Zusul 25mg Tablet

Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS

Last updated on 23 Jan 2026 | 05:35 PM (IST)

Zusul 25mg Tablet is used in the treatment of gastric problems like nausea, vomiting, heartburn, or indigestion. It also prevents acid reflux (acid going up to the food pipe) and hence helps in the treatment of gastroesophageal reflux disease (GERD).

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₹57.9 MRP ₹65.6312% off

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Zusul 25mg Tablet

strip of 10 tablets

₹57.9

~~₹65.63~~

Same composition

Lepivil 25mg Tablet

strip of 10 tablets

Levosulpiride (25mg)

by Leeford Healthcare Ltd

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General Information

Contains

Levosulpiride (25mg)

Marketer

Cucard Pharma

Storage

Store below 30°C

The content is shown in English

Product introduction

Zusul 25mg Tablet is taken by mouth with or without food. However, it is advisable to take it at the same time each day as this helps to maintain consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember.

Some common side effects of this medicine includes headache and fatigue. It also causes dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. You should immediately consult doctor if you have absence of periods, abnormal milk secretion, changes in sexual desire, or fever after taking this medicine.

Uses of Zusul Tablet

Benefits of Zusul Tablet

Heartburn
Heartburn is caused by stomach acid irritating the food pipe, leading to a burning sensation in the chest. Zusul 25mg Tablet helps improve stomach emptying and reduces acid-related discomfort, which helps relieve burning sensations and improves eating comfort.

Irritable bowel syndrome
Irritable bowel syndrome is a digestive condition that causes abdominal pain, bloating, and irregular bowel movements. Zusul 25mg Tablet helps improve gut movement and reduces discomfort, which can ease bloating, pain, and bowel irregularity, supporting better digestive comfort.

Gastroesophageal reflux disease (Acid reflux)
Acid reflux occurs when stomach contents flow back into the food pipe, causing irritation and discomfort. Zusul 25mg Tablet helps reduce reflux episodes by supporting proper stomach movement, which lowers acid backflow and improves long-term symptom control and quality of life.

Side effects of Zusul Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Zusul

Increased prolactin level in blood
Insomnia (difficulty in sleeping)
Sedation
Maculopapular rash
Extrapyramidal symptoms
Akathisia (inability to stay still)
Increased liver enzymes
Constipation
Weight gain

How to use Zusul Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zusul 25mg Tablet may be taken with or without food.

How Zusul Tablet works

Zusul 25mg Tablet is a atypical antipsychotic. It works by increasing the release of acetylcholine (a chemical messenger). This increases the movement of stomach and intestines, and prevents reflux (acid going up to the food pipe).

All substitutes for Zusul 25mg Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Take it as per dose and duration suggested by your doctor.
Zusul 25mg Tablet may cause dizziness. Do not drive or do anything that requires mental focus until you know how this medicine affects you.
Consult your doctor if you are pregnant, planning to become pregnant or breastfeeding.
Consult with your doctor immediately if you have absence if periods, abnormal milk secretion or changes in sexual desire, fever, muscle stiffness.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Zusul 25mg Tablet

Pregnancy

CONSULT YOUR DOCTOR

Zusul 25mg Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Zusul 25mg Tablet during breastfeeding is not available. Please consult your doctor.

Driving

UNSAFE

Zusul 25mg Tablet may cause side effects that could affect your ability to drive.
Zusul 25mg Tablet may cause drowsiness, numbness, or dyskinesias, therefore they should be advised to avoid driving and operations requiring supervision.

Kidney

CAUTION

Zusul 25mg Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

CAUTION

Zusul 25mg Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Zusul with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Moderate

Metoclopramide (Oral Route)

Talk to your doctor if you notice any unusual symptoms.

Moderate

Metoclopramide (Injection Route)

Talk to your doctor if you notice any unusual symptoms.

Frequently asked questions

What is Zusul 25mg Tablet used for?

Zusul 25mg Tablet is mainly used to treat gastric problems like nausea, vomiting, heartburn, or indigestion. This medicine may be used sometimes to manage mental health conditions like depression or schizophrenia, depending on the dose.

What are the serious side effects of Zusul 25mg Tablet?

Although rare, serious side effects of Zusul 25mg Tablet may include muscle stiffness or shaking, high fever (possible neuroleptic malignant syndrome), seizures, and abnormal heart rhythm. You should seek immediate help if you notice any of these symptoms.

Who should not take Zusul 25mg Tablet?

Individuals should not take Zusul 25mg Tablet if they are allergic to any ingredient present in Zusul 25mg Tablet, have epilepsy or seizures, have breast cancer or tumors dependent on prolactin, or have severe kidney or liver disease.

Can I drive while taking Zusul 25mg Tablet?

You should avoid driving or using heavy machines if you feel drowsy, dizzy, or restless after taking Zusul 25mg Tablet, especially during the first few days.

What precautions should I take while using Zusul 25mg Tablet?

While using Zusul 25mg Tablet, you should avoid alcohol, monitor for abnormal movements or hormone changes, take medicine at the same time daily, and do not stop suddenly without medical advice.

Can Zusul 25mg Tablet affect my hormones?

Yes. Zusul 25mg Tablet may raise prolactin levels, which can cause symptoms like missed periods, milk discharge, or enlarged breasts in both men and women.

Is levosulpiride safe?

Levosulpiride is safe if used at prescribed doses for the prescribed duration as advised by your doctor

Is levosulpiride an antidepressant?

No, it is used in the treatment of gastro-oesophageal reflux disease, irritable bowel syndrome, psychosis, dyspepsia

What is levosulpiride?

Levosulpiride belong to class of medication called as atypical antipsychotics. It acts by decreasing the activity of dopamine in the brain

What are its uses?

Levosulpiride is used in the treatment psychosis, depression, gastro-oesophageal reflux disease, irritable bowel syndrome and dyspepsia

Does levosulpiride cause erectile dysfunction?

No. patients should follow advice of the doctor regarding the possible side effects.

Can I take Zusul 25mg Tablet with omeprazole?

Zusul 25mg Tablet can be safely taken with omeprazole as no harmful effects have been reported clinically. A fixed-dose combination of these two medicines is also available. Zusul 25mg Tablet works by increasing the gut motility and Omeprazole decreases the acid production in the stomach. So, this combination is very effective in the treatment of reflux esophagitis associated with acidity, heartburn, intestinal and stomach ulcers.

Fact Box

Chemical Class

Benzamide derivative

Habit Forming

Therapeutic Class

NEURO CNS

Action Class

Atypical Antipsychotics

Related lab tests

Complete Blood Count

References

Lozano R, Concha MP, Montealegre A, et al. Effectiveness and safety of levosulpiride in the treatment of dysmotility-like functional dyspepsia. Ther Clin Risk Manag. 2007;3(1):149-55. [Accessed 23 Jan. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 25 Mar. 2019] (online) Available from:
Levosulpiride [Patient Information Leaflet]. Bangalore, India: Micro Labs Limited; 2022.

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Cucard Pharma
Address: CUBIT HOUSE, 13/369, Panchratna Estate, B/h Ankoor Oil Factory, Opp. Bhagyoday Hotel, Changodar, Ahmedabad-382210 (Guj.) INDIA.

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Provide right medicines

Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose

In accordance with the law

Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945

Zusul 25mg Tablet

Save more with additional offers

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Zusul Tablet

Benefits of Zusul Tablet

Side effects of Zusul Tablet

How to use Zusul Tablet

How Zusul Tablet works

All substitutes for Zusul 25mg Tablet

Lepivil 25mg Tablet

Lesuride Tablet

Levazeo 25 Tablet

Levogastrol Tablet

Neopride Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Metoclopramide (Oral Route)

Metoclopramide (Injection Route)

Frequently asked questions

What is Zusul 25mg Tablet used for?

What are the serious side effects of Zusul 25mg Tablet?

Who should not take Zusul 25mg Tablet?

Can I drive while taking Zusul 25mg Tablet?

What precautions should I take while using Zusul 25mg Tablet?

Can Zusul 25mg Tablet affect my hormones?

Is levosulpiride safe?

Is levosulpiride an antidepressant?

What is levosulpiride?

What are its uses?

Does levosulpiride cause erectile dysfunction?

Can I take Zusul 25mg Tablet with omeprazole?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Complete Blood Count

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests