
Dehydroepiandrosterone









The Dehydroepiandrosterone is a blood test that helps evaluate the levels of a dehydroepiandrosterone (DHEA), a hormone produced by the adrenal glands, gonads and brain. This hormone plays an important role in developing male and female sexual characteristics and maintaining overall hormonal balance.












Understanding Dehydroepiandrosterone
DHEA changes to DHEA-S (DHEA-sulfate) in your adrenal glands and liver. Your body converts DHEAS into androgens (testosterone and androstenedione) and estrogen. Males make more testosterone, while females make more estrogen, but both the genders produce and use these hormones. DHEAS is critical for the development of male sexual characteristics during puberty and for reproduction in both the genders. DHEAS levels tend to peak around puberty and then naturally decline with age.
Your doctor may suggest a Dehydroepiandrosterone test along with other hormone tests if there are symptoms that may suggest an adrenal disorder, adrenal tumor or another problem. Also, it is often done for women who have signs and symptoms such as no menstrual periods and infertility and when a girl or woman has symptoms related to developing masculine physical characteristics. Infants or children with differences in sex development may also need a DHEAS test. Additionally, the test can be done when young boys show signs of precocious puberty.
Imbalances in DHEA levels can indicate various health problems, including adrenal dysfunction, hormonal imbalances, or conditions like Polycystic ovary syndrome (PCOS), Addison’s disease etc.
An overnight fasting is preferred for the Dehydroepiandrosterone test but is not mandatory. Inform your doctor about all the medications or supplements that you may be taking as these may affect your test results, potentially requiring adjustments or temporary discontinuation before this test.
Lab test results may vary across laboratories. The interpretation of the test results requires expert guidance. Therefore, don't self-medicate solely based on these results. Always consult the doctor to understand your test results correctly.
What does Dehydroepiandrosterone measure?
The Dehydroepiandrosterone test measures the concentration of dehydroepiandrosterone (DHEA) in the blood. This hormone is produced mainly by the adrenal glands, with smaller contributions from the ovaries in women and the testes in men. DHEA is vital for the development of secondary sexual characteristics during puberty and can be converted into more active androgens like testosterone and androstenedione, as well as into estrogens. DHEA levels can help doctors identify conditions like adrenal tumors, hirsutism, and other endocrine disorders, providing insights into hormonal balance within the body.





FAQs related to Dehydroepiandrosterone
- Dehydroepiandrosterone and Dehydroepiandrosterone Sulfate [Internet]. Rochester, NY: University of Rochester Medical Center; [Accessed 21 Oct. 2024]. Available from:
- Nagels HE, Rishworth JR, Siristatidis CS, Kroon B. Androgens (dehydroepiandrosterone or testosterone) for women undergoing assisted reproduction. Cochrane Database Syst Rev. 2015 Nov 26;2015(11):CD009749. [Accessed 21 Oct. 2024]. Available from:
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