Xtandi 40mg Soft Capsule is used in the treatment of cancer of the prostate gland. It may be also used to treat other conditions, as determined by the doctor. It works by blocking the effects of male hormones such as testosterone.

Xtandi 40mg Soft Capsule should be taken with or without food, preferably at a fixed time every day. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Headache, hot flashes, weakness and high blood pressure is very common side effect of this medicine. Other than this, fractures, falls, dry skin, pruritus,decreased appetite, and constipation might be observed as side effects. Regular blood tests are required to check your blood cells along with liver function during treatment with this medicine. It makes your skin more sensitive towards sunlight, hence take extra caution while going out.

Before taking it, tell your doctor if have diabetes, seizures, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. You may be asked for regular monitoring of blood glucose level while on treatment.

Uses of Xtandi Capsule

Prostate cancer

Benefits of Xtandi Capsule

In Prostate cancer

Prostate gland is a small walnut-sized gland that produces a fluid called seminal fluid that nourishes and transports sperms in males. The most common symptom of prostate cancer is difficulty with urination, but sometimes there are no symptoms at all. Xtandi 40mg Soft Capsule decreases or stops the growth of cancer cells by decreasing the amount of testosterone (natural hormone in males) in men. This also relieves difficulty in passing urine and makes it easier for you to urinate.

Side effects of Xtandi Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Xtandi

Headache
Hot flashes
Weakness
High blood pressure
Fatigue
Decreased appetite
Constipation
Dry skin
Itching
Fall
Fracture

How to use Xtandi Capsule

Take this medicine in the dose and duration as advised by your doctor. Xtandi 40mg Soft Capsule may be taken with or without food, but it is better to take it at a fixed time.

How Xtandi Capsule works

Xtandi 40mg Soft Capsule is an antiandrogens. It works by blocking the effect of the natural male hormones on the growth of prostate cells.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Xtandi 40mg Soft Capsule.

Pregnancy

CONSULT YOUR DOCTOR

Xtandi 40mg Soft Capsule is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

UNSAFE

Xtandi 40mg Soft Capsule is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

UNSAFE

Xtandi 40mg Soft Capsule may cause side effects which could affect your ability to drive.

Kidney

CAUTION

Xtandi 40mg Soft Capsule should be used with caution in patients with severe kidney disease. Dose adjustment of Xtandi 40mg Soft Capsule may be needed. Please consult your doctor.

Liver

CAUTION

Xtandi 40mg Soft Capsule should be used with caution in patients with severe liver disease. Dose adjustment of Xtandi 40mg Soft Capsule may be needed. Please consult your doctor.

What if you forget to take Xtandi Capsule?

If you miss a dose of Xtandi 40mg Soft Capsule, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Xtandi 40mg Soft Capsule

₹2905.34/Capsule

Azel 40mg Capsule

Dr Reddy's Laboratories Ltd

₹261/capsule

91% cheaper

Enzamide 40mg Capsule

Intas Pharmaceuticals Ltd

₹320.36/capsule

89% cheaper

Enshrink Capsule

Ytiliga Private Limited

₹297.79/capsule

90% cheaper

Encrpc 40mg Capsule

Intas Pharmaceuticals Ltd

₹702.86/capsule

76% cheaper

Enzurem 40 Capsule

Curemart Pharma Pvt Ltd

₹657.89/capsule

77% cheaper

View all substitutes

Quick tips

You have been prescribed Xtandi 40mg Soft Capsule for the treatment of prostate cancer.
Take it with or without food, preferably at the same time every day.
Do not drive or do anything requiring concentration unless you know how Xtandi 40mg Soft Capsule affects you.
It may cause your skin to become light sensitive. Avoid direct exposure to excessive sunlight and use sunscreen when outdoors.
If you are diabetic, monitor your blood glucose regularly while taking Xtandi 40mg Soft Capsule.
Your doctor may want you to have regular blood tests to monitor your liver function while you are taking this medicine. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.
Do not stop taking the medication without talking to your doctor first.

Fact Box

Chemical Class

Phenylimidazolidine Derivative

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Patient concerns

I have problem of frequent urination at night. My father had same at his time.Doctor told me that I am having BPH.Also I went through PSA whose result is 1.8 increased prostate gland size is 40 which came in ultrasound report .When doctor did some test by inserting his finger in my rectal area I felt abnormal pain.doctor asked me to go for a culture test so as to check which can be the best medicine for BPH for me. Kindly suggest if it can be something else like prostate cancer.

Dr. Vijay Sharnangat

Medical Oncology and Hematology

May not be prostate cancer, it is only begnin enlargement of prostate.

Do i have prostrate cancer. Married but now having difficulty in having relation with wife. Penis not hard in the morning. Having problem with self spontaneous erection. Please help. God Bless.

Dr. Sanjay Singh Rai

Medical Oncology and Hematology

Not a symptom of prostate cancer

User feedback

What are you using Xtandi Capsule for?

Prostate canc*

100%

*Prostate cancer

How much was the improvement?

Excellent

67%

Average

33%

What were the side-effects while using Xtandi 40mg Soft Capsule?

Weakness

100%

How do you take Xtandi Capsule?

Empty stomach

100%

Please rate Xtandi 40mg Soft Capsule on price

Expensive

100%

Related lab tests

Prostate Specific Antigen (Free) PSA

Prostate Specific Antigen (Total) PSA

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5 ★

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5 ★

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 474-75.
Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:
Enzalutamide. Netherlands: Astellas Pharma Europe B.V.; [Accessed on 27 Mar. 2019] (online) Available from:
PubChem. Enzalutamide. [Accessed 27 Mar. 2019] (online) Available from:
CiplaMed. Enzalutamide [Prescribing Information]. 2022. [Accessed 20 Feb. 2024] (online) Available from:

Marketer details

Name: Astellas Pharma Inc

Address: Astellas Pharma India Pvt Ltd, 301, 3rd Floor, C and B Square, 127 Andheri Kurla Road, Chakala, Andheri East, Mumbai 400 069.

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.