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Multiple Myeloma Comprehensive Panel Quantitative, Serum

Multiple Myeloma Comprehensive Panel Quantitative, Serum near me in New Delhi

Also referred as
Comprehensive Multiple Myeloma Panel
For men & women
Earliest reports in
96 hours
Contains
9 tests
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The Multiple Myeloma Comprehensive Panel Quantitative, Serum is a detailed blood test that evaluates abnormal proteins and specific markers produced by plasma cells in the bone marrow. The panel includes several components: Serum Protein Electrophoresis (SPEP), Serum Immunofixation Electrophoresis (SIFE), Immunoglobulin Profile (IgG, IgA, and IgM), Free Light-chain assay, and Beta-2 Microglobulin. SPEP identifies abnormal protein levels in the blood, while SIFE further characterizes the specific type of abnormal proteins. Immunoglobulin Profile determines the levels of different immunoglobulins. The Free Light-chain assay quantifies light chains produced by myeloma cells. Beta-2 Microglobulin is a marker of disease burden. These tests aid in diagnosing multiple myeloma, assessing disease stage, and monitoring response to treatment, enabling personalized and effective management of patients with multiple myeloma.  This panel is widely available with Tata 1mg labs at an affordable price in New Delhi. 

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Understanding Multiple Myeloma Comprehensive Panel Quantitative, Serum

Multiple myeloma (MM) is a type of blood cancer that arises from plasma cells, a type of white blood cell responsible for fighting infections. In multiple myeloma, abnormal plasma cells accumulate in the bone marrow and produce proteins called M-proteins, which can disrupt normal blood and organ function. Common symptoms include bone pain, weakness, fatigue, weight loss, poor appetite, nausea, and constipation. Risk factors include increasing age, male gender, family history, and a history of monoclonal gammopathy of undetermined significance (MGUS).

The Multiple Myeloma Comprehensive Panel Quantitative, Serum includes several tests including Serum Protein Electrophoresis (SPEP), Serum Immunofixation Electrophoresis (SIFE), Immunoglobulin Profile (IgG, IgA, IgM), Free Kappa and Lambda light chains with Kappa/Lambda ratio, and Beta-2 Microglobulin. SPEP identifies abnormal protein levels in the blood, while SIFE characterizes the type of abnormal proteins. The immunoglobulin profile evaluates the levels of IgG, IgA, and IgM, and the free light chain assay measures the free Kappa and Lambda chains, which are often elevated in multiple myeloma. Beta-2 Microglobulin serves as a marker of disease burden and helps assess prognosis.

This comprehensive panel enables doctors to detect multiple myeloma early, classify disease stage, monitor response to therapy, and identify patients at higher risk of aggressive disease. By providing a detailed molecular and protein profile, this test supports personalized treatment planning and effective disease management.

Doctors may recommend this test for patients who present with symptoms like bone pain, fatigue, anemia, or abnormal kidney function, or for those who need monitoring after a previous diagnosis of multiple myeloma or related plasma cell disorders. 

For this test, it is important to submit the clinical history, histopathology report, previous test results, and a doctor’s prescription at the time of sample collection. The Tata 1mg consolidated Test Requisition Form (TRF) must also be duly filled and submitted.

Lab test results may vary across different laboratories. Abnormal test results require an expert interpretation. Therefore, never try to self-medicate at home based solely on these results, and always consult a doctor for proper understanding of the test results.

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What does Multiple Myeloma Comprehensive Panel Quantitative, Serum measure?

Contains 9 tests

The Multiple Myeloma Comprehensive Panel Quantitative, Serum measures abnormal proteins and biomarkers produced by malignant plasma cells including.

Serum Protein Electrophoresis (SPEP): Detects abnormal protein levels in the blood.

Serum Immunofixation Electrophoresis (SIFE): Identifies the type of abnormal M-proteins.

Immunoglobulin Profile (IgG, IgA, IgM): Evaluates levels of major antibodies.

Free Kappa and Lambda Light Chains, Kappa/Lambda Ratio: Measures light chains produced by plasma cells and detects imbalances associated with disease.

Beta-2 Microglobulin: Acts as a marker of disease burden and prognosis.

By combining these tests, doctors can accurately diagnose multiple myeloma, monitor disease activity, assess treatment response, and make informed decisions about therapy. This panel helps ensure that treatment is tailored to the individual patient’s disease profile for better outcomes.

Immunofixation Electrophoresis Serum

The Immunoglobulin A test measures the concentration of IgA antibodies in the blood. The immune system produces these antibodies in response to pathogens and is primarily active in the mucosal membranes of the body, where they help prevent infections. Elevated levels of IgA may indicate chronic infections, autoimmune conditions, or inflammation, while lower levels can suggest immunodeficiency or impaired antibody production. This test provides essential insight into an individual’s mucosal immune health and is important for diagnosing and managing immune-related conditions.

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The Immunoglobulin M test measures the concentration of IgM antibodies in the blood. These antibodies are typically the first line of defense produced by the immune system during an initial exposure to a pathogen (bacteria, virus, etc). Elevated IgM levels indicate a recent or ongoing infection, while low or absent IgM levels suggest that an individual is either not currently infected or that the immune system has entered a later phase of response. This test is particularly useful for diagnosing acute infections and for distinguishing between new and past infections. 

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Beta 2 Microglobulin, Serum

The Immunoglobulin G test measures the concentration of IgG antibodies present in the serum. These antibodies are produced by the immune system in response to specific pathogens or infections. Elevated levels of IgG can indicate recent or chronic infections, while lower levels may suggest an impaired immune response or deficiency. This test is crucial for assessing an individual’s immune status and provides valuable information for doctors to make informed clinical decisions regarding diagnosis, treatment strategies, and ongoing management of various health conditions.

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Free Kappa
Free Lambda

The Kappa/Lambda Ratio test measures the balance of two types of free light chains: free kappa light chains and free lambda light chains. These light chains are components of antibodies produced by plasma cells as part of the immune response. Normally, a small amount of free light chains are present in the bloodstream, but in some conditions, such as plasma cell disorders like primary amyloidosis, multiple myeloma, Waldenström macroglobulinemia, and monoclonal gammopathies, the production of these light chains can rise significantly. 

By considering the balance between kappa and lambda light chains, rather than just their individual levels, the Kappa/Lambda Ratio test provides a more comprehensive assessment of light chain production and its relevance to diagnosing plasma cell proliferation. 

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The Protein Electrophoresis, Serum test measures the concentration and distribution of specific proteins (like albumin, alpha globulins, beta globulins, and gamma globulins) in the blood. Each of these plays a vital role in bodily functions. This test aids in the detection of abnormal proteins, particularly monoclonal (M) proteins. The presence of M proteins may indicate plasma cell disorders such as multiple myeloma (a blood cancer that affects plasma cells in the bone marrow). Also, this test helps diagnose and monitor various blood disorders.

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Multiple Myeloma Comprehensive Panel Quantitative, Serum test price for other cities

Price inKolkataRs. 7600
Price inPuneRs. 7600
Price inBangaloreRs. 7600
Price inHyderabadRs. 7600
Price inChennaiRs. 7600

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Test conducted by
Core Diagnostics Private Limited
ISO, CAP, NABL certified
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Contains 9 tests
Immunofixation Electrophoresis Serum
Immunoglobulin A
Immunoglobulin M
Beta 2 Microglobulin, Serum
Immunoglobulin G
Free Kappa
Free Lambda
Kappa/Lambda Ratio
Protein Electrophoresis, Serum