefits of Neurokem Capsule

Treatment of Neuropathic pain
Neurokem 50 Capsule works by calming overactive nerve signals and reducing abnormal pain transmission in the brain. This helps relieve symptoms such as burning, tingling, shooting pain, and numbness.

Treatment of Fibromyalgia
Neurokem 50 Capsule helps decrease pain intensity and improve symptoms such as tenderness and sleep problems. When used regularly, it can support better physical function and reduce symptom flare-ups.

Side effects of Neurokem Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Neurokem

Dizziness
Sleepiness
Dryness in mouth
Edema (swelling)
Blurred vision
Weight gain
Abnormal thoughts

How to use Neurokem Capsule

Take this medicine in the dose and duration as advised by your doctor. Neurokem 50 Capsule may be taken with or without food.

How Neurokem Capsule works

Neurokem 50 Capsule is an antiepileptic medication. When given for epilepsy, it is believed to work by reducing the abnormal electrical activity in the brain, thus preventing seizures. It is also used to treat nerve and muscle pain where it blocks pain by interfering with pain signals traveling through the damaged nerves and the brain.

All substitutes for Neurokem 50 Capsule

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Neurokem 50 Capsule should be taken exactly as per the dose and duration prescribed by your doctor.
It may cause sleepiness. Do not drive or perform any activity that requires concentration until you know how it affects you.
It may cause blurring or loss of vision. Inform your doctor immediately if you notice any changes in your vision.
Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior.
Do not stop taking the medication suddenly. This can lead to withdrawal symptoms such as anxiety, agitation, insomnia, and, in some cases, seizures.
Avoid alcohol completely while taking this medication. Combining it with alcohol can significantly depress the central nervous system. This leads to excessive sedation, impaired coordination, and respiratory depression (slowed or shallow breathing).

Safety advice

Alcohol

UNSAFE

Do not drink alcohol while you are taking this medicine. Neurokem 50 Capsule may cause excessive drowsiness when taken with alcohol.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Neurokem 50 Capsule during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CONSULT YOUR DOCTOR

Neurokem 50 Capsule may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

UNSAFE

Neurokem 50 Capsule may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Neurokem 50 Capsule should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.

Liver

SAFE IF PRESCRIBED

Neurokem 50 Capsule is safe to use in patients with liver disease. No dose adjustment is recommended.

Interaction with drugs

Taking Neurokem with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Moderate

Orlistat (Oral Route)

Watch out for symptoms such as tremors. seizures or impaired coordination and consult your doctor if you experience them. Your doctor may consider separating the administration of Orlistat and Pregabalin. Orlistat may reduce efficacy of Pregabalin.

Moderate

Clozapine (Oral Route)

If concurrent use is essential, watch out for symptoms of Clozapine side effects such as blurred vision, sleepiness, headache, constipation, nausea, dizziness, faintness or fatigue and consult your doctor if you experience them. They may adjust the dose of Clozapine accordingly. Clozapine may raise blood levels of the active form of Pregabalin.

Moderate

Buprenorphine (Injection Route)

If concurrent use is essential, watch out for symptoms of Buprenorphine side effects such as drowsiness, excessive sedation, tiredness, dizziness or slurred speech and consult your doctor if you experience them. They may adjust the dose of Buprenorphine as per the observations. It is advised to avoid driving or undertaking other tasks requiring skill and alertness.

Moderate

Buprenorphine (Oral Route)

Moderate

Buprenorphine (Transdermal Route)

Frequently asked questions

What is Neurokem 50 Capsule, and what is it used for?

Neurokem 50 Capsule is an anticonvulsant and pain-relieving medicine that contains pregabalin. It is used to treat neuropathic (nerve-related) pain and fibromyalgia, a condition characterized by widespread pain, fatigue, and sleep disturbances. It works by calming overactive nerve signals in the brain, which reduces abnormal pain transmission. This helps relieve symptoms such as burning, tingling, and shooting pain. It also reduces pain sensitivity, improves sleep, and eases fatigue in people with fibromyalgia.

I have been prescribed Neurokem 50 Capsule for pain due to shingles. When can I expect relief from pain?

Some people may notice improvement within the first week of treatment. However, full pain relief may take several weeks. Response varies from person to person. Your doctor may gradually adjust the dose to improve effectiveness while minimizing side effects.

For how long can I take Neurokem 50 Capsule, and is it safe for long-term use?

Neurokem 50 Capsule may be used for both short-term and long-term treatment, depending on the condition being treated. For chronic nerve pain, your doctor may prescribe it for extended periods if it continues to provide benefit. Regular follow-up is usually advised to assess effectiveness, side effects, and the ongoing need for treatment.

Is Neurokem 50 Capsule addictive?

Neurokem 50 Capsule has the potential for misuse and dependence. It should be used with caution, particularly in people with a history of substance abuse. Your doctor may monitor you for signs and symptoms of pregabalin misuse, abuse, or dependence, such as the development of tolerance (needing higher doses), dose escalation, and drug-seeking behaviour.

Can I take diazepam and Neurokem 50 Capsule together?

Do not take these two medicines together without consulting your doctor. Caution is required when taking Neurokem 50 Capsule with diazepam or other medicines that slow down the central nervous system. Both medicines can cause drowsiness, dizziness, and slowed breathing. When combined, these effects can increase the risk of serious side effects, including breathing problems.

When is the best time to take Neurokem 50 Capsule?

Neurokem 50 Capsule is usually taken once or twice daily, depending on the dose prescribed by your doctor. It can be taken at any time of day, but it's best to take it at the same time each day to maintain a consistent medication level in your body. Some individuals prefer taking it in the evening because it may cause dizziness or sleepiness.

Who cannot take Neurokem 50 Capsule?

Neurokem 50 Capsule should not be taken by individuals who are allergic to pregabalin or any of its components. It is not typically recommended during pregnancy unless the potential benefits outweigh the risks. Caution is needed in people with kidney disease (dose adjustment may be required), a history of substance misuse, heart-related problems, or breathing disorders.

What are the long-term side effects of Neurokem 50 Capsule?

Common side effects of Neurokem 50 Capsule include dizziness, sleepiness, dry mouth, swelling of the hands or feet (peripheral edema), blurred vision, and weight gain. These may persist during long-term use in some individuals. Long-term treatment requires monitoring for weight changes, swelling, mood symptoms, and overall effectiveness.

Fact Box

Chemical Class

Gamma amino acid derivative

Habit Forming

Therapeutic Class

NEURO CNS

Action Class

Alpha-2 Delta Ligands- Antiepileptic Drugs (AEDs)

References

Stahl SM, editor. Pregabalin. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 557-60.
McNamara JO. Pharmacotherapy of the Epilepsies. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 599.
Porters RJ, Meldrum BS. Antiseizure Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 410.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1149.
Pregabalin. Vega Baja, Puerto Rico: Pfizer Pharmaceuticals LLC; 2009. [Accessed 23 Jan. 2019] (online) Available from:
Pregablin. New York, New York: Pfizer; 2004 [revised Jun. 2011]. [Accessed 22 Mar. 2019] (online) Available from:
Pregabalin. Sandwich, Kent: Pfizer Limited; 2009 [revised July 2018]. [Accessed 22 Mar. 2019] (online) Available from:
Pregabalin. Beverley, Hull: Dr. Reddy's Laboratories (UK) Ltd.; 2015 [revised 01 May 2018]. [Accessed 17 Jun. 2019]. (online) Available from:
National Health Service. Pregabalin; 2018. [Accessed 17 Jun. 2019] (online) Available from:
Lyrica (pregabalin): Frequently asked questions. [Accessed 17 Jun. 2019]. (online) Available from:
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Pregabalin. [Updated 2019 Oct 23]. [Accessed 20 Feb. 2020] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 22 Mar. 2019] (online) Available from:
Pregabalin [Package Insert]. Solan, Himachal Pradesh: Torrent Pharmaceuticals Ltd. [Accessed 05 Aug. 2023] (online) Available from:
Pregabalin [Prescribing Information]. India: Alembic Pharmaceuticals Limited; 2023. [Accessed 05 Aug. 2023] (online) Available from:
Pregabalin. Prescribing Information. Viatris Specialty LLC. 2025. [Accessed 10 Sep. 2025] (online) Available from:
Pregabalin [Prescribing Information]. Morgantown, WV: Viatris Specialty LLC; 2025. [Accessed 06 Nov. 2025] (online). Available from:

User feedback

Patients taking Neurokem 50 Capsule

Once A Day

100%

What are you using Neurokem Capsule for?

Neuropathic pain

100%

How much was the improvement?

Excellent

100%

What were the side-effects while using Neurokem 50 Capsule?

No Side Effect

100%

How do you take Neurokem Capsule?

With food

100%

Please rate Neurokem 50 Capsule on price

Expensive

67%

Average

33%

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Alkem Laboratories Ltd
Address: Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Neurokem 50 Capsule. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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Neurokem 50 Capsule

Neurokem 50 Capsule

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Neurokem Capsule

Benefits of Neurokem Capsule

Side effects of Neurokem Capsule

How to use Neurokem Capsule

How Neurokem Capsule works

All substitutes for Neurokem 50 Capsule

Maxgalin 50 Capsule

pregabID 50 Capsule

Pbren 50 Capsule

Pregaba 50 Capsule

preGAlin 50 Capsule

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Orlistat (Oral Route)

Clozapine (Oral Route)

Buprenorphine (Injection Route)

Buprenorphine (Oral Route)

Buprenorphine (Transdermal Route)

Frequently asked questions

What is Neurokem 50 Capsule, and what is it used for?

I have been prescribed Neurokem 50 Capsule for pain due to shingles. When can I expect relief from pain?

For how long can I take Neurokem 50 Capsule, and is it safe for long-term use?

Is Neurokem 50 Capsule addictive?

Can I take diazepam and Neurokem 50 Capsule together?

When is the best time to take Neurokem 50 Capsule?

Who cannot take Neurokem 50 Capsule?

What are the long-term side effects of Neurokem 50 Capsule?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

User feedback

Patients taking Neurokem 50 Capsule

What are you using Neurokem Capsule for?

How much was the improvement?

What were the side-effects while using Neurokem 50 Capsule?

How do you take Neurokem Capsule?

Please rate Neurokem 50 Capsule on price

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

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