Product introduction
Tybriva Capsule is used in the treatment of mantle-cell lymphoma and blood cancer (chronic lymphocytic leukemia). It is also used in chronic lymphocytic leukaemia who have received at least one prior therapy.
Tybriva Capsule is taken in a dose as advised by the doctor. The duration of treatment varies on the basis of your response to treatment. Your doctor may get regular blood tests to check number of blood cells during treatment with this medicine. It is known to reduce the number of blood cells in your blood thereby, increasing the susceptibility to infections. It may cause headache, diarrhea, and nausea as its side effects.
Uses of Tybriva Capsule
Benefits of Tybriva Capsule
In Blood cancer (Chronic lymphocytic leukemia)
Chronic lymphocytic leukemia (CLL) is a slow-growing blood cancer in which the bone marrow makes abnormal white blood cells that crowd out healthy cells and weaken the immune system. Tybriva Capsule helps block signals that cancer cells need to grow and multiply, slowing disease progression and supporting healthier blood cell balance. This helps manage symptoms, maintain immune function, and improve quality of life.
In Mantle-cell lymphoma
Mantle-cell lymphoma is a type of non-Hodgkin lymphoma that affects lymph nodes and other parts of the lymphatic system. Tybriva Capsule helps stop cancer cells from growing and spreading, allowing for better disease control. This can reduce symptoms, slow disease advancement, and extend periods without disease progression.
Side effects of Tybriva Capsule
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Tybriva
- Fever
- Headache
- Fatigue
- Musculoskeletal (bone, muscle or joint) pain
- Rash
- Anemia (low number of red blood cells)
- Bruising
- Muscle spasm
- Hemorrhage
- Pneumonia
- Cough
- Diarrhea
- Stomatitis (Inflammation of the mouth)
- Nausea
- Low blood platelets
- Decreased white blood cell count (neutrophils)
- Dry eye
- High blood pressure
- Weight loss
- Urinary tract infection
- Peripheral edema
- Subdural hematoma
- Second primary malignancies
How to use Tybriva Capsule
Take this medicine in the dose and duration as advised by your doctor. Tybriva Capsule may be taken with or without food, but it is better to take it at a fixed time.
How Tybriva Capsule works
Tybriva Capsule is a Bruton's tyrosine kinase inhibitor. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Tybriva Capsule. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Tybriva Capsule is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
CAUTION
Tybriva Capsule should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
Driving
UNSAFE
Tybriva Capsule may cause side effects which could affect your ability to drive.
Kidney
CAUTION
Tybriva Capsule should be used with caution in patients with kidney disease. Dose adjustment of Tybriva Capsule may be needed. Please consult your doctor.
Liver
CAUTION
Tybriva Capsule should be used with caution in patients with liver disease. Dose adjustment of Tybriva Capsule may be needed. Please consult your doctor.
What if you forget to take Tybriva Capsule?
If you miss a dose of Tybriva Capsule, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
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Quick tips
- Take it at the same time every day, either with or without food.
- It is advisable to stay hydrated and drink plenty of fluids while taking this medication.
- Do not skip any dose and complete the course as suggested by your doctor.
- Use an effective method of birth control to avoid pregnancy while taking this medication.
- Your doctor may get regular blood tests done to monitor your liver function and blood cell count in your blood.
- Take it at the same time every day, either with or without food.
- It is advisable to stay hydrated and drink plenty of fluids while taking this medication.
- Do not skip any dose and complete the course as suggested by your doctor.
- Use an effective method of birth control to avoid pregnancy while taking this medication.
- Your doctor may get regular blood tests done to monitor your liver function and blood cell count in your blood.
Fact Box
Chemical Class
Diphenylethers Derivative
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Bruton's tyrosine kinase (BTK) inhibitors
Interaction with drugs
Taking Tybriva with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Talk to your doctor if you notice any unusual symptoms.
Concurrent use may increase the risk of bleeding.
Inform your doctor if you notice any signs of bleeding (bruising, bleeding gums, blood in stool/vomit/urine).
Concurrent use may increase the risk of bleeding.
Talk to your doctor if you notice any unusual symptoms. Ibrutinib may raise blood levels of Fluvastatin.
Talk to your doctor if you notice any unusual symptoms. Ibrutinib may raise blood levels of Methotrexate.
Talk to your doctor regarding effective contraception during the simultaneous use of these medicines.
No significant interaction is generally observed.
Patient concerns
FAQs
What is Tybriva Capsule used for?
Tybriva Capsule is used in the treatment of mantle-cell lymphoma and blood cancer (chronic lymphocytic leukemia). In patients having chronic lymphocytic leukemia, this medicine is given only if they have undergone at least one previous treatment.
Who should not take Tybriva Capsule?
There are no absolute contraindications listed, but Tybriva Capsule may not be suitable for everyone. Patients with severe liver disease or certain medical conditions may require dose adjustments or close monitoring. Your doctor will closely assess your condition before starting Tybriva Capsule treatment.
What warnings of Tybriva Capsule should I know about before starting Tybriva Capsule?
Tybriva Capsule can increase the risk of bleeding, infections, heart rhythm problems, high blood pressure, liver damage, and other serious side effects. Regular monitoring with blood tests and medical checkups is necessary during treatment.
Can Tybriva Capsule cause heart problems?
Yes, Tybriva Capsule has been linked to irregular heartbeats (arrhythmias), heart failure, and even sudden death in rare cases. Patients with a history of heart disease should inform their doctor before starting Tybriva Capsule therapy.
Does Tybriva Capsule increase the risk of infections?
Yes, Tybriva Capsule can lower your body’s ability to fight infections. Patients may develop fevers, pneumonia, or other serious infections. Any sign of infection should be reported to your doctor right away.
Can Tybriva Capsule cause bleeding or bruising?
Yes, bleeding problems such as bruising, nosebleeds, or more serious internal bleeding can happen with Tybriva Capsule. If you are taking blood thinners or have a bleeding disorder, you must inform your doctor before starting Tybriva Capsule.
What are the serious side effects of Tybriva Capsule?
Serious side effects of Tybriva Capsule include severe bleeding, life-threatening infections, liver damage, high blood pressure, heart rhythm problems, secondary cancers such as skin cancer, and tumor lysis syndrome (a complication when cancer cells break down too quickly). Seek immediate medical attention if you experience any of these symptoms.
Can Tybriva Capsule cause liver damage?
Yes, Tybriva Capsule has been linked to hepatotoxicity, which means it can cause liver injury. Doctors usually monitor liver function with blood tests during treatment.
Can Tybriva Capsule cause other cancers?
Yes, some patients on Tybriva Capsule have developed second cancers, including skin cancers and other types of carcinoma. Skin checks and regular monitoring are recommended during Tybriva Capsule treatment.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:
- Ibrutinib. Beerse Belgium: Janssen Pharmaceutica NV; [Accessed on 27 Mar. 2019] (online) Available from:
Marketer details
Name: Emcure Pharmaceuticals Ltd
Address: 255/2, Hinjawadi, Pune - 411057, India
Country of origin: India
Expires on or after: January, 2026
A licensed vendor partner from your nearest location will deliver Tybriva Capsule. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Expires on or after: January, 2026
A licensed vendor partner from your nearest location will deliver Tybriva Capsule. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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MRP₹9843.75 9% OFF
₹8952
Inclusive of all taxes
30.0 capsules in 1 bottle
New GST benefit included in this MRP, may differ from label
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