Unogest 400mg Vaginal Pessaries is used to restore menstrual cycles in women whose periods have stopped. It is a natural female hormone important for regulating ovulation (release of an egg from a woman's ovary) and menstruation. It is also used in the treatment of infertility to help you get pregnant.
You should use Unogest 400mg Vaginal Pessaries as your doctor has advised. Do not use more or less than you have been advised and do not use it for longer than recommended. You may be asked to continue taking this medicine for a period after it is confirmed that you are pregnant.
The most common side effects include headache, feeling very tired, stomach cramps, pain or swelling in your abdomen and feeling sick. You may also feel bloated, less interested in sex and get pain or discharge in your vagina. Your doctor or nurse may be able to help you reduce or prevent side effects if they bother you or do not go away. Very occasionally people get a severe allergic reaction which needs urgent medical attention. Using this medicine may increase your risk of blood clots or breast cancer.
Unogest 400mg Vaginal Pessaries may not suit everybody, and you should tell your doctor if you have, or have had, breast cancer, unusual bleeding in the vagina or liver disease. You may be monitored more carefully if you have liver, kidney or heart problems or have diabetes or asthma. Let your doctor know your medical history to be safe. Check with your doctor about all other medicines which may affect, or be affected by, this medicine. You will probably have several tests both before and during treatment to check your womb. This medicine can alter your thinking or reactions and you may feel very tired so be careful if you drive or need to be alert. In general, alcohol is not recommended while taking this medicine.
Unogest 400mg Vaginal Pessaries contains progesterone, a female hormone that is important in the regulation of ovulation and menstruation. It is used to cause menstrual periods in women who have not reached menopause but are not having periods due to a lack of natural progesterone in the body. Progesterone helps to prepare the uterus for pregnancy by causing the uterus lining (endometrium) to thicken. This increases the chance of a successful pregnancy. You should use the medicine as prescribed for it to be effective. You may be asked to continue with this treatment for a period after becoming pregnant.
In Hormone replacement therapy
Hormone Placement Therapy (HRT) is a treatment to relieve symptoms of menopause such as hot flushes, night sweats, mood swings, vaginal dryness, and reduced sex drive. Since menopause can last for several years, this treatment can make a big improvement to your daily life and mood. Progesterone is one of two important hormones (the other is estrogen) used in this treatment. Vaginal tablets and gels are an easy way to deliver hormones but may not treat all the symptoms. You should use this medicine as it is prescribed, and for as long as it is prescribed by your doctor.
Side effects of Unogest Pessaries
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Unogest
Fatigue
Headache
Joint pain
Abnormal menstrual bleeding
Musculoskeletal (bone, muscle or joint) pain
Vertigo
How to use Unogest Pessaries
Take this medicine in the dose and duration as advised by your doctor. Wash and dry your vaginal area. Lie on your back and gently insert the pessary into the vagina as high as possible with or without the use of an applicator as mentioned in the label.
How Unogest Pessaries works
Unogest 400mg Vaginal Pessaries contains a progesterone (a female sex hormone). It helps to establish and maintain pregnancy. It also prevents the increase in thickness of the endometrium (lining of the uterus) caused by estrogen.
Safety advice
Alcohol
No interaction found/established
Pregnancy
CONSULT YOUR DOCTOR
Unogest 400mg Vaginal Pessaries may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Unogest 400mg Vaginal Pessaries is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
No interaction found/established
Kidney
No interaction found/established
Liver
No interaction found/established
What if you forget to take Unogest Pessaries?
If you miss a dose of Unogest 400mg Vaginal Pessaries, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Unogest 400mg Vaginal Pessaries helps increase your chances of getting pregnant. It prepares the lining of your uterus to receive and nourish a fertilized egg.
If you become pregnant, it can be used for another 10 to 12 weeks until your progesterone levels are high enough.
It also helps regulate menstrual cycle in women who do not have a regular period due to a decrease in the hormone progesterone.
It exposes your body to less hormone invasion compared to pills or injections thereby preventing various gastric side effects.
Do not use tampons or other vaginal products for at least 6 hours before and after using Unogest 400mg Vaginal Pessaries.
You may get a brownish or white discharge during this time. It is not unusual, but talk to your doctor if it bothers you.
Fact Box
Chemical Class
Progesterone Derivative
Habit Forming
No
Therapeutic Class
GYNAECOLOGICAL
Action Class
Natural Progesterone
Interaction with drugs
Taking Unogest with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Progesterone is not recommended in individuals with known, suspected, or history of breast cancer. Progesterone may oppose anticancer effects of Tamoxifen.
Avoid concurrent use. P... More
Concurrent use may increase the risk of formation of blood clots.
If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observatio... More
I am a male to female transsexual and I need Bilateral Orchiectomy at a fair cost I am already on hormone replacement therapy for 2 years anti androgen/spirnolactone (Aldactone) and estrodiol valerate progynova, I need to have bilateral orchiectomy at the cheapest option
I have sexual hormone problem and infertility problem. 30 millions sperm count,motility 50 only.please send me prescription.
Dr. Pranay Gandhi
Sexology
sperm count is normal so is motility. for increasing ur testosterone levels 1.stop smoking and alcohol 2.join a gym and reduce weight. Do weight lifting exercises. 3.tablet sildenafil or viagra 1 tablet 1 hour before sexual activity. 4.Get tested so that u don?t have any of the following causes: 1.heart diseases 2. diabetes 3.neurological problems 4.hormonal problems 5.drug side effects
Male hormone testosterone is found less in the recent blood test around 270,shall I take hormone therapy like tablet cents regularly what will be the dose and limitations in use
What are the side effects of prolonged usage of thyronorm medicine as I am having hypothyroidism since the last 20 years and I am taking the medicine since then . Thanks
Dr. Sfurti Mann
Internal Medicine
It is thyroxin hormone given as replacement of the hormone thyroxin which your body is not producing adequately. If it is being taken in the correct dose maintains your TSH in normal range then it has no side effects.
30 years infertility problems like erectile disfunction and 0 sperm bcoz of total hormone suppression. Please recommend an effective solution. Thank you
Dr. Asmita Kaundal
Obstetrics and Gynaecology
plzz see an andrologist in person v dont ve any doctor on 1mg for maleninfertility
I am suffering from irregular periods ,after 1 or 2 months ,menstruation cycle reduces to 13 days. Normally it was of 24 days. Uterus has developed small fibroids also which are multiple. Periods remain heavy also.
Dr. Sonu Balhara Ahlawat
Obstetrics and Gynaecology
Can start with hormone therapy after consulting a gynaecologist
What were the side-effects while using Unogest 400mg Vaginal Pessaries?
No Side Effec*
100%
*No Side Effect
FAQs
What is Unogest 400mg Vaginal Pessaries and what is it used for?
Unogest 400mg Vaginal Pessaries is a synthetic form of micronized progesterone, which is a natural female sex hormone. It is used to treat menstrual and pregnancy-related issues that are caused due to hormonal imbalance. It is also prescribed along with estrogen as a part of hormonal replacement therapy to prevent endometrial hyperplasia (thickening of the lining of the uterus).
How and in what dose should I take Unogest 400mg Vaginal Pessaries?
Unogest 400mg Vaginal Pessaries should be taken strictly as advised by your doctor. The dose and duration will depend on your exact medical condition. It is recommended to use it at the same time each day to ensure consistent levels of medicine in your body.
Is Unogest 400mg Vaginal Pessaries safe?
Unogest 400mg Vaginal Pessaries is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.
What if I miss to take Unogest 400mg Vaginal Pessaries?
If you miss the dose, you should take it as soon as possible. If it is almost time for your next dose, skip the missed dose and continue with your usual dosing schedule. Do not take a double dose to make up for the missed one.
What are the common side effects which I can experience while taking Unogest 400mg Vaginal Pessaries?
The common side effects include vaginal discharge, headache, feeling tired, stomach cramps and breast tenderness. If any of the side effects bother you, please consult with your doctor.
Is Unogest 400mg Vaginal Pessaries effective?
Unogest 400mg Vaginal Pessaries is effective if used in the dose and duration advised by your doctor. Do not stop taking it even if you see improvement in your condition. If you stop using Unogest 400mg Vaginal Pessaries too early, the symptoms may return or worsen.
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
Chrousos GP. The Gonadal Hormones & Inhibitors. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 706-707.
Levin ER, Hammes SR. Estrogens and Progestins. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1180-85.
Progesteroene. Feltham, Middlesex: Merck; 2013 [revised Mar. 2015]. [Accessed 03 Apr. 2019] (online) Available from: