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Valentas D 100 Tablet is used to manage heart failure with reduced ejection fraction. It helps improve heart function, reduce fluid buildup, and support better control of symptoms like breathlessness and fatigue.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 31 Mar 2026 | 12:04 PM (IST)
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Valentas D 100 Tablet image
Valentas D 100 Tablet image
Valentas D 100 Tablet image
Valentas D 100 Tablet image
Valentas D 100 Tablet image

Product introduction

Take Valentas D 100 Tablet regularly at the same time each day as prescribed by your doctor. Do not stop or change the dose without medical advice, even if you feel better. Monitor your weight and symptoms such as swelling or breathlessness regularly and report any sudden changes to your doctor. Follow a low-salt diet, limit fluid intake if advised, and keep regular follow-up visits to monitor kidney function, blood pressure, and overall heart status.


Some individuals may experience side effects such as hypoglycemia, urinary tract infections, increased urination (polyuria), and discomfort or pain during urination (dysuria). Other possible effects include dizziness, rash, back pain, and genital itching, such as vulvovaginal pruritus. If any symptoms persist or worsen, consult your doctor.


Do not use this medicine if you are allergic to any of its components or if you have a history of angioedema related to similar medicines. Inform your doctor if you have diabetes, are taking diuretics, or are at risk of electrolyte imbalance. Seek medical attention if you experience severe dizziness, fainting, reduced urine output, or swelling of the face, lips, or throat.

Uses of Valentas D Tablet

Benefits of Valentas D Tablet

Heart Failure
Valentas D 100 Tablet is used to manage heart failure with reduced ejection fraction, a condition where the heart does not pump blood effectively. It helps reduce symptoms such as breathlessness, fatigue, and fluid buildup in the body. This leads to improved heart function and better circulation. As a result, patients may experience better symptom control and improved daily activity.

Side effects of Valentas D Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Valentas D
  • Hypoglycemia (low blood glucose level)
  • Hypotension (low blood pressure)
  • Dyslipidemia
  • Increased potassium level in blood
  • Increased creatinine level in blood
  • Dizziness
  • Cough
  • Rash
  • Urinary tract infection
  • Back pain
  • Discomfort when urinating
  • Vulvovaginal discomfort

How to use Valentas D Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Valentas D 100 Tablet may be taken with or without food.

How Valentas D Tablet works

Valentas D 100 Tablet works by improving heart function and reducing strain on the heart through multiple mechanisms. Dapagliflozin helps remove excess fluid from the body by increasing urine output, which reduces the workload on the heart. Sacubitril helps increase beneficial substances that relax blood vessels and reduce fluid retention. Valsartan blocks certain receptors that cause blood vessels to narrow, helping them relax and lowering the strain on the heart. Together, these actions help improve blood flow, reduce fluid buildup, and support better heart function.

Quick tips

  • Monitor your body weight daily at the same time. A sudden increase (for example, more than 1–2 kg over a few days) may indicate fluid retention and should be reported to your doctor promptly.
  • Check your blood pressure regularly, especially during the initial weeks of treatment or after dose adjustments. If you experience persistent dizziness, lightheadedness, or fainting, seek medical advice.
  • Maintain a low-salt diet, as excess sodium can worsen fluid retention and reduce the effectiveness of heart failure treatment. Avoid processed and packaged foods that are high in hidden salt.
  • Inform your doctor immediately if you develop symptoms of dehydration (persistent vomiting, diarrhea, excessive sweating), as a temporary dose adjustment or interruption may be required.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Valentas D 100 Tablet. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Valentas D 100 Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Valentas D 100 Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Valentas D 100 Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney

Kidney

CAUTION
Valentas D 100 Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Liver

Liver

SAFE IF PRESCRIBED
Valentas D 100 Tablet is safe to use in patients with liver disease. No dose adjustment is recommended.
Valentas D 100 Tablet should not be used in severe liver conditions.

Frequently asked questions

Some patients may begin to notice relief in symptoms such as reduced swelling or improved breathing within a few weeks of regular use. However, heart failure treatment is intended for long-term disease control, and the full benefits develop gradually over time. It is important to continue the medication as prescribed, even if symptoms improve early.
Yes. Heart failure is a chronic condition that requires ongoing treatment. Symptom improvement usually indicates that the medicine is working, not that the condition has resolved. Stopping or changing the dose without medical advice may lead to worsening symptoms or disease progression.
Valentas D 100 Tablet works best when combined with heart failure lifestyle management. Patients are usually advised to limit salt intake, monitor daily fluid intake if recommended, maintain a healthy weight, and stay physically active as tolerated. Regular follow-up visits are important to assess treatment response.
Patients should regularly monitor their body weight, blood pressure, and symptoms. Sudden weight gain, increasing leg swelling, worsening breathlessness, unusual fatigue, dizziness, or reduced urine output should be reported to a doctor, as these may indicate fluid retention or changes in heart function.
Patients with low blood pressure, dehydration, or diabetes, or those taking diuretics or multiple heart medications, should inform their doctor before starting treatment. Dose adjustments or closer monitoring may be required in such cases.

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Lupin Ltd
Address: 159,CST road ,Kalina ,Santacruz ,Mumbai ,-400 098,India

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Valentas D 100 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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