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Ketoprofen is used in the management of inflammation and pain due to any arthritis including rheumatoid arthritis (inflammatory disorder that typically affects the small joints in hands and feet), osteoarthritis (damage to the cushioning cartilage between the joints), ankylosing spondylitis (pain due to inflammation in spine or backbone), and acute gout (painful, red, swollen joints due to deposition of uric acid in the joints). It is also used in painful menstruation (dysmenorrhea) and for control of pain and inflammation following injuries that affect bones and muscles (orthopedic) surgery.

How it works

Ketoprofen is a pain killer medication belongs to group of medicines called nonselective cyclooxygenase inhibitors (traditional non-steroidal anti-inflammatory drug [NSAID]). It inhibits the synthesis of chemicals like prostaglandin and thromboxane that results in the reduction of fever, formation of blood clots, pain and inflammation.

Common side effects

Nausea, Heartburn, Indigestion, Stomach pain, Vomiting


No medicine available

Expert advice

  • Tell your doctor if you are or planning to become pregnant or are breastfeeding.
  • Do not drive or operate any machinery because you may feel sleepy or dizzy while being treated with ketoprofen.
  • Do not consume alcohol while taking ketoprofen as it may cause serious side effects.
  • Caution should be taken when giving ketoprofen to children younger than 18 years or elderly 65 years of age or older.

Frequently asked questions


Q. Is ketoprofen safe?
Ketoprofen is relatively safe if used at prescribed doses for the prescribed duration as advised by your doctor
Q. Is ketoprofen a blood thinner?
No, ketoprofen is not a blood thinner.
Q. Is ketoprofen a controlled substance?
No, ketoprofen is not a controlled substance.
Q. Is ketoprofen the same as ibuprofen?
Both ketoprofen and ibuprofen belongs to the same class, i.e non-steroidal anti-inflammatory drug (NSAID), but their effect may vary upon individual condition or response.
Q. Can I take ketoprofen with Aspirin (acetylsalicylic acid), Tylenol (acetaminophen), Vicodin (acetaminophen and hydrocodone), hydrocodone, ibuprofen, paracetamol, or tramadol?
Ibuprofen should not be given with ketoprofen. It is not reported to interact with Aspirin, Tylenol, Vicodin, hydrocodone, paracetamol, or tramadol. Please follow the advice of the doctor regarding their simultaneous use.
Q. Does ketoprofen contain aspirin, ibuprofen, or ketamine?
No, ketoprofen does not contain aspirin, ibuprofen, or ketamine.
Q. Does ketoprofen cause drowsiness?
Yes, ketoprofen may cause drowsiness. Please consult your doctor before taking the drug.

Content on this page was last updated on 30 September, 2016, by Dr. Varun Gupta (MD Pharmacology)