Zextra 600mg Tablet

Tolmetin (600mg)

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Zextra 600mg Tablet is a pain-relieving medicine. It effectively alleviates pain and inflammation in conditions like rheumatoid arthritis and osteoarthritis.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 21 Jul 2026 | 01:03 AM (IST)

₹173 MRP ₹187.58% off

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Amtoril 600mg Tablet

₹167~~₹181.22~~

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Zextra 600mg Tablet

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₹173

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Same composition

Amtoril 600mg Tablet

strip of 6 tablets

Tolmetin (600mg)

by Macleods Pharmaceuticals Pvt Ltd

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General Information

Contains

Tolmetin (600mg)

Marketer

Dr Reddy's Laboratories Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Zextra 600mg Tablet is best taken with food. This will prevent you from getting an upset stomach. Take it regularly and at the same time each day. This will increase the effectiveness of the medicine. It is important to keep taking the medicine until your doctor tells you it is safe to stop.

Vomiting, stomach pain, nausea, and indigestion are some of the common side effects that might be observed in taking this medicine. It may also cause dizziness, drowsiness, or visual disturbances. Do not drive or operate heavy machines until you are fine. Your doctor may regularly monitor your kidney function, liver function, and levels of blood components if you are taking the medicine for long-term treatment. Long-term use may lead to serious complications such as stomach bleeding and kidney problems.

Uses of Zextra Tablet

Pain relief

Benefits of Zextra Tablet

Pain relief
Zextra 600mg Tablet belongs to a group of medicines called nonsteroidal anti-inflammatory drugs (NSAIDs). It is used to relieve pain, inflammation, and swelling in painful conditions that affect joints and muscles. It works by blocking chemical messengers in the brain that tell us we have pain. It can help relieve pain in conditions like rheumatoid arthritis and osteoarthritis.

Take it as it is prescribed to get the most benefit. Do not take more or for longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time. This will help you to go about your daily activities more easily and have a better, more active, quality of life. Mild symptoms of osteoarthritis can sometimes be managed by simple measures such as regular exercise, losing weight, good posture, and wearing suitable footwear.

Side effects of Zextra Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Zextra

Vomiting
Nausea
Stomach pain/epigastric pain
Indigestion
Dizziness
Drowsiness
Visual disturbance

How to use Zextra Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zextra 600mg Tablet should be taken with or after food.

How Zextra Tablet works

Zextra 600mg Tablet is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the release of certain chemical messengers that cause pain and inflammation (redness and swelling).

All substitutes for Zextra 600mg Tablet

For information purposes only. Consult a doctor before taking any medicine.

Amtoril 600mg Tablet

by Macleods Pharmaceuticals Pvt Ltd

₹27.83/tablet

141% costlier

Quick tips

You have been prescribed Zextra 600mg Tablet to relieve pain and inflammation.
Take it with food or milk to prevent upset stomach.
Take it as per the dose and duration prescribed by your doctor. Long term use may lead to serious complications such as stomach bleeding and kidney problems.
It may cause dizziness, drowsiness or visual disturbances. Use caution while driving or doing anything that requires concentration.
Avoid consuming alcohol while taking Zextra 600mg Tablet as it can cause excessive drowsiness and increase your risk of stomach problems.
Inform your doctor if you have a history of heart disease or stroke.
Your doctor may regularly monitor your kidney function, liver function and levels of blood components, if you are taking this medicine for long-term treatment.

Safety advice

Alcohol

CAUTION

Alcohol should be used with caution while taking Zextra 600mg Tablet.

Pregnancy

CONSULT YOUR DOCTOR

Zextra 600mg Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

SAFE IF PRESCRIBED

Available human data suggest that the drug does not pass into breast milk in clinically significant amounts and is unlikely to harm the infant.

Driving

UNSAFE

Zextra 600mg Tablet may cause side effects that could affect your ability to drive.

Kidney

CAUTION

Zextra 600mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Use of Zextra 600mg Tablet is not recommended in patients with severe kidney disease.

Liver

CAUTION

Zextra 600mg Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
Inform your doctor if you develop symptoms of liver disease like jaundice while taking this medicine.

Interaction with drugs

Taking Zextra with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Tacrolimus (Oral Route)

If concurrent use is essential, your doctor may monitor your tacrolimus levels, potassium levels and kidney function closely. They may adjust the doses as per the observations.

Severe

Methotrexate (Injection Route)

Please consult with your doctor. Doctor may monitor liver function and blood cell counts.

Severe

Methotrexate (Injection Route)

Please consult with your doctor. Doctor may monitor liver function and blood cell counts.

Severe

Methotrexate (Injection Route)

Please consult with your doctor. Doctor may monitor liver function and blood cell counts.

Severe

Methotrexate (Injection Route)

Please consult with your doctor. Doctor may monitor liver function and blood cell counts.

Frequently asked questions

What is Zextra 600mg Tablet sodium?

Zextra 600mg Tablet sodium is a drug belonging to the class non-steroidal anti-inflammatory drugs (NSAIDs). It acts by stopping the production of chemicals (prostaglandin, histamine, etc.) that cause pain, redness and swelling of joints

What is Zextra 600mg Tablet sodium is used for?

Zextra 600mg Tablet is used to relieve pain, tenderness, swelling, and stiffness caused by osteoarthritis, rheumatoid arthritis and juvenile rheumatoid arthritis

Is Zextra 600mg Tablet a narcotic drug?

No, patients should follow the advice of the doctor regarding its use.

Fact Box

Chemical Class

Aryl- phenyl ketones

Habit Forming

Therapeutic Class

PAIN ANALGESICS

Action Class

NSAID's- Non-Selective COX 1&2 Inhibitors (acetic acid)

References

Furst DE, Ulrich RW, Varkey-Altamirano C. Nonsteroidal Anti-Inflammatory Drugs, Disease Modifying Antirheumatic Drugs, Nonopioids Analgesics, & Drugs Used in Gout. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 628.
Grosser T, Smyth E, FitzGerald GA. Anti-Inflammatory, Antipyretic, and Analgesic Agents; Pharmacotherapy of Gout. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 986.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1378.
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 02 Apr. 2019] (online) Available from:

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Musculo-skeletal pain

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Dr Reddy's Laboratories Ltd
Address: Dr. Reddy's Laboratories Ltd., Village Malpur, P.O.Bhud, Baddi, Dist. Solan, H.P.

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Home

Pain Analgesics

Anti Rheumatics Non Steroidal Systemic

Zextra 600mg Tablet

Zextra 600mg Tablet

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Zextra Tablet

Benefits of Zextra Tablet

Side effects of Zextra Tablet

How to use Zextra Tablet

How Zextra Tablet works

All substitutes for Zextra 600mg Tablet

Amtoril 600mg Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Tacrolimus (Oral Route)

Methotrexate (Injection Route)

Methotrexate (Injection Route)

Methotrexate (Injection Route)

Methotrexate (Injection Route)

Frequently asked questions

What is Zextra 600mg Tablet sodium?

What is Zextra 600mg Tablet sodium is used for?

Is Zextra 600mg Tablet a narcotic drug?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

User feedback

What are you using Zextra Tablet for?

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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