MPN Panel 3 near me in Guntur

Also referred as

Diagnostics and Prognostic panel for subtyping of Myeloproliferative Neoplasm

Myeloproliferative Neoplasm Panel

For men & women

Earliest reports in

360 hours

Contains

4 tests

Know more about this test

The MPN (Myeloproliferative Neoplasm) panel by PCR is a molecular diagnostic test that detects specific mutations associated with MPNs. This panel includes the analysis of BCR-ABL, JAK2 exon 12-14, CALR, and MPL mutations. The test utilizes PCR (Polymerase Chain Reaction) technology to amplify and identify these mutations in the patient's DNA. Detection of these mutations aids in the diagnosis, classification, and monitoring of MPNs, such as chronic myeloid leukemia (CML), polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF), enabling more accurate treatment decisions and patient management. This panel is widely available with Tata 1mg labs at an affordable price in Guntur.

Samples required

Blood

Find out

Why is this test booked?

Preparation for this test

Sample Collection

Who will collect your samples?

Understanding MPN Panel 3

Chronic myeloproliferative neoplasms (MPNs) are blood disorders in which the bone marrow produces too many red blood cells, white blood cells, or platelets. The {tet_name} is a comprehensive blood test used to evaluate genetic changes in blood cells that are characteristic of MPNs.

The MPN Panel Advanced detects key genetic mutations and fusions, including CALR, JAK2 (exons 12–15), MPL, and the BCR-ABL fusion. This helps doctors identify and classify different types of myeloproliferative neoplasms (MPNs), including both BCR-ABL1–positive and BCR-ABL1–negative conditions such as chronic myeloid leukemia (CML), polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF).

Doctors may recommend this panel if you experience symptoms such as fatigue, weakness, night sweats, or an enlarged spleen, or if you have abnormal blood counts. It is also advised for individuals with a family history of MPNs or known genetic risk factors. This test helps diagnose specific MPNs, differentiate between subtypes for appropriate treatment, monitor therapy response, and assess complication risks.

For this test, it is important to submit the clinical history, histopathology report, previous test results, and a doctor’s prescription at the time of sample collection. The Tata 1mg consolidated Test Requisition Form (TRF) must also be duly filled and submitted.

Lab test results may vary across different laboratories. Abnormal test results require an expert interpretation. Therefore, never try to self-medicate at home based solely on these results, and always consult a doctor for proper understanding of the test results.

What does MPN Panel 3 measure?

Contains 4 tests

The MPN Panel 3 detects important genetic mutations and gene fusions that help diagnose and classify myeloproliferative neoplasms (MPNs). This includes CALR mutations, JAK2 mutations (exons 12–15), MPL mutations, and the BCR-ABL1 fusion, which is essential for identifying chronic myeloid leukemia (CML). By analyzing these mutations and fusions, the test provides a comprehensive genetic profile, enabling doctors to accurately diagnose, classify, and manage both BCR-ABL1–positive and BCR-ABL1–negative MPNs.

Abnormal results may indicate the presence of specific MPNs: BCR-ABL1 fusion may suggest CML, JAK2 mutations may indicate polycythemia vera (PV) or essential thrombocythemia (ET), and CALR or MPL mutations may point to primary myelofibrosis (PMF). Further evaluation and consultation with a hematologist are necessary for accurate diagnosis and appropriate treatment.

CALR

JAK2 (12-15)

MPL

BCR-ABL Qualitative PCR

The BCR-ABL Qualitative PCR test checks a blood or bone marrow sample for the presence or absence of BCR-ABL mRNA transcripts, which are produced due to a chromosomal change called t(9;22), also known as the Philadelphia chromosome. If the test is positive, it can identify the specific transcript type, such as p210 (e13a2/e14a2) or p190 (e1a2), which helps doctors understand the type of leukemia and plan treatment accordingly.

Know more about BCR-ABL Qualitative PCR