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Zoflo-O Plus Tablet is a combination medicine used in the treatment of diarrhea and dysentery. It relieves the symptoms of diarrhea such as stomach pain, cramps, and loose stools. It also kills diarrhea-causing microorganisms and promotes the growth of good bacteria.

Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 25 Nov 2025 | 03:07 PM (IST)
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General Information

Contains

Lactobacillus (120Million spores)+ Ofloxacin (200mg)+ Ornidazole (500mg)+ Saccharomyces boulardii (2Million spores)

Marketer

Allenge India

Storage

Store below 30°C
The content is shown in English
Zoflo-O Plus Tablet image
Zoflo-O Plus Tablet image

Product introduction

Zoflo-O Plus Tablet is taken with food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine.

The most common side effects are headache, nausea, vomiting, stomach pain, bloating, loss of appetite, and skin rash. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. This medicine may also cause dizziness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your dizziness. Lifestyle modifications like having fiber rich diet, increase fluid intake and regular exercise can help you to get better results.

Before taking this medicine, you should tell your doctor if you are pregnant, planning pregnancy or breastfeeding. You should also tell your doctor if you have any liver diseases so that your doctor can prescribe a suitable dose for you.

Uses of Zoflo-O Plus Tablet

Benefits of Zoflo-O Plus Tablet

Diarrhea
Diarrhea is an increase in the frequency of bowel movements or loose watery bowel movements. It can most commonly occur due to an infection of the digestive tract. Zoflo-O Plus Tablet helps to treat diarrhea that is caused due to bacteria or parasitic worm infections. Zoflo-O Plus Tablet also contains beneficial bacteria that protect the inner layers of your stomach and intestines. This medicine can relieve frequent loose motions and also help you to stay well by preventing them from coming back. You need to take this medicine regularly to get the most out of it and you should drink plenty of fluids while taking it to make sure you stay hydrated.
Dysentery
Dysentery or amoebic dysentery is a parasitic infection of the intestines that occurs mostly due to intake of contaminated food or water. The symptoms include loose stools (diarrhea), stomach cramps and stomach pain. Zoflo-O Plus Tablet helps to treat this infection by killing the infection causing parasites. It relieves these symptoms and also helps you to stay well by preventing them from coming back. You need to take this medicine regularly to get the most out of it and you should drink plenty of fluids while taking it to make sure you stay hydrated.

Side effects of Zoflo-O Plus Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Zoflo-O Plus
  • Nausea
  • Vomiting
  • Bloating
  • Stomach pain
  • Loss of appetite
  • Dizziness
  • Headache

How to use Zoflo-O Plus Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zoflo-O Plus Tablet should be taken with or after food.

How Zoflo-O Plus Tablet works

Zoflo-O Plus Tablet is a combination of four medicines: Lactobacillus, Ofloxacin, Ornidazole and Saccharomyces boulardii. Ofloxacin is an antibiotic. It kills bacteria by preventing them from reproducing and repairing themselves. Ornidazole is also an antibiotic which kills the bacteria and other microorganisms by damaging the DNA. Together, they treat your infection effectively. Lactobacillus and Saccharomyces boulardii are live microorganisms which restore the balance of good bacteria in the intestine that may get upset with antibiotic use or due to intestinal infections.

All substitutes for Zoflo-O Plus Tablet

For information purposes only. Consult a doctor before taking any medicine.

Get IT Plus Tablet

by Lifeline Remedies India Pvt Ltd
₹9.31/tablet
14% costlier
<h3 class=bodySemiBold>Get IT Plus Tablet</h3>

Quick tips

  • You have been prescribed Zoflo-O Plus Tablet for the treatment of diarrhea and dysentery.
  • Take it at least 2 hours after taking other medicines, as it may interfere with the absorption of other medicines.
  • Diarrhea can cause water loss and electrolyte imbalance. Drink plenty of fluids especially ORS (oral rehydration solution) to help keep you hydrated.
  • Consult your doctor if your symptoms last for more than 48 hours.
  • Do not use Zoflo-O Plus Tablet if you have blood in your stool or if you are severely constipated.

Safety advice

Alcohol

Alcohol

UNSAFE
It is unsafe to consume alcohol with Zoflo-O Plus Tablet
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Zoflo-O Plus Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Zoflo-O Plus Tablet during breastfeeding is not available. Please consult your doctor.
Driving

Driving

UNSAFE
Zoflo-O Plus Tablet may cause side effects that could affect your ability to drive.
Kidney

Kidney

SAFE IF PRESCRIBED
Zoflo-O Plus Tablet is probably safe to use in patients with kidney disease. Limited data suggest dose adjustment may not be needed.
Liver

Liver

CAUTION
Zoflo-O Plus Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.

Frequently asked questions

Take Zoflo-O Plus Tablet as soon you as remember it. However, do not take it if it's almost time for your next dose. Also, do not take an extra dose to make up for your missed dose.
No, do not stop taking Zoflo-O Plus Tablet and complete the full course of treatment even if you feel better. Your symptoms may improve before the infection is completely cured.

Fact Box

Habit Forming

No

Therapeutic Class

GASTRO INTESTINAL

Related lab tests

Stool Examination R/M

References

  1. ScienceDirect. Lactobacillus. [Accessed 15 Apr. 2019] (online) Available from:
  2. Ofloxacin. Raritan, New Jersey: Ortho-McNeil-Janssen Pharmaceuticals, Inc.; 2008. [Accessed 01 Apr. 2019] (online) Available from:
  3. ScienceDirect. Ornidazole. [Accessed 15 Apr. 2019] (online) Available from:
  4. ScienceDirect. Saccharomyces Boulardii. [Accessed 15 Apr. 2019] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Allenge India
Address: Plot No. 249, Daksh House, Industrial Area Phase -II, Panchkula -134109 (Haryana) India

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Zoflo-O Plus Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's â„ž and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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