
MPN Panel 3 near me in Asansol







The MPN (Myeloproliferative Neoplasm) panel by PCR is a molecular diagnostic test that detects specific mutations associated with MPNs. This panel includes the analysis of BCR-ABL, JAK2 exon 12-14, CALR, and MPL mutations. The test utilizes PCR (Polymerase Chain Reaction) technology to amplify and identify these mutations in the patient's DNA. Detection of these mutations aids in the diagnosis, classification, and monitoring of MPNs, such as chronic myeloid leukemia (CML), polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF), enabling more accurate treatment decisions and patient management. This panel is widely available with Tata 1mg labs at an affordable price in Asansol.








What does MPN Panel 3 measure?
Contains 4 testsThe MPN Panel 3 detects important genetic mutations and gene fusions that help diagnose and classify myeloproliferative neoplasms (MPNs). This includes CALR mutations, JAK2 mutations (exons 12–15), MPL mutations, and the BCR-ABL1 fusion, which is essential for identifying chronic myeloid leukemia (CML). By analyzing these mutations and fusions, the test provides a comprehensive genetic profile, enabling doctors to accurately diagnose, classify, and manage both BCR-ABL1–positive and BCR-ABL1–negative MPNs.
Abnormal results may indicate the presence of specific MPNs: BCR-ABL1 fusion may suggest CML, JAK2 mutations may indicate polycythemia vera (PV) or essential thrombocythemia (ET), and CALR or MPL mutations may point to primary myelofibrosis (PMF). Further evaluation and consultation with a hematologist are necessary for accurate diagnosis and appropriate treatment.
The BCR-ABL Qualitative PCR test checks a blood or bone marrow sample for the presence or absence of BCR-ABL mRNA transcripts, which are produced due to a chromosomal change called t(9;22), also known as the Philadelphia chromosome. If the test is positive, it can identify the specific transcript type, such as p210 (e13a2/e14a2) or p190 (e1a2), which helps doctors understand the type of leukemia and plan treatment accordingly.
Know more about BCR-ABL Qualitative PCR





- Fowlkes S, Murray C, Fulford A, De Gelder T, Siddiq N. Myeloproliferative neoplasms (MPNs) - Part 1: An overview of the diagnosis and treatment of the "classical" MPNs. Can Oncol Nurs J. 2018 Oct 1;28(4):262-268. [Accessed 14 Oct. 2025]. Available from:
- Rapado I, Grande S, Albizua E, Ayala R, Hernández JA, Gallardo M, Gilsanz F, Martinez-Lopez J. High resolution melting analysis for JAK2 Exon 14 and Exon 12 mutations: a diagnostic tool for myeloproliferative neoplasms. J Mol Diagn. 2009 Mar;11(2):155-61. [Accessed 14 Oct. 2025]. Available from:
- Thapa B, Fazal S, Parsi M, et al. Myeloproliferative Neoplasms. [Updated 2023 Aug 8]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from:
- Stock W, Yu D, Karrison T, Sher D, Stone RM, Larson RA, Bloomfield CD. Quantitative real-time RT-PCR monitoring of BCR-ABL in chronic myelogenous leukemia shows lack of agreement in blood and bone marrow samples. Int J Oncol. 2006 May;28(5):1099-103. PMID: 16596225. [Accessed 14 Oct. 2025]. Available From:
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