Volane Source 450 Tablet
Product introduction
Volane Source 450 Tablet is used to treat cytomegalovirus (CMV) infection of the retina (retinitis) in adult patients with acquired immunodeficiency syndrome (AIDS). It is also used for the prevention of CMV infection in patients who have received an organ transplant from a CMV-infected donor.
Volane Source 450 Tablet should be taken in the dose and duration as advised by your doctor. Do not skip any doses and finish the full course of treatment even if you feel better. It should be taken with food. You should drink plenty of water while on treatment with this medicine, as it helps prevent dehydration and kidney damage.
Volane Source 450 Tablet may cause a few common side effects like diarrhea, vomiting, anemia, low white blood cells, low platelet levels, insomnia, and vomiting. Inform your doctor if these side effects persist for a longer duration.
Before you start Volane Source 450 Tablet, let your doctor know if you have any medical conditions. Let your doctor also know about all the medications you are taking, as some medicines may interact with Volane Source 450 Tablet. Please consult your doctor if you are pregnant, planning to conceive, or breastfeeding.
Uses of Volane Tablet
- Treatment of Cytomegalovirus Infection
Benefits of Volane Tablet
In Treatment of Cytomegalovirus Infection
Cytomegalovirus infection is a common virus infection that may have no symptoms at all or may have symptoms like fever and fatigue. Severe infection may show symptoms involving the eyes, brain, or other internal organs. This virus is spread through sexual and nonsexual contact with body secretions in people who are immunocompromised or those who have undergone a transplant. Volane Source 450 Tablet helps prevent the multiplication of the infection-causing virus and treats the infection. Keep taking it in the dose and duration prescribed by the doctor to get maximum benefit.
Side effects of Volane Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Volane
- Diarrhea
- Fever
- Fatigue
- Nausea
- Tremors
- Decreased white blood cell count (neutrophils)
- Anemia (low number of red blood cells)
- Decreased white blood cell count
- Low blood platelets
- Headache
- Insomnia (difficulty in sleeping)
- Vomiting
- Urinary tract infection
How to use Volane Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Volane Source 450 Tablet is to be taken with food.
How Volane Tablet works
Volane Source 450 Tablet is an antiviral medication. It prevents the multiplication of viruses in human cells. This stops the virus from producing new viruses and clears up your infection.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Volane Source 450 Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Volane Source 450 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Volane Source 450 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Volane Source 450 Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Volane Source 450 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Volane Source 450 Tablet may be needed. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Volane Source 450 Tablet in patients with liver disease. Please consult your doctor.
What if you forget to take Volane Tablet?
If you miss a dose of Volane Source 450 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Volane Source 450 Tablet
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Quick tips
- Take Volane Source 450 Tablet exactly as prescribed by your doctor to effectively control CMV retinitis and prevent the worsening of the infection.
- Regular blood tests may be required to monitor your blood cell counts, as Volane Source 450 Tablet can cause low white blood cells (leukopenia) and low platelets (thrombocytopenia).
- Inform your doctor if you experience unusual bleeding, persistent fever, vision changes, or severe fatigue, as these may indicate serious side effects.
- Use effective contraception during treatment and for at least 90 days after stopping the medication, as Volane Source 450 Tablet may cause birth defects.
Fact Box
Chemical Class
Nucleoside analog
Habit Forming
No
Therapeutic Class
ANTI INFECTIVES
Action Class
Antiviral Agents (Non-HIV)
Interaction with drugs
Taking Volane with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
If concurrent use is essential, your doctor may monitor your tacrolimus levels, potassium levels and kidney function closely. They may adjust the doses as per the observations.
Co
If concurrent use is essential, your doctor may monitor your kidney function closely.
Concurrent use may increase the risk of kidney damage.
If concurrent use is essential, please consult your doctor. They may monitor your kidney's functioning closely. Amphotericin B may slow down the removal of Valganciclovir from the
Do not consume Valganciclovir with Co-trimoxazole. If concurrent use is essential, your doctor may monitor your blood cell count frequently and adjust the doses as per the observat
If concurrent use is essential, please consult your doctor. They may monitor your kidney's functioning closely. Cidofovir may slow down the removal of Valganciclovir from the body.
Patient concerns
FAQs
What is valganciclovir used for?
Volane Source 450 Tablet is used for the treatment of cytomegalovirus (CMV) infection of the retina (retinitis) in adult patients with acquired immunodeficiency syndrome (AIDS). It is also used for the prevention of CMV infection in patients who have received an organ transplant from a CMV-infected donor.
How does valganciclovir work?
After being taken orally, Volane Source 450 Tablet gets converted into ganciclovir by liver and intestinal enzymes, which then prevents the growth and spread of cytomegalovirus.
Does Volane Source 450 Tablet cover herpes simplex virus (HSV)?
Volane Source 450 Tablet can also be used for the treatment of herpes simplex virus (HSV) infection. Please follow the doctor's advice regarding its use.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Acosta EP, Flexner C. Antiviral Agents (Nonretroviral). In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1603-605.
- Safrin S. Antiviral Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 852.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1446-47.
- Alganciclovir [Prescribing Information]. South San Francisco, California: Genentech USA; 2010. [Accessed 01 Apr. 2019] (online) Available from:
- Valgaciclovir [Prescribing Information]. Piscataway, NJ: Camber Pharmaceuticals, Inc.; 2025. [Accessed 09 Mar. 2025] (online) Available from:
Marketer details
Name: Steris Healthcare Pvt Ltd
Address: A.O. : 328-A, Tanaji Chowk, New Mill Road, Kurla (West), Mumbai 400070.
Country of origin: India
The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.
The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.
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10.0 tablets in 1 strip
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