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MD Pharmacology, MBBS
Last updated
19 Jan 2026 | 02:50 PM (IST)

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Yees 40mg Tablet

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Product introduction

Yees 40mg Tablet is used to treat conditions related to excessive stomach acid production, such as gastroesophageal reflux disease (GERD), peptic ulcer disease, and Zollinger-Ellison syndrome. It reduces the amount of acid produced in the stomach and provides relief from symptoms and promotes healing.

Yees 40mg Tablet can also be used to prevent stomach ulcers caused by certain medications, such as nonsteroidal anti-inflammatory drugs (NSAIDs). Take it in the exact dose and duration prescribed by your doctor. It is usually taken on an empty stomach, preferably in the morning or at least 1 hour before a meal. Continue taking the medicine even if your symptoms disappear until the doctor says it is okay to stop. If you are taking this medicine for a long time, your doctor may carry out regular tests to check your levels of magnesium, which can fall with this medicine.


Common side effects include headache, constipation or diarrhea, stomach pain, and nausea. These tend to be mild, but talk to your doctor if they bother you or do not go away. The risk of side effects may increase the longer you take this medicine. You may be more likely to have a broken bone if you take it for a long time. It is best to avoid foods that seem to make your symptoms worse, such as rich, spicy, and fatty foods. Cutting down on caffeinated drinks, such as tea, coffee, and cola, as well as alcohol, may also help.


Yees 40mg Tablet may not be suitable for some people. Before taking this medicine, you need to tell your doctor if you have severe liver problems, are taking medicines for HIV, have had an allergic reaction to similar medicines in the past, or have osteoporosis. Alcohol does not interfere with the way Yees 40mg Tablet works; however, drinking alcohol makes your stomach produce more acid than normal. This medicine can make you feel dizzy, sleepy, or affect your vision. If this happens, do not drive, cycle, or use machinery or tools until you feel better. This medicine is not usually recommended during pregnancy and breastfeeding.


Uses of Yees Tablet

Benefits of Yees Tablet

In Acidity

Yees 40mg Tablet helps relieve the discomfort caused by excessive stomach acid, such as burning sensations, sour stomach, or acid regurgitation. By reducing acid production, it soothes the stomach lining and prevents irritation, providing fast and lasting relief. For individuals suffering from frequent acidity, Yees 40mg Tablet improves their quality of life by enabling them to enjoy meals and daily activities without the discomfort and inconvenience of acid-related symptoms.

In Gastroesophageal reflux disease (Acid reflux)

Yees 40mg Tablet helps manage GERD by reducing the flow of stomach acid into the esophagus, which causes the burning sensation of heartburn and other acid reflux symptoms. This helps alleviate discomfort, protects the esophagus from long-term damage, and minimizes complications like inflammation or narrowing of the esophagus.

In Peptic ulcer disease

In individuals with peptic ulcer disease, Yees 40mg Tablet helps reduce stomach acid levels, which allows the ulcers to heal more effectively and prevents further damage to the stomach lining. It also helps reduce symptoms like pain, nausea, and indigestion. By promoting healing and preventing the recurrence of ulcers, Yees 40mg Tablet improves patients’ comfort and restores normal digestion, improving their overall well-being.

In Treatment of Zollinger-Ellison syndrome

Zollinger-Ellison syndrome is a rare disorder where excessive stomach acid production can cause severe symptoms like diarrhea, abdominal pain, and ulcers. Yees 40mg Tablet reduces this overproduction of acid, helping to control symptoms and prevent complications like bleeding ulcers. By managing acid levels effectively, the medicine allows patients to lead a more comfortable and active life without being constantly disrupted by severe digestive symptoms.

Side effects of Yees Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Yees

  • Vomiting
  • Nausea
  • Diarrhea
  • Abdominal pain
  • Flatulence
  • Headache
  • Fundic gland polyps

How to use Yees Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Yees 40mg Tablet is to be taken on an empty stomach.

How Yees Tablet works

Yees 40mg Tablet is a proton pump inhibitor (PPI). It works by reducing the amount of acid in the stomach which helps in relief of acid related indigestion and heartburn.

Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Yees 40mg Tablet. Please consult your doctor.
Pregnancy
SAFE IF PRESCRIBED
Yees 40mg Tablet is generally considered safe to use during pregnancy. Animal studies do not indicate harmful effects. However, there are limited human studies.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Yees 40mg Tablet during breastfeeding is not available. Please consult your doctor.
Driving
SAFE
Yees 40mg Tablet does not usually affect your ability to drive.
Kidney
CONSULT YOUR DOCTOR
There is limited data available on the use of Yees 40mg Tablet in patients with kidney disease. Please consult your doctor.
Liver
CAUTION
Yees 40mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment may be needed.

What if you forget to take Yees Tablet?

If you miss a dose of Yees 40mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Yees 40mg Tablet
₹11.34/Tablet
Esomefol Tablet
Leeford Healthcare Ltd
₹6.7/tablet
41% cheaper
NexPRO 40 Tablet
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₹12.5/tablet
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Sompraz 40 Tablet
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₹11.25/tablet
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racipER 40 Tablet
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₹11.25/tablet
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Esoz Tablet
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Quick tips

  • Yees 40mg Tablet is best taken 1 hour before a meal, preferably in the morning.
  • Avoid drinking alcohol, smoking cigarettes, and excessive intake of carbonated beverages/soft drinks, citrus juices, fried food, and caffeinated beverages like tea and coffee.
  • Inform your doctor if you get watery diarrhea, fever, or stomach pain that does not go away.
  • Inform your doctor if you do not feel better after taking it for 14 days, as you may be suffering from some other problem that needs attention.
  • Long-term use of Yees 40mg Tablet can cause weak bones and a deficiency of minerals such as magnesium. Take adequate dietary intake of calcium and magnesium or their supplements as prescribed by your doctor.

Fact Box

Chemical Class
Sulfinylbenzimidazoles
Habit Forming
No
Therapeutic Class
GASTRO INTESTINAL
Action Class
Proton-Pump Inhibitors

Interaction with drugs

Taking Yees with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Please consult with your doctor. Doctor may monitor liver function and blood cell counts. Concurrent use may increase the risk of serious side effects of Methotrexate.
Please consult with your doctor. Doctor may monitor liver function and blood cell counts. Concurrent use may increase the risk of serious side effects of Methotrexate.
Do not consume Erlotinib with Esomeprazole. Esomeprazole may reduce blood levels of Erlotinib.
Please consult with your doctor. Doctor may monitor liver function and blood cell counts. Concurrent use may increase the risk of serious side effects of Methotrexate.
Please consult with your doctor. Doctor may monitor liver function and blood cell counts. Concurrent use may increase the risk of serious side effects of Methotrexate.

Patient concerns

Heartburn Mental disorder Depression Frequent persistent heartburn Gastroesophageal reflux disease Irritable bowel syndrome Indigestion Back flow of acid from stomach Difficulty in swallowing Inflammation of esophagus Excess acid secretion by stomach Intestinal or stomach ulcers
Dr. Sunil Sekhri
Diabetology
You need to be examined in clinic to reach a diagnosis and then appropriate medicine can be prescribed
Moderate Throat Pain in left side Moderate Ear pain. Acid reflux too often
Dr. Vijay Verma
ENT
it may be due to acidity also you may have got some ulcer or infection in that region visit ent specialist near you for proper examination

FAQs

What is the best time to take Yees 40mg Tablet?

Usually, Yees 40mg Tablet is taken once a day, first thing in the morning. If you take Yees 40mg Tablet twice a day, take 1 dose in the morning and 1 dose in the evening. The tablets should be swallowed whole (remember not be chewed or crushed) and taken at least 1 hour before a meal with some water.

Can I take antacids along with Yees 40mg Tablet?

Yes, you can take antacids along with Yees 40mg Tablet. Take it 2 hours before or after you take Yees 40mg Tablet.

Can I take Yees 40mg Tablet for a long term?

Yees 40mg Tablet is usually prescribed for short-term use only. However, if need arises, such as for treating peptic ulcer disease and Zollinger-Ellison syndrome (ZES), Yees 40mg Tablet may be prescribed for a long-term duration as well. Long-term use may carry an increased risk for side effects and must be discussed with the doctor. Please use Yees 40mg Tablet as advised by your doctor and under their supervision.

Can I stop taking Yees 40mg Tablet if I feel better?

If you have been taking Yees 40mg Tablet for a long time, stopping it abruptly may lead to increased acid production, thereby worsening your symptoms. Therefore, you must discuss any dose changes or if you wish to come off Yees 40mg Tablet.

What are the long term side effects of Yees 40mg Tablet?

If Yees 40mg Tablet is used for more than 3 months, certain long-term side effects may be seen. The most important of these is low magnesium levels in your blood, which may make you feel tired, confused, dizzy, or shaky. You may also have muscle twitches or an irregular heartbeat. If the use is further prolonged for more than a year, you may have an increased risk of bone fractures, stomach infections, and vitamin B12 deficiency. Vitamin B12 deficiency can make you anemic, as a result of which you may feel more tired, weak, or pale. Additionally, you may have palpitations, shortness of breath, lightheadedness, indigestion, loss of appetite, flatulence (gas), or nerve problems such as numbness, tingling, and problem in walking.

Can I take alcohol with Yees 40mg Tablet?

No, alcohol intake is not advised with Yees 40mg Tablet. Alcohol itself does not affect the working of Yees 40mg Tablet, but it can increase the acid production. This may further cause worsening of your symptoms.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Esomeprazole [Prescribing Information]. Wilmington, DE: AstraZeneca Pharmaceuticals; 2014. [Accessed 28 Mar. 2019] (online) Available from: External Link
  2. Central Drugs Standard Control Organisation (CDSCO). [Accessed 28 Mar. 2019] (online) Available from: External Link
  3. Esomeprazole [Prescribing Information]. Haridwar, Uttarakhand: Pure & Cure Healthcare Pvt. Ltd.; 2023. [Accessed 22 Jun. 2023] (online) Available from: External Link
  4. Esomeprazole [Prescribing Information]. Haridwar, Uttarakhand: Pure & Cure Healthcare Pvt. Ltd.; 2023. [Accessed 22 Jun. 2023] (online) Available from: External Link
  5. Esomeprazole [Summary of Product Characteristics]. Waterford, Ireland: Haleon Ireland Dungarvan Limited; 2025.

Marketer details

Name: Alkem Laboratories Ltd
Address: Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.
Country of origin: India
Expires on or after: April, 2026

A licensed vendor partner from your nearest location will deliver Yees 40mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

MRP
113.44
Inclusive of all taxes
10.0 tablets in 1 strip
The price displayed is the MRP (inclusive of applicable taxes). Any additional fee (such as shipping fee, handling and/or platform fee etc.) will be clearly disclosed before you complete your purchase.
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Yees 40mg Tablet
Yees 40mg Tablet
strip of 10 tablets
Get by Sunday, 25 January
Contains: Esomeprazole (40mg)
by Alkem Laboratories Ltd
₹113.44
₹11.34 per tablet
44% lower price
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Esomifyl 40mg Tablet
Esomifyl 40mg Tablet
strip of 10 tablets
Get by Thu, 22 Jan
Contains: Esomeprazole (40mg)
by Leeford Healthcare Ltd
₹63.1
₹6.31 per tablet
Get by Sunday, 25 January
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