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Sacubitril + Valsartan

Written By Dr. MayankReviewed By Dr. Rajeev Sharma
Last updated 13 Jun 2023 | 11:26 AM (UTC)

Sacubitril + Valsartan Uses

Sacubitril+Valsartan is used in the treatment of Heart Failure. It reduces the risk of hospitalization and death due to long lasting (chronic) heart failure.

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How Sacubitril + Valsartan works

Sacubitril + Valsartan is a combination of two medicines: Sacubitril and Valsartan which belong to a class of angiotensin receptor neprilysin inhibitor (ARNI). This combination treats heart failure by relaxing the blood vessels and making it easier for your heart to pump blood throughout your body. In addition, it also helps your body retain less water.

Common side effects of Sacubitril + Valsartan

Hypotension (low blood pressure), Dizziness, Cough, Increased potassium level in blood, Acute renal failure, Decreased hematocrit level, Increased creatinine level in blood
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Expert advice for Sacubitril + Valsartan

  • You have been prescribed Sacubitril + Valsartan for the treatment of of long-lasting (chronic) heart failure.
  • You should continue to stay active (light walking, stretching) and eat a healthy, low sodium diet along with taking this medication.
  • To reduce the chances of feeling dizzy, rise slowly if you have been sitting or lying down.
  • It may cause the level of potassium in your blood to go up. Avoid taking potassium supplements and potassium-rich foods such as banana and broccoli.
  • Inform your doctor if you have a history of liver or kidney diseases.
  • Do not take Sacubitril + Valsartan if you are pregnant or breastfeeding.

Frequently asked questions for Sacubitril + Valsartan

Patients who are allergic to any of its components should avoid Sacubitril+Valsartan. Also, those who are allergic to the use of ACE inhibitors or ARBs should avoid using this medicine. It should not be used along with other antihypertensive medicines like ACE inhibitors or ARBs. Do not take it for at least 36 hours before or after you take an ACE inhibitor medicine. If you are not sure, consult your doctor.
Tell your doctor about all of your medical conditions, including liver or kidney disease, history of facial swelling (angioedema). Inform him if you are pregnant or are breastfeeding. Also, let your doctor know about all medicines you are taking, especially potassium supplements or its medicine salt, painkillers, blood pressure or heart failure medicines (such as ACE inhibitor, ARBs or Aliskiren).
No, Sacubitril+Valsartan should be avoided in pregnancy. Its use can cause injury or even endanger the life of the baby. If you become pregnant while using Sacubitril+Valsartan, stop using it and contact your doctor immediately.
Your doctor will check your blood potassium levels periodically to detect high potassium levels (hyperkalemia). Make sure that you do not miss any scheduled appointments with the doctor.