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Valsac 100 Tablet

Sacubitril (49mg)+ Valsartan (51mg)

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Valsac 100 Tablet is a combination of two medicines used to treat heart failure. It works by improving heart function, lowering blood pressure, and reducing the risk of hospitalization and death in patients with long-lasting (chronic) heart failure. It is usually taken along with other heart failure medicines.

Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 22 Feb 2026 | 06:32 PM (IST)

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General Information

Contains

Sacubitril (49mg)+ Valsartan (51mg)

Marketer

Natco Pharma Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Valsac 100 Tablet may be taken with or without food. Take it at the same time each day for maximum benefits. Your doctor will decide the dose and how often you take it, and it may change depending on how well you respond to the medicine. Keep taking the tablets regularly, as prescribed, and try not to miss doses to get the most benefit. Do not stop taking them, even if you are feeling well. The medicine prevents future complications.

Common side effects of this medicine include low blood pressure (hypotension), impaired renal function, high potassium levels in the blood (hyperkalemia), cough, and dizziness. To reduce the risk of dizziness that may be caused by low blood pressure, try getting up slowly from a sitting or lying position. Tell your doctor if these or other side effects are severe or do not go away.

Before taking this medicine, tell your doctor if you are taking any other medication for blood pressure or heart conditions, or if you have kidney or liver disease. Also, let your doctor know all other medications you are using as they may affect, or be affected by, this medicine. This medicine should not be taken during pregnancy and is not recommended while breastfeeding. While on treatment with this medicine, your doctor may advise regular monitoring of blood pressure, kidney function, and potassium levels.

Uses of Valsac Tablet

Treatment of Heart Failure

Benefits of Valsac Tablet

Treatment of Heart Failure
Heart failure means your heart is weak and cannot pump enough blood to your lungs and the rest of your body. The most common symptoms are breathlessness, tiredness, and swelling in your legs, ankles, abdomen, and other body parts. Valsac 100 Tablet helps lower the blood pressure. This makes it easier for your heart to pump blood around your body and is, therefore, an effective treatment for heart failure. It also helps relieve your symptoms like breathlessness, tiredness, and swelling in your legs, making you feel better and more energetic. To help this medicine be effective, you should make appropriate lifestyle changes (such as eating healthily and staying active).

Side effects of Valsac Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Valsac

Hypotension (low blood pressure)
Increased potassium level in blood
Cough
Dizziness
Renal impairment

How to use Valsac Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Valsac 100 Tablet may be taken with or without food.

How Valsac Tablet works

Valsac 100 Tablet is a combination of two medicines: sacubitril and valsartan, which belong to a class of angiotensin receptor neprilysin inhibitors (ARNI). This combination treats heart failure by relaxing the blood vessels and making it easier for your heart to pump blood throughout your body. In addition, it also helps your body retain less water.

All substitutes for Valsac 100 Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

While taking Valsac 100 Tablet, you should continue to be active (light walking, stretching) and eat a healthy, low-sodium diet.
To reduce the chances of feeling dizzy, rise slowly if sitting or lying down.
Valsac 100 Tablet may raise the level of potassium in your blood. Avoid taking potassium supplements and eating potassium-rich foods such as bananas and broccoli.
Inform your doctor if you have a history of liver or kidney diseases.
Do not take Valsac 100 Tablet if you are pregnant or breastfeeding.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Valsac 100 Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Valsac 100 Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CONSULT YOUR DOCTOR

Valsac 100 Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

CONSULT YOUR DOCTOR

It is not known whether Valsac 100 Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney

CAUTION

Valsac 100 Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Regular blood pressure monitoring is recommended. No dose adjustment is needed in patients with mild to moderate kidney disease.

Liver

CAUTION

Valsac 100 Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
However, no dose adjustment is recommended in patients with mild liver disease. Valsac 100 Tablet is contraindicated in patients with severe liver disease.

Frequently asked questions

Who should avoid taking Valsac 100 Tablet?

Patients who are allergic to any of its components should avoid Valsac 100 Tablet. Those who are allergic to the use of ACE inhibitors or ARBs should also avoid using this medicine. It should not be used along with other antihypertensive medicines. Do not take it for at least 36 hours before or after you take an ACE inhibitor medicine. If you are not sure, consult your doctor.

What should I tell my doctor before taking Valsac 100 Tablet?

Tell your doctor about all of your medical conditions, including liver or kidney disease and a history of facial swelling (angioedema). Inform him if you are pregnant or are breastfeeding. Also, inform your doctor about all medicines you are taking, especially potassium supplements or medicine salt, painkillers, blood pressure, or heart failure medicines (such as ACE inhibitors, ARBs, or Aliskiren).

Can I use Valsac 100 Tablet in pregnancy?

No, Valsac 100 Tablet should be avoided in pregnancy. Its use can cause injury or even endanger the life of the baby. If you become pregnant while using Valsac 100 Tablet, stop using it and contact your doctor immediately.

How would I know if I have high potassium levels?

Your doctor will check your blood potassium levels periodically to detect high potassium levels (hyperkalemia). Make sure that you do not miss any scheduled appointments with the doctor.

Fact Box

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Therapeutic Class

CARDIAC

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Natco Pharma Ltd
Address: Natco House, Road No.2, Banjara Hills, Hyderabad-500 034, India

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Valsac 100 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945

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Valsac 100 Tablet

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Valsac Tablet

Benefits of Valsac Tablet

Side effects of Valsac Tablet

How to use Valsac Tablet

How Valsac Tablet works

All substitutes for Valsac 100 Tablet

CIDMUS 100mg Tablet

Azmarda 100mg Tablet

Vymada 100mg Tablet

Sacurise 100 Tablet

Arnicor 100 Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

Who should avoid taking Valsac 100 Tablet?

What should I tell my doctor before taking Valsac 100 Tablet?

Can I use Valsac 100 Tablet in pregnancy?

How would I know if I have high potassium levels?

Fact Box

Habit Forming

Therapeutic Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

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