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09 Jul 2020 | 11:47 AM (IST)
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Ursocol 300 Tablet

Prescription Required
Salt Synonyms
Storage
Store at room temperature (10-30°C)
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Introduction

Ursocol 300 Tablet is a medicine used to dissolve certain types of gallstones, to prevent them from forming and to treat a type of liver disease called primary biliary cirrhosis. It is a bile acid which helps break down cholesterol which has formed into stones in your gallbladder.

Ursocol 300 Tablet should be taken after a meal with a glass of milk or water. The dose will depend on what you are being treated for and your body weight. It would be best to swallow it whole. This medicine needs to be taken regularly to get the most benefit and you may have to take it for several months or longer, so try to get into a routine. Keep using it as prescribed even if your symptoms disappear. Even if the gallstones completely dissolve, the treatment should still be continued for several weeks or months.

The most common side effects are abdominal pain, diarrhea, hair loss, itching, nausea, and rash. Not everyone gets side effects. If you are worried about them, or they do not go away, let your doctor know. If you have problems with diarrhea your doctor may reduce the dose or stop the treatment.

Before taking this medicine, you should tell your doctor if you have an inflammation of the gallbladder or bile ducts, you get frequent cramp-like pain in your upper abdomen, you have been coughing up blood or you have gained weight rapidly. Using this medicine can reduce or increase the effect of some other medicines so tell your doctor all other medicines you are taking. Women who use this medicine for dissolving gallstones should stop using the birth control pill because the hormones present in it can increase the production of gallstones. During the treatment, you may need ultrasound scans, or frequent blood tests to check your liver function.

Uses of Ursocol Tablet

Benefits of Ursocol Tablet

In Primary biliary cirrhosis

Primary biliary cholangitis is a type of liver disease that gradually gets worse over time. It does not always have symptoms but, over time, it can lead to liver failure. Ursocol 300 Tablet is used to treat this condition and may be used by itself or with other medicines. It can help prevent or delay liver damage in most people, especially if you start taking it in the early stages. Once you start this treatment, it is likely that you will be taking it for the rest of your life. To make the medicine more effective and for general health benefits, you can help yourself by stopping smoking, keeping a healthy weight, and not drinking too much alcohol.

In Gallbladder stones

Ursocol 300 Tablet is a medicine that helps decreases the amount of cholesterol produced by your liver. It helps to break down cholesterol that has formed into “stones” in the gallbladder. It may take several months to completely dissolve the stone, so you need to take the medicine regularly and as long as the doctor has prescribed it for it to be effective. There might be other medicines and certain lifestyle changes that can reduce your cholesterol level and make gallstones less likely, consult with your doctor.

Side effects of Ursocol Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Ursocol

  • Abdominal pain
  • Diarrhea
  • Hair loss
  • Itching
  • Nausea
  • Rash

How to use Ursocol Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Ursocol 300 Tablet is to be taken with food.

How Ursocol Tablet works

Ursocol 300 Tablet is a hepatoprotective medication. It works by reducing the amount of cholesterol in the blood and helps dissolve gallbladder stones that are composed mainly of cholesterol. It also improves liver enzymes, protects liver cells from injury caused due to toxic bile acids, and improves liver function.

Safety Advice

Alcohol
UNSAFE
Ursocol 300 Tablet may cause excessive drowsiness with alcohol.
Pregnancy
SAFE IF PRESCRIBED
Ursocol 300 Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breastfeeding
SAFE IF PRESCRIBED
Ursocol 300 Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
SAFE
Ursocol 300 Tablet does not usually affect your ability to drive.
Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Ursocol 300 Tablet in patients with kidney disease. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Ursocol 300 Tablet in patients with liver disease. Please consult your doctor.

What if you forget to take Ursocol Tablet?

If you miss a dose of Ursocol 300 Tablet, skip it and continue with your normal schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Ursocol 300 Tablet
₹26.3/Tablet
Sorbidiol 300 Tablet
Franco-Indian Pharmaceuticals Pvt Ltd
₹24.13/Tablet
save 8%
Urdohep 300 Tablet
Macleods Pharmaceuticals Pvt Ltd
₹29.64/Tablet
13% costlier
₹31.49/Tablet
20% costlier
₹34.49/Tablet
31% costlier
Bilefix 300 Tablet
Dr Reddy's Laboratories Ltd
₹35.16/Tablet
34% costlier

Quick Tips

  • Ursocol 300 Tablet should be taken after a meal with a glass of milk or water.
  • Eat a healthy diet, exercise regularly and avoid alcohol intake.
  • Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if diarrhea persists or if you find blood in your stools.
  • Your doctor may monitor your liver function and bilirubin levels every month for next 3 months after the start of therapy, and every 6 months thereafter.
  • Do not stop taking the medication without talking to your doctor.

Fact Box

Chemical Class
Bile Acids and Salts
Habit Forming
No
Therapeutic Class
GASTRO INTESTINAL

Interaction with Drugs

Taking Ursocol with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Imudrops, Neoral, Aurosporine
SERIOUS

Patient Concerns

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Having gall stones (1.8cm) since 6 years. Taking Ursocol twice a day will it help to dissolve the gall stones
Dr. Pushkar Mani
Physician
that can be confirmed by USG , kindly do full abdomen USG and CXR(Pa view)
Sir ! For gallbladder stones medicine pl!
Dr. Deepak Kumar Soni
Ayurveda
https://goo.gl/forms/TPKaRvl1NqrBq4Zj2
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Do you have any questions related to Ursocol 300 Tablet ?

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FAQs

Q. When should I take Ursocol 300 Tablet?

The suitable timing of taking this medicine might differ depending upon your condition. Your doctor might instruct you to take 2 to 3 doses per day and suggest to take the last dose at bedtime. Ursocol 300 Tablet should be taken with water milk and can be taken with food or after food. When prescribed for dissolving gallstones, it is usually suggested to be taken once daily at night. Ideally, it should be taken at a gap of 6 hours, for example at 8 am, 2 pm and 8 pm.

Q. Is Ursocol 300 Tablet safe?

Ursocol 300 Tablet is usually considered to be a safe and effective medicine. However, this medicine may have some common side effects, such as diarrhea. If diarrhea occurs, your doctor may reduce the dose and if it persists, your treatment may be discontinued. Additionally, using this medicine as a long term therapy may also affect your liver enzyme levels. To keep a check on this, your doctor will keep monitoring your liver enzyme levels regularly. Despite these minor side effects, this medicine is supposed to be a good alternative to surgery in some patients with gallstones.

Q. How does Ursocol 300 Tablet help the liver?

Ursocol 300 Tablet acts on the liver and gets concentrated in the bile secreted from the liver. This, as a result, suppresses the synthesis and secretion of cholesterol by the liver, thereby decreasing the cholesterol levels in bile. This medicine also acts by stopping the intestines from absorbing the bile salts and cholesterol. So, the reduced cholesterol saturation in the bile from the liver leads to gradual dissolving of cholesterol from gallstones, leading to a decrease in size and their eventual dissolution. It also reduces elevated liver enzyme levels by increasing the bile flow through the liver, hence protecting the liver cells.

Q. Does Ursocol 300 Tablet cause weight gain?

Yes, there is a chance of weight gain with Ursocol 300 Tablet, but it is not common. The use of Ursocol 300 Tablet can cause weight gain when prescribed in patients with liver disease associated with chronic stasis of bile in small bile ducts of the liver. In such condition bile cannot flow from the liver to the small intestine. Again, the chance of weight gain varies from person to person depending upon the disease, so consult your doctor if you experience weight gain.

Q. What should I avoid while taking Ursocol 300 Tablet?

While taking Ursocol 300 Tablet, avoid taking an antacid preparation without consulting your doctor, as they decrease the effectiveness of Ursocol 300 Tablet. You should also avoid medicines like cholestyramine or colestipol as they affect the effectiveness of Ursocol 300 Tablet. So, ask your doctor about the time gap that should be maintained between Ursocol 300 Tablet and these medicines. Also, avoid taking oral contraceptives, estrogenic hormones and blood cholesterol-lowering agents such as clofibrate as they may increase the chances of developing gallstones and act opposite to the Ursocol 300 Tablet.

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1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Ursodiol. Birmingham, Alabama: Axcan Pharma US, Inc.; 1997 [revised Nov. 2009]. [Accessed 25 Jan. 2019] (online) Available from:External Link
  2. Ursodiol. Bridgewater, New Jersey: Aptalis Pharma US, Inc.; 1997 [revised Jun. 2013]. [Accessed 28 Mar. 2019] (online) Available from:External Link
  3. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Ursodiol. [Updated 2020 Jan 20]. [Accessed 20 Feb. 2020] (online) Available from:External Link

Manufacturer/Marketer Address

90, Delhi - Jaipur Road, Sector 32, Gurugram, Haryana 122001
Country of Origin: India
Best Price
₹223.55
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