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Composition for XARB H

Irbesartan(150 mg),Hydrochlorothiazide(12.5 mg)

food interaction for XARB H

alcohol interaction for XARB H

pregnancy interaction for XARB H

lactation interaction for XARB H

There is no data available. Please consult doctor before consuming the drug.
Taking Hydrochlorothiazide with alcohol may have additive effects in lowering blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate.
Xarb h 150 mg/12.5 mg tablet is unsafe to use during pregnancy.
There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
Unknown. Human and animal studies are not available. Please consult your doctor.


Irbesartan(150 mg)


Irbesartan is used to reduce high blood pressure (hypertension) and in the treatment of kidney disease caused by diabetes in type 2 diabetes and hypertensive patients.

How it works

Irbesartan belongs to a class of drugs named as angiotensin II receptor antagonists. It acts on the blood vessels by blocking certain substance that is responsible for tightening of the blood vessels, allowing them to relax and pump blood effectively.

Common side effects

Vomiting, Nausea, Orthostatic hypotension (low blood pressure), Dizziness, Fatigue, Increased potassium level in blood, Muscle pain
Hydrochlorothiazide(12.5 mg)


Hydrochlorothiazide is used to treat high blood pressure (hypertension). It also treats fluid retention (edema) due to congestive heart failure or cirrhosis of liver or kidney disorder.

How it works

Hydrochlorothiazide belongs to class of medications called thiazide diuretics. It acts by eliminating the fluid and salts from the body. It works on the kidneys to produce more urine which removes extra water and certain salts from the body which in turn lowers blood pressure and swelling.

Common side effects

Increased sensitivity to light, Excessive thirst, Abnormal heart rhythm, Skin rash, Allergic reaction, Altered blood lipids, Convulsion, Drowsiness, Dry mouth, Electrolyte imbalance, Vomiting, Gastrointestinal disorder, Gout, Headache, Increased glucose level in blood, Increased uric acid level in blood, Decreased potassium level in blood, Decreased magnesium level in blood, Decreased sodium level in blood, Decreased blood pressure, Lethargy, Muscle pain, Weakness


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Expert advice for XARB H

  • Do not change your dose or stop taking irbesartan, even if you are feeling well, as this may worsen your symptoms.
  • Use of Irbesartan may cause dizziness, light-headedness, or fainting; you should avoid driving or operating heavy machinery under such circumstances.
  • Irbesartan may cause a serious side effect called angioedema (swelling of the hands, face, lips, eyes, throat, or tongue; difficulty swallowing or breathing; or hoarseness). If you experience any such symptoms, inform your doctor immediately.
  • Before you take Irbesartan, inform your doctor if you suffer from kidney/heart problems or are being treated for diabetic kidney disease.
  • If you are or planning to undergo a surgery involving anesthesia, inform your doctor that you are taking Irbesartan.
  • Tell your doctor if you are taking or have recently taken or might take any other medicines along with Irbesartan.
  • Tell your doctor if you are or planning to become pregnant or are breastfeeding.

Frequently asked questions for XARB H


Q. Is irbesartan an alpha /a beta blocker/ calcium channel blocker/an ace inhibitor/a statin/ diuretic/ nitrate?
No. Irbesartan is an angiotensin II receptor blocker.
Q. Is irbesartan safe? 
Yes. Irbesartan is safe if used at prescribed doses for the prescribed duration as advised by your doctor.
Q. Is irbesartan and losartan the same? 
No. Both are different drugs of the same class; however, they differ in their pharmacokinetic profile.
Q. Can I take ibuprofen with irbesartan?
Use of ibuprofen with irbesartan may reduce the effects of irbesartan in lowering blood pressure. In addition, if this combination is taken frequently, it may affect the kidney function.
Q. Can I take paracetamol with irbesartan?
Yes. You can take paracetamol with irbesartan.
Q. Can I take aspirin with irbesartan?
Use of aspirin with irbesartan may reduce the effects of irbesartan in lowering blood pressure. In addition, if this combination is taken frequently, it may affect your kidney function.
Q. Does irbesartan lower heart rate?
Yes. Irbesartan may lower your heart rate.
Q. Does irbesartan cause constipation/ weight gain/ hair loss/ erectile dysfunction / impotence/ diarrhea/ ringing in the ears/ depression?
No. Irbesartan does not cause any of the above side effects. However, if you experience such side effects please consult your doctor immediately.


Q. Hydrochlorothiazide is a diuretic,which increases the excretion of urine?
Patients should follow the advice of the doctor regarding its use.
Q. Is hydrochlorothiazide a statin/ opiate?
No.It is the derivative of chlorothiazide.
Q. Is hydrochlorothiazide bad for your kidneys?
No.Hydrochlorthiazide is a safe drug at prescribed dose by your doctor. Consult your doctor if you have kidney disease and follow the advice of the doctor regarding its use.
Q. Can I take hydrochlorothiazide with lisinopril/ ibuprofen/ synthroid/ aspirin/ potassium/ phentermine/ losartan/ naproxen/ magnesium/ vitamins?
Taking other medicines may alter the effects of hydrochlorothiazide. Always consult your doctor for the change of dose regimen or an alternative drug of choice that may strictly be required.
Q. Does hydrochlorothiazide cause diabetes/ erectile dysfunction/ weight loss/ gout/ constipation/tinnitus/ potassium loss?
Hydrochlorothiazide causing these side effects is rare or uncommon. However, consult your doctor if you experience any of these side effects.
Q. Does hydrochlorothiazide have sulfa in it?
Yes.Hydrochlorothiazide has sulfa and it is chemically known as 6-chloro- 3, 4-dihydro-2 H-1, 2, 4-benzothiadiazine-7-sulfonamide 1, 1-dioxide.
Q. Does hydrochlorothiazide clean your system?
No.Hydrochlorothiazide reduces extra fluid in the body.


Content on this page was last updated on 24 June, 2016, by Dr. Varun Gupta (MD Pharmacology)