Medicine Overview of Zigarab Tablet
Side Effects of Zigarab are Vomiting, Headache, Stomach pain, Nausea, Flatulence, Diarrhoea.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zigarab 20 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Zigarab 20 mg Tablet is a proton pump inhibitor (PPI). It works by reducing the amount of acid in the stomach which helps in relief of acid related indigestion and heartburn.
In Depth Information on Zigarab Tablet
- Inform your doctor if you get watery diarrhea, fever, or stomach pain that does not go away.
- Inform your doctor if you do not feel better after taking it for 14 days as you may be suffering from some other problem that needs attention.
- Long-term use can cause weak bones and deficiency of minerals such as magnesium. Take adequate dietary intake of calcium and magnesium or their supplements as prescribed by your doctor.
- You have been prescribed Zigarab 20 mg Tablet to reduce stomach acid and heal stomach ulcers.
- Take it one hour before the meal, preferably in the morning.
- It is a well-tolerated medicine and provides relief for a long time.
Zigarab Tablet related warnings
WEIGH RISKS VS BENEFITS
Zigarab 20 mg Tablet may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Zigarab 20 mg Tablet is probably unsafe to use during lactation.
Limited human data suggest that the drug could represent a significant risk to the baby.
Zigarab 20 mg Tablet may make you feel dizzy, sleepy, tired, or decrease alertness. If this happens, do not drive.
Zigarab 20 mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Zigarab 20 mg Tablet is recommended.
Zigarab 20 mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Zigarab 20 mg Tablet may be needed. Please consult your doctor.
If you miss a dose of Zigarab 20 mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Frequently asked questions about Zigarab Tablet
Q. Is Zigarab an over the counter product?
No, Zigarab is not an over the counter product, it is available when prescribed by a doctor.
Q. Is Zigarab an antacid?
Zigarab is not an antacid. It belongs to the class of proton pump inhibitors (PPIs) which decrease the amount of acid produced in the stomach while antacids only neutralize the stomach acid by coating the stomach.
Q. Does Zigarab cause osteoporosis (thinning of bones)?
Yes, long term use of Zigarab can cause osteoporosis (thinning of bones). It decreases the calcium absorption leading to calcium deficiency and increases the risk of bone fractures of hip, wrist or spine. Inform your doctor if you have osteoporosis or if you are taking corticosteroids (these can increase the risk of osteoporosis) before starting your therapy. Take enough calcium and vitamin D to reduce the risk.
Q. Can I take aluminum hydroxide and magnesium carbonate or other antacids with Zigarab?
Zigarab can be taken with antacids like aluminum hydroxide, magnesium carbonate or sodium bicarbonate. Zigarab takes a few days to show its effect, so antacids can be taken during that time for relief of acidity and heartburn. However, antacids should be taken two hours before or one hour after taking Zigarab as antacids can increase the pH of the stomach and decrease the action of Zigarab which requires a lower pH for its action.
Q. Does Zigarab have addictive potential?
No, Zigarab has no addictive potential. It shows no withdrawal symptoms when you stop using this medicine.
Yes, Zigarab is safe if taken for prescribed duration in prescribed doses as advised by your doctor. However, there are some very common side effects that you can experience at effective doses like nausea, abdominal pain, constipation, diarrhea, and flatulence.
Q. Does Zigarab cause hair loss?
No, hair loss has not been reported as a side effect of Zigarab. Talk to your doctor in case there is excessive hair fall as it could be due to some underlying problem that needs attention.
Q. Does Zigarab cause flatulence (gas or bloating)?
Flatulence (gas) has been reported as a common side effect of Zigarab. Although it would be mild to moderate in nature and transient.
Q. Does Zigarab cause tinnitus (ringing in the ears)?
Tinnitus (ringing sensation in the ears) has not been seen as a side effect with the use of Zigarab. Talk to your doctor in case you have this problem as it could be due to some underlying condition that needs attention.
Q. Does Zigarab cause weight gain?
Weight gain has been reported as a rare side effect of Zigarab. Weight gain can add to your problem of acidity and heartburn. So, you must try to do some exercise and make healthy changes in your diet to control your weight.
Yes, like any other medicine, Zigarab also expires. Always check the expiry date on the pack of the medicine before using it.
Q. Does Zigarab cause constipation?
Constipation is a common side effect seen in patients using Zigarab. Making healthy lifestyle changes like doing yoga, taking high fiber diet and plenty of fluids will prevent constipation.
Q. Does Zigarab cause high blood pressure?
Zigarab is not reported to cause high blood pressure. In case you experience high blood pressure, talk to your doctor as it may need attention. Common side effects seen with Zigarab includes nausea, abdominal pain, constipation, diarrhea, and flatulence.
Q. Does Zigarab cause headache?
Headache is reported as one of the common side effects of Zigarab. Please consult your doctor in case you experience an intolerable headache for a prolonged duration while taking Zigarab.
Q. Can I take Zigarab with ranitidine?
Yes, Zigarab can be taken with ranitidine. As Zigarab show its effect after some days, Ranitidine can be taken for immediate relief. No drug-drug interactions or change in side effect profile has been reported when they are used together compared to either drug alone.
Q. Can I take Zigarab with ibuprofen?
Zigarab can be taken with ibuprofen. Zigarab is used to prevent painkiller (NSAIDs) induced gastritis and stomach ulcers by decreasing the production of acid in the stomach. There are no reported drug interactions or harmful effects when they are used together.
Q. Can I take Zigarab with paracetamol?
Zigarab can be taken with paracetamol. Zigarab is used to prevent painkiller (NSAIDs) induced stomach ulcers by decreasing the production of acid in the stomach. There are no reported drug interactions or harmful effects when they are used together.
Q. How is Zigarab metabolized?
Zigarab is metabolized in the liver mainly by microsomal CYP450 enzymes (CYP2C19 and CYP3A4). Patients with poor CYP2C19 enzymatic activity will have higher levels of Zigarab for a long time and a better suppression of stomach acid.
Q. Can Zigarab be used for the treatment of throat infection?
No, Zigarab is not meant for throat infections. However, it may be given along with antibiotics and other drugs to protect the stomach from excessive acid secretion.
Q. Why is Zigarab used with cinitapride for some conditions?
Cinitapride increases the movement of the gut and is useful in the treatment of conditions like heartburn, dyspepsia and is also useful in the treatment of reflux esophagitis. It has much better efficacy when it is used with Zigarab.
Q. Does Zigarab play any role in treating ulcerative colitis?
Zigarab does not have any role in the treatment of ulcerative colitis. However, it can be given if there is associated dyspepsia or increased stomach acid secretion. Talk to your doctor before taking any treatment for ulcerative colitis.
Q. Can Zigarab be used for reflux esophagitis?
Yes, Zigarab is effective in the treatment of reflux esophagitis. It is a disease in which stomach acid or bile irritates and inflames the lining of the food pipe. Zigarab decreases the production of acid in the stomach and can help in healing the inflamed and eroded esophagus.The efficacy is better when it is given in combination with a prokinetic agent like domperidone.
Q. Is Zigarab being used for treating weight loss?
No, Zigarab is not used for the treatment of weight loss. It is a proton pump inhibitor and is used for the treatment of acidity, heartburn, intestinal ulcers and stomach ulcers.
Q. Is there any role of Zigarab in treating hiatus hernia?
A hiatus hernia is the bulging of the stomach into the chest through an esophageal opening in the diaphragm which is larger than the normal size. A hiatus hernia is associated with acidity and heartburn. Zigarab does not play any role in treating hiatus hernia, however, it can help in relieving the symptoms of acidity, heartburn and acid reflux.
Q. Can I take Zigarab with vitamin D?
Yes, vitamin D can be taken with Zigarab. Vitamin D is generally advised to be taken as a supplement with Zigarab as its long-term use decreases the absorption of calcium and cause calcium deficiency. This can lead to osteoporosis (thinning of bones) and increase the risk of bone fractures like hip, wrist and spine fractures.
Q. How is Zigarab useful in the treatment of H. pylori?
Zigarab is used along with antibiotics for the treatment of H.Pylori infection. It works by decreasing stomach acid volume and decreasing breakdown and washout of antibiotics leading to an increased antibiotic concentration and tissue penetration. It also helps in the symptomatic relief by decreasing associated acidity, reflux, and heartburn.
Q. Can I take Zigarab with domperidone?
Zigarab can be safely taken with domperidone as no harmful effects have been reported clinically. A fixed-dose combination of these two medicines is also available. Domperidone increases gut motility and Rabeprazole decreases the acid production in the stomach. So, this combination is very effective in the treatment of reflux esophagitis associated with acidity, heartburn, intestinal and stomach ulcers.
Q. Can long term use of Zigarab cause magnesium deficiency?
Long-term use of Zigarab can lower magnesium levels in patients taking multiple daily doses for a year or longer (at least 3 months). Get your magnesium levels checked at regular intervals. Tell your doctor if you experience seizures, dizziness, abnormal or fast heartbeat, jitteriness, jerking movements or shaking (tremors), muscle weakness, spasms of the hands and feet, cramps, muscle aches or spasm of the voice box.
Severely interacts with other drugs like
Taking Zigarab with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Medicines with composition Indinavir: Indivan
Medicines with composition Cilostazol: Pencil, Zilast, Stozic, Preclaud, Pletoz
Medicines with composition Ritonavir: Viriton, Ritomune, Ritomax
Medicines with composition Nelfinavir: Nel
Medicines with composition Chlordiazepoxide: Equblam, Zepox, Raipox, Equiliser, Anxibrium, Cdcon, Czep, Poxid, Peaceoxide, Anxon H
Medicines with composition Sodium Bicarbonate: Sodamax, Sobinix, Sobimed, Soda Bicarb Glycerin
Medicines with composition Clobazam: Risure, Boze, Clobazed, Solzam, Clozop, Sloba, Clobakon, Closum, Emilep, Oresta
Medicines with composition Flurazepam: Nindral
Medicines with composition Etizolam: Etizom, Etimax, Etezole, Etilax, Ruhiz, Zoly, Etizaa, Etirest, Etimark, Etizep
Medicines with composition Magnesium Hydroxide: Mgmax
Medicines with composition Clonazepam: Panik, Klojet, Sezolan, Brispam, Naze, Clono, Sonazep, Closis, Ubitpam, Clonarey
Medicines with composition Lorazepam: Psycopan, Urpam, Anxionil, Biokalm, Larosh, Loripam, Loratranc, Lori, Loralite, Loranxit
Medicines with composition Diazepam: Dizapam, Zeopse, Karpam, Osopose, Campin, Elpam, Elpose, Calmtack, Peptica, Placidox
Medicines with composition Midazolam: Medzol, Mezolam, Midfast
Medicines with composition Nitrazepam: Konit, Zipam, Enzed, Nitrosh, Hypnonex, Nitram, Nit, Nap, Nitrac, Nitrapam
Medicines with composition Alprazolam: Eurolam, Tenzo, Indolam, Alzopam, Ezoprax, Aryalam, Lamad, Nucalm, Altok, Sozox
Medicines with composition Methotrexate: Methosis, Metrex, Cytotrex, Rhutrex, Meditrex, Vibzi, Meth
Medicines with composition Phenytoin: Stoin, Marantin, Notian, Phenytoin Sodium, Phenozed, Episol, Epidium, Epilog, Neptoin, C-Toin
Medicines with composition Dipyridamole: Cardiwell
Medicines with composition Erythromycin: Arthrox, Ciresto, Eromax, Avithrocin, Denthrocin, E Cin, T Mycin, Suzithrocin, Methro, Erypsin
Medicines with composition Spiramycin: Spiramycin, Macromycin, Spiratox
Medicines with composition Clopidogrel: Clopinorm, Hanatrel, Clopido, Klopy, Flo, Clopizen, Clopilet, Clopifine, Clopace, MYO
Medicines with composition Roxithromycin: Zuroxy, Roxilim, Rox Thro, Ani Rox, Enirox, Serox, Marox, Roxup, Roxiden, P Rox
Medicines with composition Clarithromycin: Clarimac, CLR, Claripax, O Clar, Clarinic, C Cin, Klarim, Klarinton, Cloff, Clavid
Medicines with composition Digoxin: Cardisip, Digon, Cardioxin
One of the following vendor pharmacies will deliver Zigarab 20mg Tablet: DPP, ZEL, HAT, BIO, VTR, BBN, BHS, SVH, RTL, KNH, MSD, BBS, BNT, DAO, RHL, DYG, AVS, VHP, MAX, ALY, LHA, KIM, RSS, UHP, AFT, RAC, KHH, PRT, HMP, JBT, STA, SGH, AXM, HLT, WDE, MKT, CMC, GDA, WSI, SCP, NLP, SHD, HBV, RPI, EEC, RKS, ADT, PPR, HGI, LMS, SHC, SPD, MIP, CPK, STS, VSL, SBA, SSI, NAS, WAD, ANP, SAF, CMD, HZF, PSF, VSC, INC, 1MH, GHR, IAD, GNC, NDP, VOP, PVP, DLY, IPP, SWP, ANT, PNT, UPA, NTL, DGN, HWS, GTC, AAY, PHC, BAL, MKS, HCP, SGC, AYN, BHA, HSP, BLE, SSS, BJR, OLT, SNH, XMX, AMR, DRA, CRN, BLS, EPS, HIP, PRL, DYL, THP, NVL, 9MM, EAN, AYM, BTM, PHN, OWP, RHW, BNC, MBP, BSN, APS, BJP, ARD, HPC, GMA, ATP, ABP, JVO, MJT, SBN, BGS, GFL, AMH, MLC, SMS, PEN, MPC, CLT, MDO, SDE, RVC, TRP, SDM, MDH, RRP, NXG, WHL, TAT, SWA, PTI, SAA, EMB, DLP, PNQ, FGH, AYU, HPP, FRM, UBR, FIP, HTS, RDH, MAM, BAP, KLC, PWN, QLF, VJS, SPF, DPL, PRN, PTP, USF, JSL, ANS, HEX, JVN, SBL, VDH, NWP, UVD, JIV, RHS, MAP, SVS, GBL, TOM, KMC, NPH, IPL, PMA, BDI, JJE, GLM, 4IT, EVP, JHC, RPP, AVB, OWN, RDR, TSS, KIS, PRC, EQN, BHM, ASP, SNG, BHP, AAR, TNH, OMV, ESY, KHD, PLT, ENP, HSM, BRC, SJP, RUS, VNS, RSA, SLN, WPL, IMC, ATL, SIO, NEO, RWP, ALC, SCH, ZVP, AHP, DHR, SLC, DZY, OHM, NNP, NTB, AVL, SHG, RGH, GEO, LHP, KHC, TFP, ZPR, NLG, BLP, YMI, NVY, OIP, SRG, LCC, BNA, VRS, QTM, BMJ, AGT, MAK, GLD, OBS, SMN, DVH, MRS, UMP, GGL, DHP, SHN, DFP, GPP, NSL, HNP, WHP