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Written by
Dr. Shreya Gupta
BDS, MDS - Oral and Maxillofacial Pathology
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Dr. Ashish Ranjan
MBBS, MD (Pharmacology)
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BCR-ABL Qualitative PCR

Also known as Diagnostic marker for Chronic Myeloid Leukemia
42754500 5% Off
You need to provide
Blood
This test is for
Male, Female
Test Preparation
  1. No special preparation required
  2. Provide brief clinical history/ doctor's prescription at the time of sample collection

Understanding BCR-ABL Qualitative PCR


What is BCR-ABL Qualitative PCR?

This test detects the presence or absence of BCR-ABL mRNA transcript in the patient.

BCR-ABL is a fusion gene whose qualitative detection is done in bone marrow or peripheral blood samples. BCR-ABL is an activated protein kinase resulting translocation of long arms of chromosome 9 & chromosome 22 which is also known as Philadelphia chromosome. Philadelphia chromosome is found in both Chronic Myeloid Leukemia and Acute Lymphoid Leukemia. The BCR-ABL gene translocation or t(9;22) is found in more than 95% of CML patients, 5% of pediatric ALL-B CALLA positive, and 15-30% of adult ALL-B CALLA positive patients.

What is BCR-ABL Qualitative PCR used for?

This test is useful in diagnosing the presence of CML and ALL in an individual and also to monitor their treatment. The test must be ordered when signs and symptoms of leukemia such as anemia, weakness, palpitations, easy bruising and excessive bleeding due to loss of platelets, bone and joint pain, confusion and seizure, night sweats etc. are observed in the patient.


Interpreting BCR-ABL Qualitative PCR results


Interpretations

If the BCR-ABL sequence is present in the result of the Qualitative PCR test, it means that the person is diagnosed with positive CML and ALL.


BCR-ABL Qualitative PCR test price for other cities


Price inChennaiRs. 4275
Price inAllahabadRs. 4275
Price inGhaziabadRs. 4275
Price inBangaloreRs. 4275
Price inBhopalRs. 4275
+ more

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Test conducted by
Core Diagnostics Private Limited
ISO, CAP, NABL certified
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