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Zerofen 100mg Tablet

Ketoprofen (100mg)
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Zerofen 100mg Tablet is a pain-relieving medicine. It is used to treat conditions such as painful flare-ups of rheumatism, arthritis, strained muscles and tendons, and gout. It also used to treat other painful conditions of the bone or muscle and pain and inflammation following orthopedic surgery.

Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 25 Nov 2025 | 03:05 PM (IST)
₹50.9 MRP ₹56.2510% off 
 
 
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General Information

The content is shown in English
Zerofen 100mg Tablet image
Zerofen 100mg Tablet image

Product introduction

Zerofen 100mg Tablet should be taken with food to avoid stomach upset and reduce side effects. In general, you should try to use the smallest amount necessary to control your symptoms, for the shortest possible time. You should take this medicine regularly while you need it. Try not to miss doses as it will become less effective if you do.

The common side effects of this medicine include vomiting, stomach pain, nausea, and indigestion. If any of these side effects do not resolve with time or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms.

This medicine is generally considered safe but is not suitable for everybody. Before you take it, you should tell your doctor if you have kidney problems, asthma, blood disorders, or drink a lot of alcohol. Also, tell your doctor what other medicines you are taking to make sure you are safe. It is best to avoid drinking alcohol while using this medicine.

Uses of Zerofen Tablet

Benefits of Zerofen Tablet

Pain relief
Zerofen 100mg Tablet is a common painkiller used to treat aches and pains. It blocks chemical messengers in the brain that tell us we have pain. It is effective in relieving pain caused by arthritis and muscle aches. This medicine is very widely used and very rarely causes side effects if taken at the right dosage.
Take it as it is prescribed to get the most benefit. Do not take more or for longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time. This will help you to go about your daily activities more easily and have a better, more active, quality of life.

Side effects of Zerofen Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Zerofen
  • Vomiting
  • Nausea
  • Indigestion
  • Stomach pain

How to use Zerofen Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zerofen 100mg Tablet should be taken with or after food.

How Zerofen Tablet works

Zerofen 100mg Tablet is a non-steroidal anti-inflammatory drug (NSAIDs). It works by blocking the release of certain chemical messengers that cause fever, pain and inflammation (redness and swelling).

Quick tips

  • You have been prescribed Zerofen 100mg Tablet to relieve pain and inflammation.
  • Take it with food or milk to prevent upset stomach.
  • Take it as per the dose and duration prescribed by your doctor. Long term use may lead to serious complications such as stomach bleeding and kidney problems.
  • Do not take indigestion remedies (antacids) within two hours of taking Zerofen 100mg Tablet.
  • Avoid consuming alcohol while taking Zerofen 100mg Tablet as it can increase your risk of stomach problems.
  • Inform your doctor if you have a history of heart disease or stroke.
  • Your doctor may regularly monitor your kidney function, liver function and levels of blood components if you are taking this medicine for long-term treatment.

Safety advice

Alcohol

Alcohol

UNSAFE
It is unsafe to consume alcohol with Zerofen 100mg Tablet
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Zerofen 100mg Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

SAFE IF PRESCRIBED
Zerofen 100mg Tablet may be safe to use during breastfeeding. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Driving

Driving

UNSAFE
Zerofen 100mg Tablet may cause side effects that could affect your ability to drive.
You may feel sleepy, dizzy, faint, your eyesight may be affected or you may have a fit while taking Zerofen 100mg Tablet and this may affect your ability to drive.
Kidney

Kidney

CAUTION
Zerofen 100mg Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Regular monitoring of kidney function test is advised while you are taking this medicine. Use of Zerofen 100mg Tablet is not recommended in patients with severe kidney disease.
Liver

Liver

CONSULT YOUR DOCTOR
There is limited data available on the use of Zerofen 100mg Tablet in patients with liver disease.

Interaction with drugs

Taking Zerofen with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Tacrolimus (Oral Route)

If concurrent use is essential, your doctor may monitor your tacrolimus levels, potassium levels and kidney function closely. They may adjust the doses as per the observations.
Severe

Methotrexate (Injection Route)

Please consult with your doctor. Doctor may monitor liver function and blood cell counts.
Severe

Methotrexate (Injection Route)

Please consult with your doctor. Doctor may monitor liver function and blood cell counts.
Severe

Methotrexate (Injection Route)

Please consult with your doctor. Doctor may monitor liver function and blood cell counts.
Severe

Methotrexate (Injection Route)

Please consult with your doctor. Doctor may monitor liver function and blood cell counts.

Frequently asked questions

In a few cases, Zerofen 100mg Tablet may cause an increase in blood pressure. Before taking Zerofen 100mg Tablet, you should inform your doctor if you have high blood pressure. Also, inform your doctor about the medicines that you might be taking for it. Doctors prescribe this medicine to people with high blood pressure only if the benefits outweigh the risks. In fact, patients with uncontrolled blood pressure should be very careful and should regularly monitor their blood pressure while on Zerofen 100mg Tablet.
Taking Zerofen 100mg Tablet on an empty stomach may cause nausea, vomiting, upset stomach, burning sensation in food pipe, and stomach pain. Therefore, Zerofen 100mg Tablet should be taken with a glass of water either with meals or just after meals. Your doctor may also recommend taking an antacid with Zerofen 100mg Tablet to avoid stomach upset.
If you are taking high doses of Zerofen 100mg Tablet or a long-term treatment or both, then you should restrict or avoid alcohol. The reason being, taking both of them together increases your chances of ulcers and bleeding. It may also result in holes in the stomach and intestine (gastrointestinal perforation). These are serious side effects of Zerofen 100mg Tablet which may be life-threatening. Discuss with your doctor if you are not sure.
Avoid taking Zerofen 100mg Tablet during pregnancy as it may put your pregnancy and your unborn baby at risk. There have been reports of miscarriage and defects in the heart of the baby. But, if it is necessary to take it, then your doctor may prescribe a low dose for the shortest duration. This is applicable for the first 6 months of pregnancy. Zerofen 100mg Tablet should not be given during the last 3 months of pregnancy as it may cause various defects in the baby and may also prolong labor.
Yes, Zerofen 100mg Tablet may cause sleepiness. It may also cause dizziness, visual disturbances, drowsiness, fits, and spinning sensation. Do not drive or operate heavy machinery if you experience these symptoms. Consult your doctor if you are not sure.
Take Zerofen 100mg Tablet only as long as advised by your doctor. Do not take it for longer than the recommended period of time. Long-term treatment with Zerofen 100mg Tablet and at high doses can cause an increased risk of heart attack, stroke, ulcers, bleeding, or holes in the stomach and intestine. These symptoms can occur at any time without warning.

Fact Box

Chemical Class

Benzophenones

Habit Forming

No

Therapeutic Class

PAIN ANALGESICS

Action Class

NSAID's- Non-Selective COX 1&2 Inhibitors (propionic acid)

References

  1. Furst DE, Ulrich RW, Varkey-Altamirano C. Nonsteroidal Anti-Inflammatory Drugs, Disease Modifying Antirheumatic Drugs, Nonopioids Analgesics, & Drugs Used in Gout. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 627.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 759-60.
  3. Ketoprofen. Philadelphia, Pennsylvania: Wyeth Pharmaceuticals Inc; 2007. [Accessed 02 Apr. 2019] (online) Available from:
  4. Central Drugs Standard Control Organisation (CDSCO). [Accessed 02 Apr. 2019] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Sanvi Pharma
Address: # 1-15-3/A/1, Madinaguda Village, , Rangareddy Dist, Hyderabad. Telangana - 500050, India

Vendor Details

Country of origin: India
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