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Sacubitril + Valsartan

Information about Sacubitril + Valsartan

Sacubitril + Valsartan Uses

Sacubitril+Valsartan is used in the treatment of Heart failure. It reduces the risk of hospitalization and death due to long lasting (chronic) heart failure.

How Sacubitril + Valsartan works

Sacubitril + Valsartan is a combination of two medicines: Sacubitril and Valsartan which belong to a class of angiotensin receptor neprilysin inhibitor (ARNI). This combination treats heart failure by relaxing the blood vessels and making it easier for your heart to pump blood throughout your body. In addition, it also helps your body retain less water.

Common side effects of Sacubitril + Valsartan

Orthostatic hypotension (sudden lowering of blood pressure on standing), Renal impairment, Decreased blood pressure, Cough, Dizziness, Altered levels of potassium in blood, Diarrhea, Decreased red blood cell count, Headache, Fainting, Weakness, Nausea, Stomach pain, Hypoglycemia (low blood glucose level), Vertigo
Written By
Reviewed By
MD (Pharmacology), MBBS
Last updated:
23 Mar 2021 | 01:19 PM (UTC)

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Available Medicine for Sacubitril + Valsartan

VymadaNovartis India Ltd
681 to ₹23625 variant(s)
CidmusLupin Ltd
677 to ₹11743 variant(s)
AzmardaCipla Ltd
669 to ₹11693 variant(s)
ValsacNatco Pharma Ltd
1260 to ₹15402 variant(s)
SacutanMSN Laboratories
1050 to ₹15002 variant(s)
ZayoEris Lifesciences Ltd
350 to ₹15005 variant(s)

Expert advice for Sacubitril + Valsartan

  • You have been prescribed Sacubitril + Valsartan for the treatment of of long-lasting (chronic) heart failure.
  • You should continue to stay active (light walking, stretching) and eat a healthy, low sodium diet along with taking this medication.
  • To reduce the chances of feeling dizzy, rise slowly if you have been sitting or lying down.
  • It may cause the level of potassium in your blood to go up. Avoid taking potassium supplements and potassium-rich foods such as banana and broccoli.
  • Inform your doctor if you have a history of liver or kidney diseases.
  • Do not take Sacubitril + Valsartan if you are pregnant or breastfeeding.

Frequently asked questions for Sacubitril + Valsartan

Sacubitril + Valsartan

Q. Who should avoid taking Sacubitril+Valsartan?

Patients who are allergic to any of its components should avoid Sacubitril+Valsartan. Also, those who are allergic to the use of ACE inhibitors or ARBs should avoid using this medicine. It should not be used along with other antihypertensive medicines like ACE inhibitors or ARBs. Do not take it for at least 36 hours before or after you take an ACE inhibitor medicine. If you are not sure, consult your doctor.

Q. What should I tell my doctor before taking Sacubitril+Valsartan?

Tell your doctor about all of your medical conditions, including liver or kidney disease, history of facial swelling (angioedema). Inform him if you are pregnant or are breastfeeding. Also, let your doctor know about all medicines you are taking, especially potassium supplements or its medicine salt, painkillers, blood pressure or heart failure medicines (such as ACE inhibitor, ARBs or Aliskiren).

Q. Can I use Sacubitril+Valsartan in pregnancy?

No, Sacubitril+Valsartan should be avoided in pregnancy. Its use can cause injury or even endanger the life of the baby. If you become pregnant while using Sacubitril+Valsartan, stop using it and contact your doctor immediately.

Q. How would I know if I have high potassium levels?

Your doctor will check your blood potassium levels periodically to detect high potassium levels (hyperkalemia). Make sure that you do not miss any scheduled appointments with the doctor.


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