SLA (Soluble Liver Antigen) Antibody Detection

Also referred as

Anti-Soluble Liver Antigen (SLA) Test

For men & women

Earliest reports in

192 hours

Contains

1 test

Test price:

₹2749

~~₹3050~~

10% off

Get it at ₹2474 with coupon

Apply coupon 1MGNEWG during checkout

More offers available

Know more about this test

The SLA (Soluble Liver Antigen) Antibody Detection test is a blood test used to detect the presence of anti-SLA antibodies, which are often found in individuals with autoimmune hepatitis. This test helps in the diagnosis and management of autoimmune liver diseases, particularly type 1 autoimmune hepatitis (AIH).

Samples required

Blood

Find out

Why is this test booked?

Preparations

No special preparation is required.

Sample Collection

Who will collect your samples?

Conducted by

NABL accredited partner lab

Accredited labs

Highly skilled Phlebos

Verified reports

Who will collect your samples?

Tata 1mg certified phlebotomists

Understanding SLA (Soluble Liver Antigen) Antibody Detection

Anti-soluble liver antigen (SLA) is an autoantibody often present in the blood of individuals with autoimmune liver diseases, especially autoimmune hepatitis (AIH). Autoimmune hepatitis is a chronic condition in which the body’s immune system attacks liver cells, leading to ongoing inflammation. If left untreated, this may progress to cirrhosis, liver failure, or even liver cancer.

The SLA (Soluble Liver Antigen) Antibody Detection test is used to detect these specific antibodies in the blood and is particularly valuable in identifying a subset of autoimmune hepatitis patients who do not show other typical autoantibodies, such as antinuclear antibodies (ANA) or smooth muscle antibodies (SMA). Anti-SLA antibodies are highly specific for autoimmune hepatitis; their presence strongly supports the diagnosis and helps distinguish AIH from other liver disorders such as viral hepatitis, drug-induced hepatitis, or fatty liver disease.

Doctors may recommend this test if you experience symptoms like unexplained fatigue, jaundice (yellowing of skin and eyes), abdominal discomfort, joint pain, or dark urine, or if liver function tests (LFTs) show unexplained abnormalities. Early detection through this test allows timely treatment, which is crucial in preventing long-term complications.

No special preparation is needed for getting the SLA (Soluble Liver Antigen) Antibody Detection test done. However, be sure to inform the doctor about any medications or supplements being taken, as they may affect the test results.

Lab test results may vary across different laboratories. Abnormal test results require expert interpretation. Therefore, never try to self-medicate based solely on these results. Always consult a doctor for a proper understanding of the test results.

Please note: This is an outsourced test. The sample for this test is collected by TATA 1MG and processed at an NABL accredited partnered lab.

What does SLA (Soluble Liver Antigen) Antibody Detection measure?

The SLA (Soluble Liver Antigen) Antibody Detection test measures the presence of anti-SLA/LP antibodies in the blood. These antibodies are directed against soluble liver antigen, a protein associated with liver and pancreatic cells. Their presence is considered highly specific for autoimmune hepatitis, with very few false positives.

Detection of Anti-SLA antibodies indicates that the immune system is attacking the liver, causing chronic inflammation and damage. This information helps doctors confirm autoimmune hepatitis, decide on the need for immunosuppressive treatment, and rule out other potential causes of liver dysfunction.

A positive result strongly supports autoimmune hepatitis, while a negative result does not completely rule it out, as some patients may test negative for anti-SLA but positive for other autoimmune markers.

Test Information is reviewed by: Dr. K Madhuri Reddy, MD Pathology, MBBS and written by Shweta Prakash, MSc, BSc . The test details are for information purpose only. Consult a doctor before taking any test. Last updated on: 26th Aug 2026

Did you find information useful ?

YES

SLA (Soluble Liver Antigen) Antibody Detection test price for other cities

Price in	Bangalore	Rs. 2639
Price in	New Delhi	Rs. 2749
Price in	Mumbai	Rs. 2899
Price in	Kolkata	Rs. 2639
Price in	Pune	Rs. 2649

Book a Good Health Gold Package with Smart Report test at home near me

Easy online booking

Search for tests and packages, book your preferred time slot and enter your address for seamless at-home lab tests.

Live tracking of phlebotomist

Track our trained phlebotomist's real time location for seamless sample collection.

Safe Sample Collection

Our phlebotomists follow strict safety protocols to collect samples safely at home and on time.

Sample received at lab

Samples are transported securely to our accredited labs with world-class machines for testing by qualified experts.

Quick, Doctor-Verified Reports

Get doctor-approved reports via email and WhatsApp, with options for doctor follow-ups and AI insights.

FAQs related to SLA (Soluble Liver Antigen) Antibody Detection

What is the SLA (Soluble Liver Antigen) Antibody Detection test?

It is a blood test that detects anti-soluble liver antigen antibodies, which are linked to autoimmune hepatitis and certain autoimmune liver diseases.

Why is the SLA (Soluble Liver Antigen) Antibody Detection test important?

This test is highly specific for autoimmune hepatitis and helps confirm diagnosis, especially when other common liver antibodies are absent.

Who should get the SLA (Soluble Liver Antigen) Antibody Detection test?

People with unexplained liver enzyme abnormalities, symptoms of liver disease (fatigue, jaundice, dark urine, abdominal pain), or suspected autoimmune hepatitis may be advised to take this test.

How is the SLA (Soluble Liver Antigen) Antibody Detection test performed?

A small blood sample is taken from a vein in your arm and sent to a specialized lab for antibody detection.

What does a positive result indicate?

A positive result strongly suggests autoimmune hepatitis and may indicate a more severe form of the disease that requires medical management.

What should I do if I test positive for anti-SLA?

Consult a doctor for further evaluation and treatment. Do not start or stop any medicines without medical guidance.

What other tests may be performed along with the SLA (Soluble Liver Antigen) Antibody Detection test?

Liver function tests (LFTs), ANA, SMA, LKM antibody tests, a viral hepatitis panel, and sometimes a liver biopsy are done to confirm the diagnosis.

Is the SLA (Soluble Liver Antigen) Antibody Detection test specific for autoimmune hepatitis?

Yes, Anti-SLA antibodies are considered highly specific for autoimmune hepatitis and are rarely seen in other conditions.

Can anti-SLA levels change over time?

Yes. Antibody levels may fluctuate, but once positive, they usually remain detectable even if symptoms improve.

What are the symptoms of autoimmune hepatitis?

Common symptoms include fatigue, jaundice, joint pain, abdominal discomfort, loss of appetite, and dark urine. Some people may have no symptoms in the early stages.

Can lifestyle changes affect autoimmune hepatitis?

A healthy diet, avoiding alcohol, regular monitoring, and following prescribed medication help manage the condition, but lifestyle changes alone cannot cure it.

Can autoimmune hepatitis be cured?

Currently, there is no complete cure, but with proper treatment, the disease can be well-controlled, liver damage can be minimized, and long-term outcomes can improve significantly.

How does Tata 1mg ensure accurate lab test results?

Tata 1mg ensures accurate lab test results through certified laboratories that use advanced technology and adhere to stringent quality control measures. This commitment to high standards guarantees reliable results.

Need help?