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Levosulpiride

Written By Dr. MayankReviewed By Dr. Rajeev Sharma
Last updated 25 Nov 2025 | 09:34 AM (UTC)

Levosulpiride Uses

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How Levosulpiride works

Levosulpiride is a atypical antipsychotic. It works by increasing the release of acetylcholine (a chemical messenger). This increases the movement of stomach and intestines, and prevents reflux (acid going up to the food pipe).

Common side effects of Levosulpiride

Increased prolactin level in blood, Insomnia (difficulty in sleeping), Sedation, Maculopapular rash, Extrapyramidal symptoms, Weight gain, Akathisia (inability to stay still), Increased liver enzymes, Constipation
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Expert advice for Levosulpiride

  • Take it as per dose and duration suggested by your doctor.
  • Levosulpiride may cause dizziness. Do not drive or do anything that requires mental focus until you know how this medicine affects you.
  • Consult your doctor if you are pregnant, planning to become pregnant or breastfeeding.
  • Consult with your doctor immediately if you have absence if periods, abnormal milk secretion or changes in sexual desire, fever, muscle stiffness.

Frequently asked questions for Levosulpiride

Levosulpiride is safe if used at prescribed doses for the prescribed duration as advised by your doctor
No, it is used in the treatment of gastro-oesophageal reflux disease, irritable bowel syndrome, psychosis, dyspepsia
Levosulpiride belong to class of medication called as atypical antipsychotics. It acts by decreasing the activity of dopamine in the brain
Levosulpiride is used in the treatment psychosis, depression, gastro-oesophageal reflux disease, irritable bowel syndrome and dyspepsia
No. patients should follow advice of the doctor regarding the possible side effects.
Levosulpiride can be safely taken with omeprazole as no harmful effects have been reported clinically. A fixed-dose combination of these two medicines is also available. Levosulpiride works by increasing the gut motility and Omeprazole decreases the acid production in the stomach. So, this combination is very effective in the treatment of reflux esophagitis associated with acidity, heartburn, intestinal and stomach ulcers.