Wiklyone 100 Tablet

Reviewed By Dr. Rajeev Sharma, MBA, MBBS

Last updated on 13 Nov 2025 | 01:32 PM (IST)

Wiklyone 100 Tablet is an oral weekly drug for the control of type 2 diabetes. It acts by inhibiting the enzyme DPP-4, which favors enhanced release of insulin and suppressed production of sugar in the liver, thus enhancing the control of blood sugar after meals.

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₹503 MRP ₹556.8810% off

Wiklyone 100 Tablet is currently sold out

Same composition alternative:

Onetrela 100 Tablet

₹379~~₹420~~

25% cheaper alternative available from Alkem Laboratories

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Wiklyone 100 Tablet

strip of 4 tablets

₹503

~~₹556.88~~

Same composition

Onetrela 100 Tablet

strip of 4 tablets

Trelagliptin (100mg)

by Alkem Laboratories Ltd

Get by 2pm

₹379

₹80.5 per tablet

₹322

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₹1200

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General Information

Contains

Trelagliptin (100mg)

Marketer

Best Biotech

Storage

Store below 30°C

The content is shown in English

Product introduction

In order for Wiklyone 100 Tablet to help regulate blood sugar levels, take it precisely as directed, usually once a week. Skipping doses will limit its glucose-control ability. To remain consistent, select a regular day of the week for your dose, and consider putting reminders in place. Take it with food, and have follow-ups regularly with your doctor to check on your response and modify treatment where necessary.

Common side effects of Wiklyone 100 Tablet include hypoglycemia, blisters, and bowel obstruction. If side effects persist or worsen, consult your doctor. Always use as directed to minimize risks and ensure safe use.

Wiklyone 100 Tablet is contraindicated in patients with a known hypersensitivity to the drug or any of its components. It should be used cautiously in people with a history of pancreatitis, kidney impairment, or heart problems. Although rare, serious allergic reactions and joint pain have been reported. It is not recommended for use in type 1 diabetes or diabetic ketoacidosis. Patients should inform their doctor about all existing conditions and current medications to avoid adverse interactions.

Uses of Wiklyone Tablet

Treatment of Type 2 diabetes mellitus

Benefits of Wiklyone Tablet

Treatment of Type 2 diabetes mellitus
Type 2 diabetes is a chronic condition in which the body either fails to make enough insulin or cannot use it properly, resulting in high blood sugar levels. If left uncontrolled, diabetes can lead to severe complications such as heart disease, kidney impairment, and nerve damage.

Wiklyone 100 Tablet controls blood glucose levels by enhancing the activity of incretin hormones, which enhance insulin secretion postprandially and lower the liver's glucose output. Its distinct benefit is its once-weekly dosing, which provides convenience and could also ensure patient compliance. Through more level maintenance of blood sugar, it aids in better long-term glucose control and lowers the risk of diabetic complications.

Side effects of Wiklyone Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Wiklyone

Hypoglycemia (low blood glucose level)
Blisters
Intestinal obstruction

How to use Wiklyone Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Wiklyone 100 Tablet should be taken with or after food.

How Wiklyone Tablet works

Wiklyone 100 Tablet is a dipeptidyl peptidase-4 (DPP-4) inhibitor. It inhibits the DPP-4 enzyme, which would otherwise be responsible for degrading incretin hormones such as GLP-1 and GIP. These hormones regulate blood sugar by enhancing insulin secretion and suppressing glucagon after meals. By extending the effects of incretins, it enhances insulin secretion during meals and decreases liver-sugar production. This provides improved regulation of blood glucose, especially postprandially. Its long duration enables once-weekly administration, improving convenience and compliance.

All substitutes for Wiklyone 100 Tablet

For information purposes only. Consult a doctor before taking any medicine.

Trelaglip 100 Tablet

by Zuventus Healthcare Ltd

₹128/tablet

2% costlier

Onetrela 100 Tablet

by Alkem Laboratories Ltd

₹94.75/tablet

25% cheaper

Quick tips

Monitor your blood sugar regularly, especially if combining with other antidiabetic drugs.
Watch for signs of pancreatitis, severe stomach pain, nausea, or vomiting, and report them immediately.
Inform your doctor if you have kidney or liver issues, as dose adjustments may be needed.
Continue with healthy eating and physical activity, as Wiklyone 100 Tablet works best when paired with lifestyle changes.
If you feel unusually tired, dizzy, or develop a skin rash, seek medical help to rule out rare side effects.
Make sure to attend regular check-ups to monitor HbA1c and other diabetes-related health markers.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Wiklyone 100 Tablet

Pregnancy

CONSULT YOUR DOCTOR

The safety of Wiklyone 100 Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CONSULT YOUR DOCTOR

Wiklyone 100 Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

CAUTION

Wiklyone 100 Tablet may affect your driving ability if your blood sugar becomes too low or too high. Monitor your blood glucose and avoid driving if affected.

Kidney

CAUTION

Wiklyone 100 Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

CAUTION

Wiklyone 100 Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.

Frequently asked questions

What happens if I miss a dose of Wiklyone 100 Tablet?

If you miss a dose, take it as soon as you remember unless it is close to the next scheduled dose. Never double up.

Does Wiklyone 100 Tablet cause weight gain?

It is generally weight-neutral, which means it does not typically cause weight gain.

Is Wiklyone 100 Tablet safe for older adults?

It can be used in older adults but may require dose adjustment, especially in those with kidney issues.

Can I drink alcohol while on Wiklyone 100 Tablet?

It is best to limit alcohol intake as it can affect blood sugar levels and increase the risk of side effects.

Can I stop taking Wiklyone 100 Tablet if my sugar levels are normal?

No, always consult your doctor before stopping or changing your medication.

Does Wiklyone 100 Tablet cure diabetes?

No, it helps manage blood sugar levels but does not cure diabetes.

Fact Box

Chemical Class

Benzonitriles

Habit Forming

Therapeutic Class

ANTI DIABETIC

Action Class

Dipeptidyl Peptidase-4 (DPP-4) Inhibitors

Related lab tests

Glucose - Fasting Blood

Glucose - Postprandial Blood

Glycosylated Hemoglobin

References

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Best Biotech
Address: 76-13-18B/6A&B, Beside Lane Of Samskruthi Function Hall, Urmilanagar, Opp Avsr Sky Court, Bhavanipuram, Vijayawada-520012, Andhra Pradesh.

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Provide right medicines

Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose

In accordance with the law

Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945

Wiklyone 100 Tablet

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Wiklyone Tablet

Benefits of Wiklyone Tablet

Side effects of Wiklyone Tablet

How to use Wiklyone Tablet

How Wiklyone Tablet works

All substitutes for Wiklyone 100 Tablet

Trelaglip 100 Tablet

Onetrela 100 Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

What happens if I miss a dose of Wiklyone 100 Tablet?

Does Wiklyone 100 Tablet cause weight gain?

Is Wiklyone 100 Tablet safe for older adults?

Can I drink alcohol while on Wiklyone 100 Tablet?

Can I stop taking Wiklyone 100 Tablet if my sugar levels are normal?

Does Wiklyone 100 Tablet cure diabetes?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Glucose - Fasting Blood

Glucose - Postprandial Blood

Glycosylated Hemoglobin

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests